Crucial roles of mixed-lineage leukemia 3 and 4 as epigenetic switches of the hepatic circadian clock controlling bile acid homeostasis in mice

Nuclear receptors and metabolism: from feast to famine

(2014) Suk-Hyun Hong et al.   DIABETOLOGIA

Pleiotropic Roles of Bile Acids in Metabolism

(2013) Thomas Q. de Aguiar Vallim et al.   Cell Metabolism

Histone methyltransferase MLL3 contributes to genome-scale circadian transcription

(2013) Utham K. Valekunja et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone H3 lysine 4 methyltransferases and demethylases in self-renewal and differentiation of stem cells

(2013) Bingnan Gu et al.   Cell and Bioscience

RORγ directly regulates the circadian expression of clock genes and downstream targets in vivo

(2012) Yukimasa Takeda et al.   NUCLEIC ACIDS RESEARCH

Histone H3K4 trimethylation by MLL3 as part of ASCOM complex is critical for NR activation of bile acid transporter genes and is downregulated in cholestasis

(2011) M. Ananthanarayanan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Crosstalk between Components of Circadian and Metabolic Cycles in Mammals

(2011) Gad Asher et al.   Cell Metabolism

Requirement for MLL3 in p53 Regulation of Hepatic Expression of Small Heterodimer Partner and Bile Acid Homeostasis

(2011) Dae-Hwan Kim et al.   MOLECULAR ENDOCRINOLOGY

Tumor suppressor p53 regulates bile acid homeostasis via small heterodimer partner

(2011) D.-H. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ASCOM Controls Farnesoid X Receptor Transactivation through Its Associated Histone H3 Lysine 4 Methyltransferase Activity

(2009) Dae-Hwan Kim et al.   MOLECULAR ENDOCRINOLOGY

The Benzenesulfoamide T0901317 [N-(2,2,2-Trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide] Is a Novel Retinoic Acid Receptor-Related Orphan Receptor- /  Inverse Agonist

(2009) N. Kumar et al.   MOLECULAR PHARMACOLOGY

Regulation of Bile Acid Synthesis by the Nuclear Receptor Rev-erbα

(2008) Hélène Duez et al.   GASTROENTEROLOGY

Activating Signal Cointegrator-2 Is an Essential Adaptor to Recruit Histone H3 Lysine 4 Methyltransferases MLL3 and MLL4 to the Liver X Receptors

(2008) Seunghee Lee et al.   MOLECULAR ENDOCRINOLOGY

Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor

(2008) Francisco J. Quintana et al.   NATURE

Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis

(2008) J. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA