Aging- and vascular-related pathologies

Hypertension and Inflammation in Alzheimer's Disease: Close Partners in Disease Development and Progression!

(2018) Lucy Nelson et al.   JOURNAL OF ALZHEIMERS DISEASE

Mechanisms of foam cell formation in atherosclerosis

(2017) Dimitry A. Chistiakov et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

(2017) Paul M Ridker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Senescent intimal foam cells are deleterious at all stages of atherosclerosis

(2016) B. G. Childs et al.   SCIENCE

Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis

(2016) Y. Iturria-Medina et al.   Nature Communications

Angiogenesis-regulating microRNAs and Ischemic Stroke

(2015) Ke-Jie Yin et al.   Current Vascular Pharmacology

Compromised blood-brain barrier competence in remote brain areas in ischemic stroke rats at the chronic stage

(2014) Svitlana Garbuzova-Davis et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Age-Associated Increase in Cytokine Production During Systemic Inflammation—II: The Role of IL-1β in Age-Dependent IL-6 Upregulation in Adipose Tissue

(2014) Marlene E. Starr et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

The role of senescent cells in ageing

(2014) Jan M. van Deursen   NATURE

Blood Brain Barrier and Neuroinflammation Are Critical Targets of IGF-1-Mediated Neuroprotection in Stroke for Middle-Aged Female Rats

(2014) Shameena Bake et al.   PLoS One

Transcriptomics of Post-Stroke Angiogenesis in the Aged Brain

(2014) Ana Maria Buga et al.   Frontiers in Aging Neuroscience

Age-related changes in brain support cells: Implications for stroke severity

(2013) Farida Sohrabji et al.   NEUROCHEMISTRY INTERNATIONAL

The Systemic Cytokine Environment Is Permanently Altered in Multiple Myeloma

(2013) Mary M. Zheng et al.   PLoS One

Aging is associated with chronic innate immune activation and dysregulation of monocyte phenotype and function

(2012) Anna C. Hearps et al.   AGING CELL

Aging is associated with circulating cytokine dysregulation

(2012) Lorena Álvarez-Rodríguez et al.   CELLULAR IMMUNOLOGY

Age-related defects in TLR2 signaling diminish the cytokine response by alveolar macrophages during murine pneumococcal pneumonia

(2012) Angela R. Boyd et al.   EXPERIMENTAL GERONTOLOGY

Endothelial progenitor cells in atherosclerosis

(2012) Fuyong Du   Frontiers in Bioscience-Landmark

Functional recovery after ischemic stroke--A matter of age: Data from the Austrian Stroke Unit Registry

(2012) M. Knoflach et al.   NEUROLOGY

Current and future treatments for Alzheimer’s disease

(2012) Konstantina G. Yiannopoulou et al.   Therapeutic Advances in Neurological Disorders

Functional recovery in aging mice after experimental stroke

(2011) Bharti Manwani et al.   BRAIN BEHAVIOR AND IMMUNITY

Hypoxia-induced angiogenesis is delayed in aging mouse brain

(2011) Girriso F. Benderro et al.   BRAIN RESEARCH

Immunoaging induced by hematopoietic stem cell aging

(2011) Jianwei Wang et al.   CURRENT OPINION IN IMMUNOLOGY

Quantitative MRI Reveals the Elderly Ischemic Brain is Susceptible to Increased Early Blood—Brain Barrier Permeability Following Tissue Plasminogen Activator Related to Claudin 5 and Occludin Disassembly

(2011) Jaspreet Kaur et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Predictors of Early and Late Case-Fatality in a Nationwide Danish Study of 26 818 Patients With First-Ever Ischemic Stroke

(2011) Klaus Kaae Andersen et al.   STROKE

Age-dependent alterations of monocyte subsets and monocyte-related chemokine pathways in healthy adults

(2010) Sebastian Seidler et al.   BMC IMMUNOLOGY

Dynamic perfusion-CT assessment of early changes in blood brain barrier permeability of acute ischaemic stroke patients

(2010) J.W. Dankbaar et al.   JOURNAL OF NEURORADIOLOGY

Monocytes in atherosclerosis: subsets and functions

(2010) Kevin J. Woollard et al.   Nature Reviews Cardiology

Review: Cerebral microvascular pathology in ageing and neurodegeneration

(2010) W. R. Brown et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion

(2010) I. Beerman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endothelial progenitor cell transplantation improves long-term stroke outcome in mice

(2009) Yongfeng Fan et al.   ANNALS OF NEUROLOGY

The Poor Outcome of Ischemic Stroke in Very Old People: A Cohort Study of Its Determinants

(2009) Licia Denti et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Age-related alterations in innate immune receptor expression and ability of macrophages to respond to pathogen challenge in vitro

(2009) Shuang Liang et al.   MECHANISMS OF AGEING AND DEVELOPMENT

A Randomized Trial of Rosuvastatin in the Prevention of Venous Thromboembolism

(2009) Robert J. Glynn et al.   NEW ENGLAND JOURNAL OF MEDICINE

Attenuation of Brain Response to Vascular Endothelial Growth Factor-Mediated Angiogenesis and Neurogenesis in Aged Mice

(2009) Peng Gao et al.   STROKE

A new mechanism for the aging of hematopoietic stem cells: aging changes the clonal composition of the stem cell compartment but not individual stem cells

(2008) R. H. Cho et al.   BLOOD

Altered morphology and 3D architecture of brain vasculature in a mouse model for Alzheimer's disease

(2008) E. P. Meyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Early disruptions of the blood–brain barrier may contribute to exacerbated neuronal damage and prolonged functional recovery following stroke in aged rats

(2007) Vincent A. DiNapoli et al.   NEUROBIOLOGY OF AGING