Metabolite secretion in microorganisms: the theory of metabolic overflow put to the test

Microbial interactions: ecology in a molecular perspective

(2016) Raíssa Mesquita Braga et al.   BRAZILIAN JOURNAL OF MICROBIOLOGY

Yeast toxicogenomics: lessons from a eukaryotic cell model and cell factory

(2015) Sandra C dos Santos et al.   CURRENT OPINION IN BIOTECHNOLOGY

Metabolic interactions in microbial communities: untangling the Gordian knot

(2015) Olga Ponomarova et al.   CURRENT OPINION IN MICROBIOLOGY

Can we predict the intracellular metabolic state of a cell based on extracellular metabolite data?

(2015) Ninna Granucci et al.   Molecular BioSystems

MetDFBA: incorporating time-resolved metabolomics measurements into dynamic flux balance analysis

(2015) A. Marcel Willemsen et al.   Molecular BioSystems

Model-driven discovery of underground metabolic functions inEscherichia coli

(2015) Gabriela I. Guzmán et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane transporter engineering in industrial biotechnology and whole cell biocatalysis

(2015) Douglas B. Kell et al.   TRENDS IN BIOTECHNOLOGY

Analysis of the yeast short-term Crabtree effect and its origin

(2014) Arne Hagman et al.   FEBS Journal

Prediction of intracellular metabolic states from extracellular metabolomic data

(2014) Maike K. Aurich et al.   Metabolomics

Exometabolome analysis reveals hypoxia at the up-scaling of a Saccharomyces cerevisiae high-cell density fed-batch biopharmaceutical process

(2014) Zhibiao Fu et al.   Microbial Cell Factories

Passive Lipoidal Diffusion and Carrier-Mediated Cell Uptake Are Both Important Mechanisms of Membrane Permeation in Drug Disposition

(2014) Dennis Smith et al.   MOLECULAR PHARMACEUTICS

Coordination of microbial metabolism

(2014) Victor Chubukov et al.   NATURE REVIEWS MICROBIOLOGY

Network-level architecture and the evolutionary potential of underground metabolism

(2014) R. A. Notebaart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic Metabolic Footprinting Reveals the Key Components of Metabolic Network in YeastSaccharomyces cerevisiae

(2014) Pramote Chumnanpuen et al.   International Journal of Genomics

MFS transporters required for multidrug/multixenobiotic (MD/MX) resistance in the model yeast: understanding their physiological function through post-genomic approaches

(2014) Sandra C. dos Santos et al.   Frontiers in Physiology

Glutamate efflux mediated by Corynebacterium glutamicum MscCG, Escherichia coli MscS, and their derivatives

(2013) Michael Becker et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Repetitive succinic acid production from lignocellulose hydrolysates by enhancement of ATP supply in metabolically engineered Escherichia coli

(2013) Liya Liang et al.   BIORESOURCE TECHNOLOGY

Current topics in the biotechnological production of essential amino acids, functional amino acids, and dipeptides

(2013) Satoshi Mitsuhashi   CURRENT OPINION IN BIOTECHNOLOGY

Basic and applied uses of genome-scale metabolic network reconstructions of Escherichia coli

(2013) D. McCloskey et al.   Molecular Systems Biology

Pyrimidine homeostasis is accomplished by directed overflow metabolism

(2013) Marshall Louis Reaves et al.   NATURE

Metabolic Response of Candida albicans to Phenylethyl Alcohol under Hyphae-Inducing Conditions

(2013) Ting-Li Han et al.   PLoS One

Metabolic Footprint Analysis Uncovers Strain Specific Overflow Metabolism and D-Isoleucine Production of Staphylococcus Aureus COL and HG001

(2013) Kirsten Dörries et al.   PLoS One

Synthesis, Release, and Recapture of Compatible Solute Proline by Osmotically Stressed Bacillus subtilis Cells

(2012) Tamara Hoffmann et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Improving metabolic flux predictions using absolute gene expression data

(2012) Dave Lee et al.   BMC Systems Biology

Redox balance is key to explaining full vs. partial switching to low-yield metabolism

(2012) Milan JA van Hoek et al.   BMC Systems Biology

Regulation of Amino Acid, Nucleotide, and Phosphate Metabolism in Saccharomyces cerevisiae

(2012) P. O. Ljungdahl et al.   GENETICS

Yeast Aquaglyceroporins Use the Transmembrane Core to Restrict Glycerol Transport

(2012) Cecilia Geijer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extensive exometabolome analysis reveals extended overflow metabolism in various microorganisms

(2012) Nicole Paczia et al.   Microbial Cell Factories

Solvent tolerance in Gram-negative bacteria

(2011) Ana Segura et al.   CURRENT OPINION IN BIOTECHNOLOGY

Corynebacterium glutamicum as a Host for Synthesis and Export of D-Amino Acids

(2011) N. Stabler et al.   JOURNAL OF BACTERIOLOGY

Identification of succinate exporter in Corynebacterium glutamicum and its physiological roles under anaerobic conditions

(2011) Keita Fukui et al.   JOURNAL OF BIOTECHNOLOGY

A genome-wide screen identifies yeast genes required for protection against or enhanced cytotoxicity of the antimalarial drug quinine

(2011) Sandra C. dos Santos et al.   MOLECULAR GENETICS AND GENOMICS

A comprehensive genome-scale reconstruction of Escherichia coli metabolism--2011

(2011) J. D. Orth et al.   Molecular Systems Biology

Ligand-gated diffusion across the bacterial outer membrane

(2011) B. W. Lepore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Yeast Fps1 glycerol facilitator functions as a homotetramer

(2011) Sara E. Beese-Sims et al.   YEAST

The structural basis of secondary active transport mechanisms

(2010) Lucy R. Forrest et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The properties and contribution of the Corynebacterium glutamicum MscS variant to fine-tuning of osmotic adaptation

(2010) Kirsten Börngen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Systems biology approach reveals that overflow metabolism of acetate in Escherichia coli is triggered by carbon catabolite repression of acetyl-CoA synthetase

(2010) Kaspar Valgepea et al.   BMC Systems Biology

Genome-scale metabolic analysis of Clostridium thermocellum for bioethanol production

(2010) Seth B Roberts et al.   BMC Systems Biology

Membrane Topology Analysis of the Escherichia coli Aromatic Amino Acid Efflux Protein YddG

(2010) Larisa G. Airich et al.   JOURNAL OF MOLECULAR MICROBIOLOGY AND BIOTECHNOLOGY

Metabolic footprint analysis of recombinant Escherichia coli strains during fed-batch fermentations

(2010) Sónia Carneiro et al.   Molecular BioSystems

What is flux balance analysis?

(2010) Jeffrey D Orth et al.   NATURE BIOTECHNOLOGY

Structural perspectives on secondary active transporters

(2010) Olga Boudker et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Connecting extracellular metabolomic measurements to intracellular flux states in yeast

(2009) Monica L Mo et al.   BMC Systems Biology

Predicting Metabolic Fluxes Using Gene Expression Differences As Constraints

(2009) Rogier J P van Berlo et al.   IEEE-ACM Transactions on Computational Biology and Bioinformatics

Development and experimental verification of a genome-scale metabolic model for Corynebacterium glutamicum

(2009) Yohei Shinfuku et al.   Microbial Cell Factories

Shifts in growth strategies reflect tradeoffs in cellular economics

(2009) Douwe Molenaar et al.   Molecular Systems Biology

Metabolic Control Analysis: A Tool for Designing Strategies to Manipulate Metabolic Pathways

(2008) Rafael Moreno-Sánchez et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Phenotypic characterization of transposon-inserted mutants of Clostridium proteoclasticum B316T using extracellular metabolomics

(2008) Silas G. Villas-Bôas et al.   JOURNAL OF BIOTECHNOLOGY

Central carbon metabolism ofSaccharomyces cerevisiaein anaerobic, oxygen-limited and fully aerobic steady-state conditions and following a shift to anaerobic conditions

(2007) Marilyn G. Wiebe et al.   FEMS YEAST RESEARCH