Exometabolome analysis reveals hypoxia at the up-scaling of a Saccharomyces cerevisiae high-cell density fed-batch biopharmaceutical process

Effect of culture medium, host strain and oxygen transfer on recombinant Fab antibody fragment yield and leakage to medium in shaken E. coli cultures

(2013) Kaisa Ukkonen et al.   Microbial Cell Factories

Optimization of a Saccharomyces cerevisiae fermentation process for production of a therapeutic recombinant protein using a multivariate bayesian approach

(2012) Zhibiao Fu et al.   BIOTECHNOLOGY PROGRESS

Extensive exometabolome analysis reveals extended overflow metabolism in various microorganisms

(2012) Nicole Paczia et al.   Microbial Cell Factories

Novel approach of high cell density recombinant bioprocess development: Optimisation and scale-up from microlitre to pilot scales while maintaining the fed-batch cultivation mode of E. coli cultures

(2010) Juozas Šiurkus et al.   Microbial Cell Factories

Low oxygen levels as a trigger for enhancement of respiratory metabolism in Saccharomyces cerevisiae

(2009) Eija Rintala et al.   BMC GENOMICS

Microbial factories for recombinant pharmaceuticals

(2009) Neus Ferrer-Miralles et al.   Microbial Cell Factories

Developing a scalable model of recombinant protein yield from Pichia pastoris: the influence of culture conditions, biomass and induction regime

(2009) William J Holmes et al.   Microbial Cell Factories

Mechanistic role of ergosterol in membrane rigidity and cycloheximide resistance in Saccharomyces cerevisiae

(2008) Fumiyoshi Abe et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

High cell density media for Escherichia coli are generally designed for aerobic cultivations – consequences for large-scale bioprocesses and shake flask cultures

(2008) Jaakko Soini et al.   Microbial Cell Factories