CD38 Deficiency Promotes Inflammatory Response through Activating Sirt1/NF-κB-Mediated Inhibition of TLR2 Expression in Macrophages

CD38 promotes angiotensin II-induced cardiac hypertrophy

(2017) Xiao-Hui Guan et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

CD38 deficiency suppresses adipogenesis and lipogenesis in adipose tissues through activating Sirt1/PPARγ signaling pathway

(2017) Ling-Fang Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The Nuclear Receptor LXR Limits Bacterial Infection of Host Macrophages through a Mechanism that Impacts Cellular NAD Metabolism

(2017) Jonathan Matalonga et al.   Cell Reports

Lysosomal cholesterol accumulation in macrophages leading to coronary atherosclerosis in CD38−/−mice

(2016) Xiaoyang Xu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

CD38 Deficiency Protects the Heart from Ischemia/Reperfusion Injury through Activating SIRT1/FOXOs-Mediated Antioxidative Stress Pathway

(2016) Xiao-Hui Guan et al.   Oxidative Medicine and Cellular Longevity

Role of CD38 Expression in Diagnosis and Pathogenesis of Chronic Lymphocytic Leukemia and Its Potential as Therapeutic Target

(2015) Simone Burgler   CRITICAL REVIEWS IN IMMUNOLOGY

The TLR2 is activated by sporozoites and suppresses intrahepatic rodent malaria parasite development

(2015) Hong Zheng et al.   Scientific Reports

CD38 Controls the Innate Immune Response against Listeria monocytogenes

(2013) Timo Lischke et al.   INFECTION AND IMMUNITY

CRISPR interference (CRISPRi) for sequence-specific control of gene expression

(2013) Matthew H Larson et al.   Nature Protocols

Transcription factor NFκB regulates the expression of the histone deacetylase SIRT1

(2013) Judith Katto et al.   Clinical Epigenetics

Evolving Bacterial Envelopes and Plasticity of TLR2-Dependent Responses: Basic Research and Translational Opportunities

(2013) Junbin Li et al.   Frontiers in Immunology

Interleukin-6 signaling pathway in targeted therapy for cancer

(2012) Yuqi Guo et al.   CANCER TREATMENT REVIEWS

Mice Deficient in CD38 Develop an Attenuated Form of Collagen Type II-Induced Arthritis

(2012) Jorge Postigo et al.   PLoS One

After the grape rush: Sirtuins as epigenetic drug targets in neurodegenerative disorders

(2011) Kilian Huber et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Association of polymorphisms in TLR genes and in genes of the Toll-like receptor signaling pathway with cancer risk

(2011) Anton G. Kutikhin   HUMAN IMMUNOLOGY

Acetylation-Deacetylation of the Transcription Factor Nrf2 (Nuclear Factor Erythroid 2-related Factor 2) Regulates Its Transcriptional Activity and Nucleocytoplasmic Localization

(2011) Yumiko Kawai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Absence of CD38 delays arrival of neutrophils to the liver and innate immune response development during hepatic amoebiasis by Entamoeba histolytica

(2011) L. A. ESTRADA-FIGUEROA et al.   PARASITE IMMUNOLOGY

Pattern Recognition Receptors and the Innate Immune Response to Viral Infection

(2011) Mikayla R. Thompson et al.   Viruses-Basel

Polymerization of MIP-1 chemokine (CCL3 and CCL4) and clearance of MIP-1 by insulin-degrading enzyme

(2010) Min Ren et al.   EMBO JOURNAL

The Unique Transcriptional Activation Domain of Nuclear Factor-I-X3 Is Critical to Specifically Induce Marker Gene Expression in Astrocytes

(2010) Sandeep K. Singh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Ecto-enzyme CD38 Is a Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) Synthase That Couples Receptor Activation to Ca2+Mobilization from Lysosomes in Pancreatic Acinar Cells

(2010) François Cosker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release

(2010) H. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Monocyte Chemoattractant Protein-1 (MCP-1): An Overview

(2009) Satish L. Deshmane et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Toll-like receptor 2 ligands on the staphylococcal cell wall downregulate superantigen-induced T cell activation and prevent toxic shock syndrome

(2009) Thu A Chau et al.   NATURE MEDICINE

Signaling mechanisms involved in altered function of macrophages from diet-induced obese mice affect immune responses

(2009) Q. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toll-like receptor polymorphisms and susceptibility to human disease

(2008) E. Ann Misch et al.   CLINICAL SCIENCE

Polymorphisms in Toll-like receptor genes and risk of cancer

(2008) E M El-Omar et al.   ONCOGENE

Characterization of brain inflammation during primary amoebic meningoencephalitis

(2008) Isaac Cervantes-Sandoval et al.   PARASITOLOGY INTERNATIONAL

Evolution and Function of the ADP Ribosyl Cyclase/CD38 Gene Family in Physiology and Pathology

(2008) Fabio Malavasi et al.   PHYSIOLOGICAL REVIEWS