Article
Chemistry, Multidisciplinary
Susobhan Das, Subhankar Saha, Mrinmay Sahu, Amit Mondal, C. Malla Reddy
Summary: This study presents a rare example of a dynamic crystal involving the heavy transition metal rhenium, displaying initial two-face elasticity and elasto-plastic deformation at room temperature, followed by transformation into a rotator crystal phase at approximately 105 degrees C. The mechanical tests, X-ray diffraction, mu-Raman, and polarized light microscopy experiments reveal that the elasto-plastic deformation involves molecular rotations and slip, while malleability in the rotator phase is facilitated by reorientational motions and increased symmetry. Connecting plastically bendable crystals with rotator phases is important for designing multi-functional dynamic crystals.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Engineering, Environmental
Yanping Zhang, Alice Le Friec, Di Sun, Menglin Chen
Summary: The development of flexible electronics with adjustable performance offers a promising approach for treating cardiac diseases, overcoming the limitations of conventional electronic systems due to biomechanical mismatches. By exploring the natural flow behavior of polymer melt in Melt electrowriting (MEW), researchers created a fibrous mesh electrode with a sinusoidal anisotropic structure resembling the collagen fiber architecture in the heart. This anisotropic, stretchable electrode mesh demonstrated the ability to synchronize cardiomyocyte beating through its biomimetic viscoelastic behavior and fine-tuned electrical properties, offering great potential for cardiac repair.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Materials Science, Multidisciplinary
Fatimah Ibrahim, Aung Thiha, Wan Safwani Wan Kamarul Zaman, Yusniza Kamarulzaman, Nuraina Anisa Dahlan, Nurul Fauzani Jamaluddin, Marc J. Madou
Summary: This review introduces different microscaffold patterns and their technological applications in cardiac tissue engineering, as well as discusses the desirable scaffold properties. A comparative analysis of six micropatterning technologies on the development of cardiac scaffolds is presented.
MATERIALS TODAY COMMUNICATIONS
(2022)
Article
Materials Science, Multidisciplinary
Jinjie Wu, Rongfeng Zhang, Yang Li, Xiupeng Zhu, Xuening Chen, Jie Weng, Wei Zhi, Jianxin Wang, Zhao Xie, Xingdong Zhang
Summary: Bone tissue engineering is a potential strategy in treating bone defects, but implantation failure caused by cell death has been a challenge. This study presents a method to construct dynamically functional bone grafts using mechanical field drive-coupling and mechanobiology theory, enhancing bone regeneration ability by optimizing the osteogenic microenvironment and cell functional activity.
APPLIED MATERIALS TODAY
(2022)
Review
Engineering, Biomedical
Huaiyu Shi, Chenyan Wang, Zhen Ma
Summary: Stimuli-responsive biomaterials have been utilized as powerful tools in tissue engineering, mechanobiology, and clinical applications since the 1980s. These materials are able to fabricate hydrogels and nanoparticles for targeted delivery of therapeutic drugs and cells, aiding in disease alleviation and tissue regeneration. By mimicking the dynamic microenvironment of the native heart, stimuli-responsive biomaterials can also help in understanding cardiac cells and tissues response to changes in extracellular microenvironments for dynamic cell mechanobiology investigation.
APL BIOENGINEERING
(2021)
Article
Biochemistry & Molecular Biology
Aurelia Poerio, Bertrand Guibert, Melanie M. Leroux, Joao F. Mano, Franck Cleymand, Jean-Philippe Jehl
Summary: Myocardial infarction can cause irreversible damage to the heart muscle. Using 3D printing and a biomaterial ink, a study developed patterned anisotropic membranes that mimic the fibrillar structure of the myocardium, which could be used as cardiac patches for treatment and prevention of complications. A numerical model was also developed to predict the elastic properties of different geometries with tunable elasticity that can match the mechanical properties of the heart tissue.
Review
Chemistry, Multidisciplinary
Ilaria Roato, Beatrice Masante, Giovanni Putame, Diana Massai, Federico Mussano
Summary: This review provides an overview of recent advancements in periodontal tissue engineering, focusing on the use of PDLSCs and 3D scaffolds. The findings demonstrate the potential of these methods for innovative therapies in the future.
Article
Engineering, Multidisciplinary
David Sergeevichev, Maria Vasiliyeva, Elena Kuznetsova, Boris Chelobanov
Summary: Widely used storage methods, including freezing or chemical modification, degrade the mechanical properties of heart valve prostheses. Wet storage using biocidal solutions showed no significant effect on the material strength and elastic properties of native and decellularized porcine aorta and pulmonary trunk. The wet storage protocol using alcohol solutions may be intended for further fabrication of tissue-engineered biological heart valve prostheses.
Review
Biotechnology & Applied Microbiology
Hussein M. El-Husseiny, Eman A. Mady, Walaa A. El-Dakroury, Ahmed S. Doghish, Ryou Tanaka
Summary: Recent advancements in biomedicine and tissue regeneration have had a positive impact on healthcare as a whole, particularly in the field of revitalizing damaged tissues. Cardiac tissue engineering (CTE) using biomolecules, biomimetic scaffolds, and cells is crucial in this process. Stimuli-responsive hydrogels (SRHs) are excellent biomaterials for tissue engineering, as they can mimic the characteristics of natural tissues and act as effective delivery platforms. This review outlines various strategies used in CTE, highlights the limitations of conventional hydrogels, and discusses the characteristics, assembly, and exploitation of SRHs in CTE. Overall, the development of SRHs holds great potential for the reconstruction of degenerated cardiac tissues.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Review
Chemistry, Multidisciplinary
Durga Prasad Karothu, Jad Mahmoud Halabi, Ejaz Ahmed, Rodrigo Ferreira, Peter R. Spackman, Mark A. Spackman, Pance Naumov
Summary: This paper summarizes the mechanical properties of organic crystals over the past three decades and establishes a global mechanical property profile. Organic crystals occupy a specific region in the mechanical property-density space and can be used to predict and identify mechanically robust organic crystal materials.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Chemistry, Applied
Penghui Wang, Yajie Pu, Yanhan Ren, Rong Yang, Wenjie Zhang, Xiaoyan Tan, Wenliang Xue, Shuai Liu, Shuang Li, Bo Chi
Summary: This research introduces a novel hybrid hydrogel system based on sodium alginate and polyglutamic acid, with adjustable gelation time and mechanical strength, prolonged degradation time and reduced swelling rate, dynamic response characteristics, excellent self-healing and injectable ability. The system shows positive cytocompatibility and accelerated regulatory gene expression in cartilage tissue, indicating broad application prospects in future biomedical engineering.
CARBOHYDRATE POLYMERS
(2022)
Review
Polymer Science
Kaylee Meyers, Bruce P. Lee, Rupak M. Rajachar
Summary: Myocardial infarction can cause permanent damage to the heart, leading to cardiac failure. Current transplantation methods face issues such as donor shortages and complications. Polymeric scaffolds offer an alternative, but mechanical property mismatch and limited electrical conductivity are challenges to be addressed for clinical applicability.
Review
Nanoscience & Nanotechnology
Mingyu Lee, Min Chul Kim, Jae Young Lee
Summary: Cardiovascular disease is a leading cause of death, and biomaterial-based tissue engineering approaches have shown promise in cardiac repair. This review focuses on the use of nanomaterial-incorporated conductive hydrogels for improving cardiac function post-myocardial infarction.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2022)
Article
Engineering, Biomedical
Zebin Wu, Qiao Li, Lizhen Wang, Yang Zhang, Wei Liu, Shudong Zhao, Xuezheng Geng, Yubo Fan
Summary: In this study, a novel biocompatible fibrous scaffold with tunable mechanical and electrical properties was successfully prepared by blending PGS and PANI materials. These scaffolds promote cell adhesion and proliferation, exhibit good biocompatibility and hemocompatibility, and have great potential for cardiac tissue engineering.
MATERIALS TODAY BIO
(2023)
Review
Biochemistry & Molecular Biology
Karine Tadevosyan, Olalla Iglesias-Garcia, Manuel M. Mazo, Felipe Prosper, Angel Raya
Summary: Cardiac tissue engineering is a promising strategy for cardiac disease modeling, cardiotoxicity testing, and cardiovascular repair, but challenges remain in replicating tissue-like properties and in assessing functionality and maturation state. Progress has been made in the field over the last two decades, but there is still a need for a unified framework for comparison of engineered cardiac tissue constructs generated using different methodologies.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Materials Science, Multidisciplinary
Zhida Liang, Jonathan D. H. Paul, Andreas Stark, Andreas Bezold, Steffen Neumeier, Mathias Goeken, Florian Pyczak
Summary: Recent research has explored the Co-Al-W system and revealed interesting properties, but its high tungsten content limits industrial applications. As a result, new high temperature superalloys based on the Co-Ni-Al-Ti system, strengthened by chromium and different refractory elements, have been developed. These alloys exhibit better mechanical properties at high temperatures compared to conventional Ni-based superalloys and Co-based superalloys.
METALLURGICAL AND MATERIALS TRANSACTIONS A-PHYSICAL METALLURGY AND MATERIALS SCIENCE
(2023)
Article
Materials Science, Multidisciplinary
Waseem Kitana, Indra Apsite, Jonas Hazur, Aldo R. Boccaccini, Leonid Ionov
Summary: This study reports a 4D biofabrication-based concept for the fabrication of a T-shaped vascular bifurcation using 3D printed shape-changing layers. The tubular structures with various diameters were formed by controlling the parameters precisely. The fabricated T-junction showed minimal leakages and supported excellent cell growth. This approach has the potential to fabricate fully automatic self-actuated vascular bifurcations.
ADVANCED MATERIALS TECHNOLOGIES
(2023)
Article
Engineering, Biomedical
A. Weizel, T. Distler, R. Detsch, A. R. Boccaccini, H. Seitz, S. Budday
Summary: Numerical simulations using appropriate material models and parameters are valuable for understanding the effects of mechanical stimulation on hydrogels for cartilage replacement. In this study, hyperviscoelastic material parameters for human articular cartilage and two replacement materials were identified using COMSOL Multiphysics (R) v. 5.6. The results revealed that ADA-GEL and ChondroFiller(liquid) exhibit faster stress relaxation and lower relaxation time constants compared to cartilage. Additionally, ADA-GEL and ChondroFiller(liquid) have a predominant elastic response, while cartilage has a predominant viscoelastic response.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2023)
Article
Nanoscience & Nanotechnology
Baiyan Sui, Zhiyan Xu, Zhiyu Xue, Yong Xiang, Tian Zhou, Ana M. Beltraïn, Kai Zheng, Xin Liu, Aldo R. Boccaccini
Summary: A postgrafting strategy mediated by polydopamine (PDA) coating is proposed to incorporate different metal elements into mesoporous silicate bioactive glass nanoparticles (MBG NPs) while maintaining their stability. However, the PDA coating reduces the ion-binding free energy of MBG NPs for calcium and phosphate ions, resulting in minimal deposition of calcium phosphate clusters on the PDA@MBG NP surface after immersion in simulated body fluid for 7 days, indicating a lack of hydroxyapatite mineralization.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Nanoscience & Nanotechnology
Mahshid Monavari, Shahin Homaeigohar, Rucha Medhekar, Qaisar Nawaz, Mehran Monavari, Kai Zheng, Aldo R. Boccaccini
Summary: In this study, a wound dressing composed of an alginate dialdehyde-gelatin (ADA-GEL) hydrogel incorporated by astaxanthin (ASX) and 70B borate bioactive glass (BBG) microparticles was developed through 3D printing. The composite hydrogel construct, stiffened by ASX and BBG particles, showed prolonged degradation and steady release of ASX, promoting cell adhesion, proliferation, and migration for faster wound healing.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Review
Engineering, Biomedical
Florencia Diaz, Nicholas Forsyth, Aldo R. Boccaccini
Summary: This review evaluates the work done in the last decade toward the production of aligned pore structures by AIT, focusing on optimizing the biomechanical properties by modifying the pore structure, categorizing by material type and application. The review also discusses related topics including growth factor incorporation, drug delivery applications, and immune system response studies.
ADVANCED HEALTHCARE MATERIALS
(2023)
Article
Polymer Science
Arturo E. Aguilar-Rabiela, Shahin Homaeigohar, Eduin I. Gonzalez-Castillo, Mirna L. Sanchez, Aldo R. Boccaccini
Summary: Composite biomaterials combining different biomaterials with unequal release rates have shown potential for drug delivery applications. In this study, mesoporous bioactive glass nanoparticles (MBGN) and poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) microspheres loaded with Astaxanthin (ASX) were synthesized and compared in terms of ASX release kinetic, ASX entrapment efficiency, and cell viability. The release behavior could be fine-tuned by adjusting the MBGN content in the composite particles, and the composite microspheres exhibited a more prolonged release profile with sustained cytocompatibility.
Article
Polymer Science
Iskenderbek Elchiev, Gokhan Demirci, Miroslawa El Fray
Summary: Photocurable biomaterials that can be rapidly cured using UV light are becoming popular in advanced medical applications. By modifying the structure of coumarin and combining it with a bio-based fatty acid dimer derivative, we designed a dynamic network that can crosslink and re-crosslink under variable wave lengths of UV light. This biomaterial can be injected and cured in situ upon UV light exposure, making it suitable for future medical applications.
Article
Biochemistry & Molecular Biology
Marta Clerici, Vera Citro, Amy L. Byrne, Tina P. Dale, Aldo R. Boccaccini, Giovanna Della Porta, Nicola Maffulli, Nicholas R. Forsyth
Summary: By comparing and contrasting different tendon cell populations, this study found that type II tendon stem cells (TSCs) are the most promising population for expansion due to their enhanced proliferative potential, multipotency, and maintenance of a tendon-specific profile. Furthermore, physoxia promotes enhanced proliferation and maintenance of a tenogenic profile in all tendon-derived cell populations.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Biotechnology & Applied Microbiology
Yuyun Yang, Yuejun Liu, Laiming Song, Xiufang Cui, Juncen Zhou, Guo Jin, Aldo R. Boccaccini, Sannakaisa Virtanen
Summary: Iron-oxide-based biomagnetic nanocomposites have significant potential for biomedical applications such as MRI and cancer treatment. By modifying their properties and structure, their performance can be optimized. However, rigorous evaluation of their biosafety is needed before clinical translation.
TRENDS IN BIOTECHNOLOGY
(2023)
Article
Materials Science, Composites
Mohamed S. Hasanin, Yasser Elhenawy, Shereen M. S. Abdel-Hamid, Yasser Fouad, Toderas Monica, O. A. Al-Qabandi, Miroslawa El Fray, Mohamed Bassyouni
Summary: In this study, a novel nanocomposite formulation was developed using biopolymers as capping and stabilizing agents to create bimetallic nanoparticles. The obtained characteristics showed the presence of a nanostructure involving bimetallic nanoparticles. The formulation exhibited excellent biological activity, including high biocompatibility and effective anticancer and antimicrobial activities, as well as antioxidant activity.
JOURNAL OF COMPOSITES SCIENCE
(2023)
Article
Biotechnology & Applied Microbiology
Jana Schulik, Sahar Salehi, Aldo R. Boccaccini, Stefan Schruefer, Dirk W. Schubert, Andreas Arkudas, Annika Kengelbach-Weigand, Raymund E. Horch, Rafael Schmid
Summary: This study compared the mechanical properties and the behavior of human umbilical vein endothelial cells (HUVECs) in three hydrogels (Alg/HA/Gel, ADA-GEL, and GelMA) for vascular tissue engineering. ADA-GEL and GelMA showed promising results for cell survival, migration, and sprouting, while Alg/HA/Gel did not provide a good environment for long-term survival of HUVECs.
BIOENGINEERING-BASEL
(2023)
Article
Nanoscience & Nanotechnology
Shahin Homaeigohar, Mhd Adel Assad, Amir Hossein Azari, Farnaz Ghorbani, Chloe Rodgers, Matthew J. Dalby, Kai Zheng, Rongyao Xu, Mady Elbahri, Aldo. R. Boccaccini
Summary: The biohybrid nanofibers developed in this study can stimulate the adhesion and proliferation of fibroblast and endothelial cells, showing potential for promoting wound healing and antibacterial activity.
ACS APPLIED BIO MATERIALS
(2023)
Article
Materials Science, Ceramics
Susanta Sengupta, Liliana Liverani, Dusan Galusek, Aldo R. Boccaccini
Summary: Borosilicate glass fibers fabricated by electrospinning in combination with sol-gel processing showed good bioactivity and non-cytotoxic nature in simulated body fluid.
Article
Materials Science, Ceramics
Q. Nawaz, A. de Pablos-Martin, A. T. Contreras Jaimes, F. Scheffler, T. Wagner, D. S. Brauer, A. R. Boccaccini
Summary: This study compares the properties of scaffolds prepared using sol-gel and melt-derived powders. The microstructure, shrinkage behavior, bioactivity, and cell compatibility of the scaffolds were evaluated. The findings show that sol-gel derived 13-93 scaffolds exhibit similar characteristics to melt-derived scaffolds, and the sol-gel approach offers advantages such as low temperature processing and high purity for fabricating high-quality scaffolds.
Article
Materials Science, Multidisciplinary
Deyong Zheng, Huihui Jin, Yucong Liao, Pengxia Ji
Summary: In this study, a highly stable and efficient catalyst, fluorine-doped Co3O4 (F-Co3O4), was developed for hydrogen production by water electrolysis. The F-Co3O4 catalyst exhibited a remarkable reduction in overpotential and demonstrated excellent stability for over 100 hours.
Article
Materials Science, Multidisciplinary
Ziwen Lv, Jintao Wang, Fengyi Wang, Jianqiang Wang, Fuquan Li, Hongtao Chen
Summary: Adding Cu6Sn5 nano particles can effectively inhibit the overgrowth of intermetallic compounds at the interfaces of solder joints in electronic devices, providing a solution to this issue. A new growth mechanism of intermetallic compounds at the interfaces was identified.
Article
Materials Science, Multidisciplinary
Jun Wang, Jiawei Chen, Wanru Liao, Fangyang Liu, Min Liu, Liangxing Jiang
Summary: A BiOI/AgI/Ag plasmonic heterostructure photocathode was successfully designed through electrodeposition, ion-exchange, and illumination methods. This photocathode exhibits superior performance in photoelectrochemical water splitting.
Article
Materials Science, Multidisciplinary
Xiaoxiao Liu, Xianxian Zhou, Xiaotao Ma, Qinbo Yuan, Shibin Liu
Summary: In this study, the authors propose a method to accelerate the reaction of polysulfides in lithium-sulfur batteries using a Ni@OC Mott-Schottky heterojunction as a catalyst. The experimental results demonstrate that the charge redistribution at the Ni@OC interface accelerates electron transfer and enhances catalytic activity, leading to improved reaction kinetics and battery performance.
Article
Materials Science, Multidisciplinary
Dayou Ma, Mohammad Rezasefat, Joziel Aparecido da Cruz, Sandro Campos Amico, Marco Giglio, Andrea Manes
Summary: The matrix has a significant effect on the impact resistance of composite materials. Replacing a brittle polymer with a more flexible one can improve impact resistance, but it poses challenges to standard testing methods. This study designs a new fixture for testing the low-velocity impact of soft composites and investigates the effect of the fixture on the mechanical performance.
Article
Materials Science, Multidisciplinary
Lingchang Wang, Qihang Yang, Huzhen Li, Ming Wei, Qian Wang, Zhenzhong Hu, Mengmeng Zhen
Summary: Bronze titanium dioxide (TiO2(B)) is a promising anode material for lithium-ion batteries due to its high specific capacity. However, its practical applications are hindered by poor conductivity and limited electrochemical kinetics. In this study, TiO2(B)-carbon nanosheets heterostructures are synthesized to enhance the cycling performance and rate capability of TiO2(B).
Article
Materials Science, Multidisciplinary
Atul Thakur, Ritesh Verma, Ankush Chauhan, Fayu Wan, Preeti Thakur
Summary: In this study, BaFe12O19 and BaFe12O19: Epoxy (50:50) nanocomposites were synthesized using the co-precipitation method. The structural information and material properties, such as crystallite size and electrical conductivity, were characterized by XRD, FESEM, EDX, and TEM techniques.
Article
Materials Science, Multidisciplinary
Jingyu Wu, Xinyan Ma, Yong Yang
Summary: A well-defined CoS2@NC(CS-500) hierarchical binder-free catalyst cathode is constructed through in-situ grown of ZIF-67 on carbon cloth and high-temperature carbonization. The cathode shows excellent reaction kinetics and electrochemical performance, providing inspiration for developing advanced Li-CO2 battery catalysts.
Article
Materials Science, Multidisciplinary
Svetlana M. Posokhova, Vladimir A. Morozov, Kirill N. Boldyrev, Dina Deyneko, Erzhena T. Pavlova, Bogdan I. Lazoryak
Summary: This study explores the impact of synthesis method and composition on the structure and luminescence properties of K5Eu1-xHox(MoO4)4 with the palmierite-type matrix. The co-doping of Eu3+ and Ho3+ ions plays a critical role in manipulating charge transfer and luminescence efficiency in the visible and infrared regions.
Article
Materials Science, Multidisciplinary
Jian Wang, Yeting Tao, Jingsheng Wang, Youtian Tao
Summary: A new electron-transport material iTPyBI-CN is developed through non-catalytic C-N coupling reaction. It exhibits better electroluminescence efficiency in organic light-emitting diodes compared to the commercial material TPBI, due to its twisted geometry and higher energy levels.
Article
Materials Science, Multidisciplinary
Tao Zhu, Feng Huang, Shuo Li, Yang Zhou
Summary: This article combines XRD analysis and microscopic structural observation to investigate the changes in limestone after high-temperature treatment. It finds that 500 degrees C is the critical temperature for crystalline and spatial arrangement changes in limestone, and the thermal conductivity, specific heat capacity, and heat storage coefficient gradually decrease after thermal treatment.
Article
Materials Science, Multidisciplinary
Muhammad Haekal Habibie, Fransiska Sri Herwahyu Krismastuti, Abdi Wira Septama, Faiza Maryani, Vivi Fauzia
Summary: This study focuses on the synthesis of zinc oxide nanostructure from zinc recovered from galvanization ash and highlights its potential as a sustainable source of zinc and as an antibacterial agent.
Article
Materials Science, Multidisciplinary
Jingyi Li, Yixin Xing, Wei Gu, Shousi Lu
Summary: In this study, PC@CaP microparticles were fabricated using biomimetic mineralization. The results showed that under environmental stress, PC@CaP exhibited improved stability and antioxidative activity, indicating its potential use in high-added value fields.
Article
Materials Science, Multidisciplinary
Yan Liu, Shunyou Chen
Summary: In this study, TNTs were used as a drug carrier and modified with ZIF-8 and silk fibroin to obtain a new drug loading platform. The results showed that this drug-loaded platform had a good drug release effect in vitro and could promote cell proliferation and osteogenic differentiation.
Article
Materials Science, Multidisciplinary
Chunhui Zhu, Wentao Wang, Qing Zhen, Xinning Huang, Shixin Li, Shaochang Wang, Xiaoping Ma, Xiaoxia Liu, Yalong Jiao, Kai Sun, Zhuangzhi Li, Huaixin Yang, Jianqi Li
Summary: A type of stacking fault is revealed in e-InSe crystal, which is associated with a small stacking-fault energy and shows exceptional plasticity.
