Assessing Plasmodium falciparum transmission in mosquito-feeding assays using quantitative PCR

A controlled human malaria infection model enabling evaluation of transmission-blocking interventions

(2018) Katharine A. Collins et al.   JOURNAL OF CLINICAL INVESTIGATION

Safety, tolerability, pharmacokinetics, and activity of the novel long-acting antimalarial DSM265: a two-part first-in-human phase 1a/1b randomised study

(2017) James S McCarthy et al.   LANCET INFECTIOUS DISEASES

Semi-high-throughput detection of Plasmodium falciparum and Plasmodium vivax oocysts in mosquitoes using bead-beating followed by circumsporozoite ELISA and quantitative PCR

(2017) Wouter Graumans et al.   MALARIA JOURNAL

Concentration of Plasmodium falciparum gametocytes in whole blood samples by magnetic cell sorting enhances parasite infection rates in mosquito feeding assays

(2017) Isaie J. Reuling et al.   MALARIA JOURNAL

Evidence of multiple insecticide resistance mechanisms in Anopheles gambiae populations in Bangui, Central African Republic

(2017) Marina Lidwine Olé Sangba et al.   Parasites & Vectors

Examining the human infectious reservoir for Plasmodium falciparum malaria in areas of differing transmission intensity

(2017) Bronner P. Gonçalves et al.   Nature Communications

Probability of Transmission of Malaria from Mosquito to Human Is Regulated by Mosquito Parasite Density in Naïve and Vaccinated Hosts

(2017) Thomas S. Churcher et al.   PLoS Pathogens

Four human Plasmodium species quantification using droplet digital PCR

(2017) Suttipat Srisutham et al.   PLoS One

Pharmacokinetic/pharmacodynamic modelling of the antimalarial effect of Actelion-451840 in an induced blood stage malaria study in healthy subjects

(2016) Andreas Krause et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Efficacy of OZ439 (artefenomel) against earlyPlasmodium falciparumblood-stage malaria infection in healthy volunteers

(2016) James S. McCarthy et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Piperaquine Monotherapy of Drug-SusceptiblePlasmodium falciparumInfection Results in Rapid Clearance of Parasitemia but Is Followed by the Appearance of Gametocytemia

(2016) Cielo J. Pasay et al.   JOURNAL OF INFECTIOUS DISEASES

Routine in vitro culture of P. falciparum gametocytes to evaluate novel transmission-blocking interventions

(2016) Michael J Delves et al.   Nature Protocols

Utilizing direct skin feeding assays for development of vaccines that interrupt malaria transmission: A systematic review of methods and case study

(2016) Elizabeth B. Brickley et al.   VACCINE

Transmission-blocking activity is determined by transmission-reducing activity and number of control oocysts in Plasmodium falciparum standard membrane-feeding assay

(2016) Kazutoyo Miura et al.   VACCINE

Safety and Reproducibility of a Clinical Trial System Using Induced Blood Stage Plasmodium vivax Infection and Its Potential as a Model to Evaluate Malaria Transmission

(2016) Paul Griffin et al.   PLoS Neglected Tropical Diseases

Malaria: Global progress 2000 – 2015 and future challenges

(2016) Richard E. Cibulskis et al.   Infectious Diseases of Poverty

Sensitive and accurate quantification of human malaria parasites using droplet digital PCR (ddPCR)

(2016) Cristian Koepfli et al.   Scientific Reports

Evaluating the Pharmacodynamic Effect of Antimalarial Drugs in Clinical Trials by Quantitative PCR

(2015) Louise Marquart et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Experimental study of the relationship between Plasmodium gametocyte density and infection success in mosquitoes; implications for the evaluation of malaria transmission-reducing interventions

(2015) Dari F. Da et al.   EXPERIMENTAL PARASITOLOGY

A comparison of Plasmodium falciparum circumsporozoite protein-based slot blot and ELISA immuno-assays for oocyst detection in mosquito homogenates

(2015) Will Stone et al.   MALARIA JOURNAL

A Scalable Assessment of Plasmodium falciparum Transmission in the Standard Membrane-Feeding Assay, Using Transgenic Parasites Expressing Green Fluorescent Protein–Luciferase

(2014) Will J. R. Stone et al.   JOURNAL OF INFECTIOUS DISEASES

Malaria: a molecular marker of artemisinin resistance

(2014) Nicholas J White   LANCET

Molecular Characterization of the Carboxypeptidase B1 of Anopheles stephensi and Its Evaluation as a Target for Transmission-Blocking Vaccines

(2013) Abbasali Raz et al.   INFECTION AND IMMUNITY

Absolute quantification by droplet digital PCR versus analog real-time PCR

(2013) Christopher M Hindson et al.   NATURE METHODS

Multiple insecticide resistance mechanisms in Anopheles gambiae s.l. populations from Cameroon, Central Africa

(2013) Philippe Nwane et al.   Parasites & Vectors

Study of Mechanism of Interaction of Mercurochrome with CT-DNA by Computation, Fluorescence and Electrophoretic Methods

(2013) Rupali Sethi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES INDIA SECTION A-PHYSICAL SCIENCES

Transmission-blocking interventions eliminate malaria from laboratory populations

(2013) A. M. Blagborough et al.   Nature Communications

The relevance and applicability of oocyst prevalence as a read-out for mosquito feeding assays

(2013) Will J. R. Stone et al.   Scientific Reports

Geneious Basic: An integrated and extendable desktop software platform for the organization and analysis of sequence data

(2012) M. Kearse et al.   BIOINFORMATICS

Optimized Pan-species and Speciation Duplex Real-time PCR Assays for Plasmodium Parasites Detection in Malaria Vectors

(2012) Maurice Marcel Sandeu et al.   PLoS One

Can field-based mosquito feeding assays be used for evaluating transmission-blocking interventions?

(2012) Teun Bousema et al.   TRENDS IN PARASITOLOGY

Factors determining the occurrence of submicroscopic malaria infections and their relevance for control

(2012) Lucy C. Okell et al.   Nature Communications

Epidemiology and Infectivity of Plasmodium falciparum and Plasmodium vivax Gametocytes in Relation to Malaria Control and Elimination

(2011) T. Bousema et al.   CLINICAL MICROBIOLOGY REVIEWS

False positive circumsporozoite protein ELISA: a challenge for the estimation of the entomological inoculation rate of malaria and for vector incrimination

(2011) Lies Durnez et al.   MALARIA JOURNAL

A real-time, quantitative PCR method using hydrolysis probes for the monitoring of Plasmodium falciparum load in experimentally infected human volunteers

(2011) Rebecca J Rockett et al.   MALARIA JOURNAL

A Pilot Randomised Trial of Induced Blood-Stage Plasmodium falciparum Infections in Healthy Volunteers for Testing Efficacy of New Antimalarial Drugs

(2011) James S. McCarthy et al.   PLoS One

Validation of Laboratory-Developed Molecular Assays for Infectious Diseases

(2010) E. M. Burd   CLINICAL MICROBIOLOGY REVIEWS

A semi-automated method for counting fluorescent malaria oocysts increases the throughput of transmission blocking studies

(2010) Michael J Delves et al.   MALARIA JOURNAL

The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments

(2009) S. A. Bustin et al.   CLINICAL CHEMISTRY

Implementation of a novel PCR based method for detecting malaria parasites from naturally infected mosquitoes in Papua New Guinea

(2009) Arif U Hasan et al.   MALARIA JOURNAL

Evidence of Artemisinin-Resistant Malaria in Western Cambodia

(2008) Harald Noedl et al.   NEW ENGLAND JOURNAL OF MEDICINE

PlasmoDB: a functional genomic database for malaria parasites

(2008) C. Aurrecoechea et al.   NUCLEIC ACIDS RESEARCH

A novel gel-based method for self-collection and ambient temperature postal transport of urine for PCR detection of Chlamydia trachomatis

(2008) S Bialasiewicz et al.   SEXUALLY TRANSMITTED INFECTIONS

Conserved Mosquito/Parasite Interactions Affect Development of Plasmodium falciparum in Africa

(2008) Antonio M. Mendes et al.   PLoS Pathogens