Article
Construction & Building Technology
Bing Yin, Xianle Hua, Dongmei Qi, Kailu Han, Pan Wang, Dongshuai Hou, Chaohong Liu
Summary: This paper develops a continuous multi-scale synergistic modified cement-based material with excellent properties by using polymers, whiskers, and fibers. The flexural strength of the multi-scale modification samples is increased by more than 135% compared to the neat paste, while the 28d compressive strength is maintained essentially the same, with only a 2.9% reduction. This multi-scale modification strategy provides new ideas and promising applications for preparing high-performance cement-based materials.
CEMENT & CONCRETE COMPOSITES
(2023)
Article
Polymer Science
Minsik Choi, Junghwan Kim, Yuna Oh, Jaesang Yu, Sung-Gi Kim, Heejoun Yoo, Seongwoo Ryu, Nam-Ho You, Bon-Cheol Ku
Summary: Poly(phenylene sulfide) (PPS) grafting can be achieved by sulfur-assisted reduced graphene oxide (SrGO) via SNAr mechanism. The use of highly concentrated SrGO and masterbatch (MB) enhances the tensile strength, electrical and thermal conductivities, and flame retardancy of PPS-coated SrGO. Dilution of the MB in PPS resin results in finely distributed SrGO and preserves or enhances thermal conductivity and flame retardancy of PPS/SrGO.
Article
Chemistry, Multidisciplinary
Qingqing Zhou, Wen Wu, Tieling Xing
Summary: Research on the polymerization of dopamine and its modification on the surface of materials has been extensively studied. The study investigated the process of laccase catalyzing the rapid polymerization of dopamine and in situ dyeing of silk fabric. The results showed that laccase catalyzed dyeing under acidic conditions achieved the same effect as 24 hours of dyeing under alkaline conditions, and the enzyme-catalyzed polydopamine had better uniformity on the substrate surface. Molecular simulation analysis revealed the interaction between dopamine oligomers and silk fibroin, including hydrogen bonding and pi-pi stacking interactions. The modified silk fabrics exhibited good hydrophobicity after reacting with different metal salt solutions.
Article
Chemistry, Applied
Radoslava Sivkova, Jan Svoboda, Jiri Panek, Dietmar Appelhans, Ognen Pop-Georgievski
Summary: In this study, a method for initiating atom-transfer radical polymerization of active esters and post-polymerization modification was presented. The obtained active ester brushes showed complete conversion under amidation conditions with various primary amines. The effectiveness of the amidation reaction was studied using various techniques, and the resulting polymer brushes containing fluorophores were analyzed using fluorescent microscopy.
PROGRESS IN ORGANIC COATINGS
(2023)
Article
Polymer Science
Jon Lopez de Lacalle, Antonela Gallastegui, Jorge L. Olmedo-Martinez, Melissa Moya, Naroa Lopez-Larrea, Matias L. Picchio, David Mecerreyes
Summary: In this study, a novel family of deep eutectic monomers and corresponding polymers was reported. These polymers were made of (meth)acrylic ammonium salts and biobased polyphenols bearing catechol or pyrogallol motifs. The phenolic chemistry allowed the modulation of ionic polymer properties, resulting in adhesive or tough materials. Furthermore, the phenolic polymeric deep eutectic solvents (polyDES) exhibited metal complexation ability, antibacterial properties, and fast processability by digital light 3D printing.
Article
Nanoscience & Nanotechnology
Sadman Sakib, Amin Hosseini, Igor Zhitomirsky, Leyla Soleymani
Summary: The study presents a photoelectrochemical immunosensor for detecting IL-6 by utilizing catecholate-modified TiO2 photoelectrodes, achieving high sensitivity and signal-to-noise ratio enhancement.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Engineering, Manufacturing
Daniel J. Eyckens, Karyn Jarvis, Anders J. Barlow, Yanting Yin, Lachlan C. Soulsby, Y. Athulya Wickramasingha, Filip Stojcevski, Gunther Andersson, Paul S. Francis, Luke C. Henderson
Summary: This study demonstrates the combination of plasma and electrochemical treatments for enhancing the properties of carbon fibers. The combined treatment significantly increased tensile strength and fiber-to-matrix adhesion compared to control fibers and single treatment methods. Helium ion microscopy showed advantages over traditional SEM in visualizing non-conductive coatings on carbon fibers.
COMPOSITES PART A-APPLIED SCIENCE AND MANUFACTURING
(2021)
Article
Chemistry, Applied
Martina Zeljko, Sanja Lucic Blagojevic, Vesna Ocelic Blagojevic
Summary: The aim of this study was to prepare polyacrylate emulsions with modified titanium dioxide nanoparticles. The results showed that the addition of modified fillers led to the formation of particles with a larger hydrodynamic diameter and a significant increase in the viscosity of the emulsion. The morphology indicated poorer dispersibility and distribution of the modified fillers in the polymer, while the thermal stability of the emulsion was significantly increased by the addition of modified TiO2 nanoparticles. The modifications also affected the UV absorption and photocatalytic effect of TiO2.
PROGRESS IN ORGANIC COATINGS
(2023)
Article
Chemistry, Applied
Tugba Tabanligil Calam, Guelsen Taskin Cakici
Summary: In this paper, a modified electrode was used to determine sunset yellow by electrochemical deposition. The optimal experimental conditions were determined and the analytical performance of the sensor was improved using response surface methodology. The proposed sensor showed satisfactory results in determining sunset yellow concentration in instant powder drink and orange-flavored carbonated drink samples.
Article
Nanoscience & Nanotechnology
Sol An, Jieun Nam, Catherine Kanimozhi, Youngjoo Song, Seungjun Kim, Naechul Shin, Padma Gopalan, Myungwoong Kim
Summary: We have reported a method to fabricate photocross-linkable and surface-functionalizable polymeric thin films using reactive cyclic dithiocarbonate (DTC)-containing copolymers. The chemical functionalities of the material surfaces were precisely defined using light illumination. By analyzing the reaction kinetics, the DTC copolymers were cross-linked into a coating using a bifunctional urethane cross-linker. The surface concentrations of unreacted DTC and thiol were effectively controlled by adjusting the amounts of the copolymer and cross-linker. The resulting DTC, thiol, and carboxylic acid groups were successfully transformed into different functionalities via sequential nucleophilic ring opening, thiol-ene, and carbodiimide coupling reactions. This method has the potential to create organic coatings with multiple functional groups under ambient conditions.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Materials Science, Multidisciplinary
Chih-Yu Wu, Yu-Chih Chiang, Jane Christy, Abel Po-Hao Huang, Nai-Yun Chang, Wenny, Yu-Chih Chiu, Yen-Ching Yang, Po-Chun Chen, Peng-Yuan Wang, Hsien-Yeh Chen
Summary: The vapor-phase coating technique based on functionalized poly-p-xylylene provides a surface modification for stem cell culture, enabling the immobilization of growth factors with high specificity and rapid kinetics. This modification system shows biocompatibility, substrate-independent conformity, and stability, offering an effective and versatile interface platform for biomedical applications.
Article
Engineering, Environmental
A. Asadi, S. Nazari, F. Gholami, M. Dolatshah
Summary: The poly-acrylonitrile (PAN) ultrafiltration (UF) membrane showed a significant improvement in permeability and antifouling performance after incorporating dopamine, protease, and lipase. SEM, ATR-FTIR, zeta potential, AFM, and contact angle were used to analyze the surface chemistry, roughness, and hydrophilicity of the modified membrane. The optimized membrane exhibited excellent hydrophilicity, water flux, and removal efficiencies for natural organic matter. Moreover, the enzyme-immobilized membrane showed outstanding antifouling performance, stability, and antibacterial properties against E. coli and S. aureus.
JOURNAL OF WATER PROCESS ENGINEERING
(2023)
Article
Chemistry, Multidisciplinary
Yiling Nie, Shihong Zhang, Yi He, Liyun Zhang, Yuqi Wang, Shuangshuang Li, Na Wang
Summary: This study reports a simple one-step method to modify electrospun PVDF nanofiber membranes, improving their wettability and achieving superhydrophilic/underwater superoleophobic properties. The modified membranes exhibit high flux and excellent separation efficiency in oil-water separation processes. The membranes also show good stability and recyclability after multiple cycles.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Physical
Chang Kyu Rhee, Andrey E. Burov, Alexey P. Puzyr, Vladimir S. Bondar
Summary: The study investigated the applicability of detonation nanodiamonds as a carrier for corticosteroids delivery, demonstrating a sustained release effect of the adsorbed drugs.
APPLIED SURFACE SCIENCE
(2021)
Article
Polymer Science
Halyna Ohar, Maria Tokareva, Oleg Nagursky, Jaroslav Mosnacek, Viktor Tokarev
Summary: A new approach to the synthesis of macrophotoinitiators (MPIs) was developed and their effective application for curing polymer composites after immobilization on the surface of diverse mineral fillers was demonstrated. The MPIs were shown to be effective surface modifiers and photoinitiators for mineral fillers.
JOURNAL OF APPLIED POLYMER SCIENCE
(2022)
Article
Engineering, Biomedical
Zheyu Wang, Jingyi Luan, Anushree Seth, Lin Liu, Minli You, Prashant Gupta, Priya Rathi, Yixuan Wang, Sisi Cao, Qisheng Jiang, Xiao Zhang, Rohit Gupta, Qingjun Zhou, Jeremiah J. Morrissey, Erica L. Scheller, Jai S. Rudra, Srikanth Singamaneni
Summary: Microneedle patches enable rapid sampling and on-needle quantification of target protein biomarkers in interstitial fluid, offering a new possibility for early disease diagnosis.
NATURE BIOMEDICAL ENGINEERING
(2021)
Article
Nanoscience & Nanotechnology
Chao Liang, Jingyi Luan, Zheyu Wang, Qisheng Jiang, Rohit Gupta, Sisi Cao, Keng-Ku Liu, Jeremiah J. Morrissey, Evan D. Kharasch, Rajesh R. Naik, Srikanth Singamaneni
Summary: The size of gold nanorods plays a crucial role in the fluorescence enhancement efficacy, with larger dimensions leading to better enhancement up to a certain point before diminishing returns. Finite-difference time-domain (FDTD) simulations reveal that the electromagnetic field around plasmonic nanostructures is responsible for the size-dependent fluorescence enhancement efficiency of gold nanorods.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Chemistry, Physical
Minli You, Pengpeng Jia, Xiaocong He, Zheyu Wang, Shangsheng Feng, Yulin Ren, Zedong Li, Lei Cao, Bin Gao, Chunyan Yao, Srikanth Singamaneni, Feng Xu
Summary: A simple method has been developed to quantify and adjust the nano-localized temperature field around AuNRs by combining experimental measurement and numerical simulation. The method first developed an indirect way to measure the surface temperature of AuNRs by utilizing the temperature-dependent stability of the Au-thiol bond. Meanwhile, the relationship of AuNRs' surface temperature with the AuNRs concentration and laser intensity is also studied.
Article
Nanoscience & Nanotechnology
Yun Zeng, Peng Chang, Jingwen Ma, Ke Li, Chunhong Zhang, Yingying Guo, Hanrui Li, Qingxia Zhu, Huifang Liu, Wenjing Wang, Yuwei Chen, Dan Chen, Xu Cao, Yonghua Zhan
Summary: In this study, we developed a DNA origami-based theranostic nanoplatform to explain the variation of tumor hypoxia during chemotherapy. Through in vitro and in vivo experiments, we demonstrated that the nanoplatform can release drugs and alleviate tumor hypoxia. Photoacoustic and fluorescence imaging were used to evaluate these effects.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Chemistry, Analytical
Zheyu Wang, Jeremiah J. Morrissey, Lin Liu, Yixuan Wang, Qingjun Zhou, Rajesh R. Naik, Srikanth Singamaneni
Summary: Development of a rapid, ultrasensitive multiplexed epitope-specific serological assay for SARS-CoV-2 antibodies can help in precise diagnosis, prediction of clinical outcomes, and evaluation of immune protection, offering potential for advanced epidemiology studies and better clinical outcomes.
ANALYTICAL CHEMISTRY
(2022)
Article
Biophysics
Zheyu Wang, Qingjun Zhou, Anushree Seth, Samhitha Kolla, Jingyi Luan, Qisheng Jiang, Priya Rathi, Prashant Gupta, Jeremiah J. Morrissey, Rajesh R. Naik, Srikanth Singamaneni
Summary: In this research, a simple, rapid, and ultrasensitive method for detection and quantification of small molecules was developed, which can be used for multiplexed detection of various small molecules.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Biotechnology & Applied Microbiology
Hanrui Li, Xiaoxia Cai, Tong Yi, Yun Zeng, Jingwen Ma, Lei Li, Liaojun Pang, Na Li, Hao Hu, Yonghua Zhan
Summary: This article describes the development of a self-enhanced Mn3O4 nanoplatform for real-time monitoring and treatment of multidrug resistance (MDR) in gastric cancer. The nanoplatform can enhance TI-weighted magnetic resonance imaging (MRI) and specifically target MDR cells. It also exhibits good chemodynamic activity and photothermal conversion effect, which contribute to the treatment of MDR. In addition, in situ photothermal/chemodynamic synergistic therapy shows promising results.
JOURNAL OF NANOBIOTECHNOLOGY
(2022)
Article
Nanoscience & Nanotechnology
Yun Zeng, Tong Yi, Jingwen Ma, Ming Han, Xinyi Xu, Dan Chen, Xueli Chen, Risheng Wang, Yonghua Zhan
Summary: In this study, a polydopamine (PDA)-mediated antibacterial system was synthesized to achieve in vitro and in vivo antimicrobial activities. The surface modification of nanodiamonds (NDs) was precisely controlled using a mathematical model of PDA deposition. The synthesis conditions, including dopamine concentration, reaction time, and kinetic constant k (1), were discussed. Simulation results showed that PDA deposition was positively correlated with various factors and would be terminated if dissolved O-2 levels were inadequate. The controlled thickness of PDA layers regulated the formation of silver nanoparticles (AgNPs), resulting in enhanced Raman peaks and predicted antibacterial activity against E. coli in vitro. An optimized antibacterial hydrogel incorporating NDs-PDA/Ag was prepared and characterized. Antibacterial tests were performed to promote in vivo wound healing, and the results were confirmed by pathological and immunohistochemical-stained tissue sections. This work provides a theoretical foundation for predicting the PDA-assisted surface modification of NDs, leading to a predictable antibacterial effect and promoting in vivo wound healing.
Review
Chemistry, Multidisciplinary
Yun Zeng, Taotao Dou, Lei Ma, Jingwen Ma
Summary: Photoacoustic (PA) imaging is a noninvasive imaging technique that combines optical and ultrasonic imaging modalities to provide high-quality images. This review explores the current state of exogenous PA contrast agents, their merits and limitations, and their future development, categorizing them into always-on and turn-on based on their activation mechanism.
Article
Engineering, Environmental
Yun Zeng, Yonghua Zhan, Xinyue Liu, Jingwen Ma, Huifang Liu, Hanrui Li, Tong Yi, Qingxia Zhu, Getao Du, Linfei Zhao, Dan Chen, Xueli Chen
Summary: This article aims to develop and modify a CuS-based nanoplatform for actively targeting and internalizing drugs into tumor cells. The properties of the nanoplatform, such as shape, spectra, drug encapsulation efficiency, etc., are characterized. The study shows that the nanoplatform has good active-targeted capacity and high-efficiency photothermal therapy effect, which has the potential for cancer treatment and prognosis improvement.
CHEMICAL ENGINEERING JOURNAL
(2022)
Review
Radiology, Nuclear Medicine & Medical Imaging
Getao Du, Yun Zeng, Dan Chen, Wenhua Zhan, Yonghua Zhan
Summary: Gastric cancer is a common malignant tumor with high mortality rates worldwide. Early detection and diagnosis are crucial for improving patient prognosis. Radiomics, which quantifies tumor phenotypes using quantitative image features, has been applied to various aspects of gastric cancer, including histopathological grading, differential diagnosis, therapeutic efficacy, and prognosis evaluation. This review evaluates the research status and progress of radiomics in gastric cancer and discusses its workflow and clinical application. The included studies indicated positive results, highlighting the potential of radiomics in early prediction and diagnosis of gastric cancer. However, challenges in radiomics development were also identified.
JAPANESE JOURNAL OF RADIOLOGY
(2023)
Article
Chemistry, Physical
Yun Zeng, Linfei Zhao, Ke Li, Jingwen Ma, Dan Chen, Changhu Liu, Wenhua Zhan, Yonghua Zhan
Summary: In this study, aptamer-functionalized liposomes were developed to encapsulate the chemotherapeutic drug TMZ and photothermal agent IR780 for the treatment of gliomas. These liposomes can effectively target orthotopic gliomas and reverse TMZ resistance, leading to extended survival time in tumor-bearing mice.
Article
Chemistry, Multidisciplinary
Yun Zeng, Huifang Liu, Jingwen Ma, Ke Li, Peng Chang, Chenying Wang, Lei Li, Dan Chen, Changhu Liu, Na Li, Wenhua Zhan, Yonghua Zhan
Summary: Encasing gossypol in glyceryl monooleate (GMO) and making it coordinate cobalt ferrite can improve its photothermal conversion efficiency and help it enter tumor cells, inducing tumor apoptosis and enhancing chemotherapy.
Article
Biochemical Research Methods
Anushree Seth, Ekansh Mittal, Jingyi Luan, Samhitha Kolla, Monty B. Mazer, Hemant Joshi, Rohit Gupta, Priya Rathi, Zheyu Wang, Jeremiah J. Morrissey, Joel D. Ernst, Cynthia Portal-Celhay, Sharon Celeste Morley, Jennifer A. Philips, Srikanth Singamaneni
Summary: The study introduces a method called FluoroDOT assay, which utilizes ultrabright nanoparticle plasmonic-fluors for high-resolution imaging of protein secretion. This versatile assay allows for exploration of spatial distribution of proteins secreted by single cells, the study of cell-to-cell heterogeneity in secretion, and detection of low abundance or incipient secretion of proteins.
CELL REPORTS METHODS
(2022)
Article
Physiology
Yeawon Kim, Zheyu Wang, Chuang Li, Kendrah Kidd, Yixuan Wang, Bryce G. Johnson, Stanislav Kmoch, Jeremiah J. Morrissey, Anthony J. Bleyer, Jeremy S. Duffield, Srikanth Singamaneni, Ying Maggie Chen
Summary: ADTKD-UMOD is a common genetic kidney disease with clinical heterogeneity, lacking screening tests. The study found that mutant UMOD exclusively upregulates an endoplasmic reticulum chaperone, BiP, in thick ascending limb cells, serving as an early urinary endoplasmic reticulum stress biomarker. The ultrasensitive p-FLISA developed in this study could potentially aid in monitoring disease progression and guiding targeted therapies in ADTKD.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY
(2021)
