Article
Chemistry, Physical
Jotam Bergfreund, Michael Diener, Thomas Geue, Natalie Nussbaum, Nico Kummer, Pascal Bertsch, Gustav Nystrom, Peter Fischer
Summary: The polarity of the oil phase has a significant impact on the formation of globular protein networks at fluid interfaces, including the degree of protein unfolding, protein location, and network strength.
Article
Chemistry, Physical
Camille Faucon, Pascale Chalier, Christian Sanchez
Summary: This article investigates the adsorption of Acacia gum to oil-water interfaces using interfacial tension and rheological analysis. It is found that Acacia gum forms a viscoelastic interfacial structure through a 3-phase mechanism, and the interaction energy between water and oil plays a crucial role in determining the interfacial properties of Acacia gum. A volumetric adsorption mechanism is proposed, and the possible emergence of a gel-like transient dissipative structure is discussed.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Chemistry, Physical
Sashikumar Ramamirtham, Martin A. K. Williams, Davoud Zare, Mike Weeks, Catherine P. Whitby
Summary: Complexation of high-methylesterified pectins with beta-lactoglobulin at pH 4 can strengthen protein films at dodecane/water interfaces, doubling the steady state shear elastic moduli. The charge density and pattern of the polysaccharide primarily determine the lag times of film formation. Adsorbed beta-lactoglobulin molecules cross-link in the aqueous phase, strengthening the resulting interfacial layer.
Article
Chemistry, Physical
Theresia Heiden-Hecht, Baohu Wu, Kuno Schwaerzer, Stephan Forster, Joachim Kohlbrecher, Olaf Holderer, Henrich Frielinghaus
Summary: This study utilized SAXS and SANS techniques to analyze the structure of protein-stabilized emulsions. The results showed that SAXS could detect the changes in protein shape below the critical interfacial concentration (CIC), while SANS determined the interfacial structure both below and above the CIC, as well as oil droplet radius and interfacial coverage.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2024)
Article
Chemistry, Physical
Boris A. Noskov, Anastasiya R. Rafikova, Olga Yu Milyaeva
Summary: The spread and adsorbed layers of beta-lactoglobulin (BLG) microgel were investigated using dilational surface rheology, atomic force microscopy, and optical microscopy. It was found that the BLG microgel exhibited a special collapse mechanism not observed in layers of soft and rigid nano- and microparticles.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Biochemistry & Molecular Biology
Alexandra Chrysanthou, Minerva Bosch-Fortea, Julien E. Gautrot
Summary: Bioemulsions are promising platforms for the enlargement of adherent cells and stem cells. In this study, protein nanosheets based on bovine serum albumin (BSA) and beta-lactoglobulin (BLG) were designed and functionalized with RGDSP peptides to enable cell adhesion. The results demonstrate that BLG nanosheets, even without cosurfactants, have high elasticity and can support the adhesion and proliferation of mesenchymal stem cells and human embryonic kidney (HEK) cells on bioemulsions stabilized by RGD-functionalized protein nanosheets.
Article
Chemistry, Multidisciplinary
Hai Yu, Lanlan Qin, Jian Zhou
Summary: This study used molecular dynamics simulations to investigate the effect of oil polarity on the orientation and conformation of proteins at oil-water interfaces. It was found that the oil polarity can influence the protein adsorption orientation and conformation by modulating intermolecular interactions. Therefore, the stability and activity of proteins can be regulated by changing the oil polarity.
Article
Chemistry, Physical
Nan Yang, Jing Ye, Jing Li, Bing Hu, Robert L. Leheny, Katsuyoshi Nishinari, Yapeng Fang
Summary: Proteins easily self-assemble into different aggregates during processing, such as nanoparticles and fibrils, showing strong interfacial activity at the oil-water interface. By controlling heating temperature and pH, beta-lactoglobulin aggregates were prepared in solution and characterized for their surface properties. The study demonstrated that beta-lg thermal aggregates exhibit excellent emulsification ability and significant impact on fat digestion in food emulsions.
Article
Chemistry, Applied
Maria Luisa Lopez-Castejon, Carlos Bengoechea, Jose Manuel Alguacil, Cecilio Carrera
Summary: Inulin, a prebiotic ingredient used in the food industry, has been found to influence the properties of food foams at lower concentrations, while higher concentrations lead to the control of system behavior by the properties of the continuous phase. Interfacial rheological properties play a key role at lower inulin concentrations, while at higher concentrations, the influence is hindered by the properties of the continuous phase. The results highlight the role of inulin in promoting air/water interface stabilization and its thickening effect.
FOOD HYDROCOLLOIDS
(2021)
Article
Chemistry, Multidisciplinary
Roy J. B. M. Delahaije, Leonard M. C. Sagis, Jack Yang
Summary: Understanding the interface-stabilizing properties of surface-active components is important for designing stable macroscopic multiphase systems. This study evaluated the impact of particle sedimentation on pendant drop tensiometry and found that the presence of sedimenting particles can lead to a decrease in measured surface tension. These findings highlight the need to consider sedimentation effects in pendant drop tensiometry measurements.
Article
Engineering, Environmental
Meruyert Nazhipkyzy, Dana Assylkhanova, Nurgain Araylim, Aigerim Seitkazinova, Gamzenur Ozsin, Esin Apaydin Varol
Summary: In this study, a flexible and porous hydrophilic melamine sponge was coated by superhydrophobic soot for the efficient removal of petroleum oil. The soot-coated sponge exhibited excellent superhydrophobicity and high adsorption capacity, and maintained this capacity even after multiple cycles of use, making it a promising candidate for oil-polluted water treatment.
JOURNAL OF WATER PROCESS ENGINEERING
(2022)
Article
Polymer Science
Christoph S. Hundschell, Juliane Bruehan, Theresa Anzmann, Reinhard Kohlus, Anja M. Wagemans
Summary: This study characterized the influence of levan on the phase behavior and gelation of mixed beta-lactoglobulin-levan gels. The results showed that levan enhanced gel formation and aggregation of beta-1g due to segregative forces between the polymer species. The presence of levan also increased the water binding of the gel networks, although this effect decreased with increasing levan content. At high ionic strength and high levan content, phase separated gels were formed.
Article
Materials Science, Paper & Wood
Huimin Li, Jingyi Huang, Shen Shen, Chaoran Meng, Hongbo Wang, Jiajia Fu
Summary: In this study, hydrophobic modifiers, silica nanoparticles and methyl trimethoxysilane, were used to prepare superhydrophobic sodium alginate/sodium carboxymethyl cellulose (SA/CMC) aerogel, solving the hydrophilicity issue of polysaccharide-based aerogel. The resulting aerogel exhibited a density of 0.080 g/cm(3), porosity of 94%, and excellent adsorption ability for organic solvents. The superhydrophobic aerogel demonstrated water stability, suitable compressive strength, and great potential for applications in oil-water separation and textile dye wastewater treatment.
Article
Energy & Fuels
Lamia Goual, Bingjun Zhang, Youssra Rahham
Summary: This study utilized Transmission Electron Microscopy to provide nanoscale characterization of thin films responsible for oil/water emulsion stability, revealing vertical stacks of wormlike asphaltene clusters that form a protective layer and reduce interfacial tension at the interface.
Article
Chemistry, Multidisciplinary
Hai Yu, Shengjiang Yang, Zheng Chen, Zhiyong Xu, Xuebo Quan, Jian Zhou
Summary: Hydrophobins are widely used in the food, pharmaceutical, and chemical industries as potential protein emulsifiers. This study employed molecular dynamics simulations to investigate the adsorption orientation and conformation change of hydrophobin HFBI at the oil-water interface. The results showed that HFBI adsorbed at the interface with a patch-up orientation towards the oil phase, maintaining its secondary structure intact. The driving force for adsorption was primarily determined by van der Waals interactions, while the adsorption orientation and conformation were regulated by hydrophobic patches and key residues.
Review
Chemistry, Multidisciplinary
Pascal Bertsch, Mani Diba, David J. Mooney, Sander C. G. Leeuwenburgh
Summary: Biomaterials that can self-heal and maintain their structural integrity have significant advantages in biomedicine. Self-healing injectable hydrogels, a new type of biomaterial, have emerged in the past decade. These hydrogels can temporarily fluidize and then recover their mechanical properties under shear stress. They can be administered locally and minimally invasively, and have moldable properties for personalized medicine. Additionally, they facilitate tissue regeneration through their viscoelastic and diffusive nature. However, challenges remain in balancing self-healing and injectability with physical stability, establishing consensus on rheological characterization, and translating them into therapeutically effective formulations for specific tissues.
Article
Surgery
Emily Lenart, Dina Filiberto, Peter Fischer, Isaac Howley, Saskya Byerly
Summary: Isolated facial fractures (IFF) are often overtriaged and can be managed without surgery. However, they are frequently transferred between hospitals, suggesting the potential for outpatient follow-up or telehealth consultation to decrease resource utilization.
AMERICAN JOURNAL OF SURGERY
(2023)
Article
Chemistry, Physical
Kim Mishra, Nico Kummer, Jotam Bergfreund, Fabian Kampf, Pascal Bertsch, Robin Pauer, Gustav Nystrom, Peter Fischer, Erich J. Windhab
Summary: The crystallization behavior of lipids, especially triacylglycerols, has been studied using various microscopy techniques. It has been found that the shear rate during crystallization affects the structure and growth of crystalline particles. The aggregation of crystallites and the formation of clusters are rate limiting steps in the process. The findings of this study have potential implications in adipose tissue regeneration, microbial lipid crystalline network formation, and energy-efficient chocolate production.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Chemistry, Physical
Diego Milian, Nak Heon Choi, Misgina Tilahun Tsehaye, Peter Fischer, Jens Tuebke, Cristina Iojoiu, Denis C. D. Roux, Nadia El Kissi
Summary: This study presents rheometry as an optimization tool to increase discharge performance of a zinc slurry-air redox flow battery. By investigating the incorporation of electrode suspension slurry to metal-air batteries, the optimal concentration of polyacrylic acid (PAA) for the zinc slurry system was determined, leading to improved performance in the battery.
JOURNAL OF POWER SOURCES
(2023)
Article
Multidisciplinary Sciences
Hamed Almohammadi, Sandra Martinek, Ye Yuan, Peter Fischer, Raffaele Mezzenga
Summary: In the process of nucleation and growth, thermodynamics and kinetics play crucial roles in determining the composition, shape, structure and physical properties of heterogeneous colloidal systems. By selectively choosing colloidal systems and controlling phase separation, we can separate the effects of kinetics from thermodynamics and discover new physical phenomena. This approach enables the on-demand fabrication of multicomponent heterogeneous liquid crystals and opens up new research directions in multicomponent structured fluids.
NATURE COMMUNICATIONS
(2023)
Article
Anesthesiology
Stephan Felder, Peter Fischer, Klaus Boehler, Stefan Angermair, Sascha Treskatsch, Wilfried Witte
Summary: For many years, organ transplantation from postmortem donors has been a crucial therapy for patients with irreversible organ failure. However, in Germany, there has been a disparity between the number of organ donations and the number of patients on the waiting list. The management of anesthesia during multiple organ harvesting from postmortem donors is challenging due to various factors, including limited practical expertise, complex physiological changes, and the absence of guidelines. This paper reviews existing literature to determine evidence-based recommendations for anesthesia management in this context.
ANASTHESIOLOGIE INTENSIVMEDIZIN NOTFALLMEDIZIN SCHMERZTHERAPIE
(2023)
Article
Biochemistry & Molecular Biology
Lea Andree, Pascal Bertsch, Rong Wang, Malin Becker, Jeroen Leijten, Peter Fischer, Fang Yang, Sander C. G. Leeuwenburgh
Summary: We developed a versatile hydrogel platform using modular building blocks, allowing for the design of customized hydrogels with specific physical architecture and mechanical properties. By assembling different combinations of gelatin methacryloyl (Gel-MA) and gelatin nanoparticles, we demonstrated the versatility of the platform. The incorporation of particles resulted in softer hydrogels with enhanced stress relaxation, and the stiffness of the hydrogels influenced cell behavior.
Article
Chemistry, Applied
Pascal Bertsch, Lukas Bocker, Ann-Sophie Palm, Jotam Bergfreund, Peter Fischer, Alexander Mathys
Summary: Proteins from microalgae have the potential to replace animal-based proteins in the human diet or as functional ingredients. Understanding the effect of physicochemical conditions on their adsorption behavior and interfacial network formation is crucial.
FOOD HYDROCOLLOIDS
(2023)
Review
Surgery
Lynley Matthews, Emma Kelly, Andrew Fleming, Saskya Byerly, Peter Fischer, Ian Molyneaux, Andrew Kerwin, Isaac Howley
Summary: This review evaluates the research on outcomes based on field triage to a Level 1 trauma center (L1TC) compared to other levels of hospitals and non-trauma centers. The findings show that the survival benefit of L1TC care is largest for patients with the most severe injuries.
JOURNAL OF SURGICAL RESEARCH
(2023)
Article
Materials Science, Multidisciplinary
Tobias Lojewski, Mohamed F. Elhanoty, Loic Le Guyader, Oscar Granaes, Naman Agarwal, Christine Boeglin, Robert Carley, Andrea Castoldi, Christian David, Carsten Deiter, Florian Doering, RobinY Engel, Florian Erdinger, Hans Fangohr, Carlo Fiorini, Peter Fischer, Natalia Gerasimova, Rafael Gort, Frank deGroot, Karsten Hansen, Steffen Hauf, David Hickin, Manuel Izquierdo, Benjamin E. Van Kuiken, Yaroslav Kvashnin, Charles-Henri Lambert, David Lomidze, Stefano Maffessanti, Laurent Mercadier, Giuseppe Mercurio, Piter S. Miedema, Katharina Ollefs, Matthias Pace, Matteo Porro, Javad Rezvani, Benedikt Roesner, Nico Rothenbach, Andrey Samartsev, Andreas Scherz, Justina Schlappa, Christian Stamm, Martin Teichmann, Patrik Thunstrom, Monica Turcato, Alexander Yaroslavtsev, Jun Zhu, Martin Beye, Heiko Wende, Uwe Bovensiepen, Olle Eriksson, Andrea Eschenlohr
Summary: By combining femtosecond time-resolved X-ray absorption spectroscopy with ab initio time-dependent density functional theory, we analyze the electronic structure of fcc Ni on a femtosecond time scale. We observe transient broadening and energy shifts in the absorption spectra, which are explained by electron repopulation and correlation-induced modifications of the electronic structure, accounting for the local Coulomb interaction.
MATERIALS RESEARCH LETTERS
(2023)
Article
Chemistry, Physical
Nico Kummer, Caroline E. Giacomin, Peter Fischer, Silvia Campioni, Gustav Nystrom
Summary: Amyloid fibrils from inexpensive food proteins and nanocellulose have diverse applications and their hybrid materials have improved mechanical properties due to electrostatic interactions. These interactions increase the elasticity of the amyloid network by cross-linking individual fibrils. The combination of nanocellulose morphology contributes differently to the elasticity, with cellulose nanocrystals inducing bundling and network formation, and cellulose nanofibrils forming a second network. The gained knowledge on colloidal interactions provides a basis for designing functional biohybrid materials.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Materials Science, Ceramics
L. A. B. Cuypers, P. Bertsch, R. Wang, H. R. Harhangi, L. S. Joziasse, X. F. Walboomers, L. van Niftrik, F. Yang, S. C. G. Leeuwenburgh
Summary: In the face of antibiotic resistance, the delivery of therapeutic metal ions through osteogenic nanoparticles provides a viable alternative for treating bone infections. A study found that zinc ions exhibited antibacterial effects at non-toxic levels, and zinc-doped hydroxyapatite nanoparticles with 15 mol% zinc content showed the optimal balance between cytocompatibility and antibacterial efficacy. These nanoparticles show promise as deliverable biomaterials for bone infection treatment.
