Inflammatory mediators reduce surface PrPc on human BMVEC resulting in decreased barrier integrity

The Role of Shed PrPcin the Neuropathogenesis of HIV Infection

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The Biological Function of the Prion Protein: A Cell Surface Scaffold of Signaling Modules

(2017) Rafael Linden   Frontiers in Molecular Neuroscience

Vascular endothelial growth factor: a neurovascular target in neurological diseases

(2016) Christian Lange et al.   Nature Reviews Neurology

HIV-associated neurocognitive disorder — pathogenesis and prospects for treatment

(2016) Deanna Saylor et al.   Nature Reviews Neurology

The nucleo-junctional interplay of the cellular prion protein: A new partner in cancer-related signaling pathways?

(2016) Monique Rousset et al.   Prion

Cognitive Impairment and Persistent CNS Injury in Treated HIV

(2016) Phillip Chan et al.   Current HIV/AIDS Reports

The prion protein inhibits monocytic cell migration by stimulating  1 integrin adhesion and uropod formation

(2015) D. D. Richardson et al.   JOURNAL OF CELL SCIENCE

PrPC signalling in neurons: From basics to clinical challenges

(2014) Théo Z. Hirsch et al.   BIOCHIMIE

Role of Lipid Rafts and GM1 in the Segregation and Processing of Prion Protein

(2014) Laura Botto et al.   PLoS One

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HIV-1-Related Central Nervous System Disease: Current Issues in Pathogenesis, Diagnosis, and Treatment

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The Soluble Form of the Cellular Prion Protein Enhances Phagocytic Activity and Cytokine Production by Human Monocytes Via Activation of ERK and NF-κB

(2013) Jae-Won Jeon et al.   Immune Network

Requirement of Cellular Prion Protein for Intestinal Barrier Function and Mislocalization in Patients With Inflammatory Bowel Disease

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Monocyte maturation, HIV susceptibility, and transmigration across the blood brain barrier are critical in HIV neuropathogenesis

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Tumor Necrosis Factor-alpha and the Roles it Plays in Homeostatic and Degenerative Processes Within the Central Nervous System

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Human Immunodeficiency Virus Infection of Human Astrocytes Disrupts Blood-Brain Barrier Integrity by a Gap Junction-Dependent Mechanism

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PrPC, the Cellular Isoform of the Human Prion Protein, Is a Novel Biomarker of HIV-Associated Neurocognitive Impairment and Mediates Neuroinflammation

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TNF-  Signals Through PKC /NF- B to Alter the Tight Junction Complex and Increase Retinal Endothelial Cell Permeability

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The role of lipid rafts in prion protein biology

(2010) Victoria Lewis   Frontiers in Bioscience-Landmark

Tumour necrosis factor-α affects blood-brain barrier permeability and tight junction-associated occludin in acute liver failure

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HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER Study

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PPARα and PPARγ attenuate HIV-induced dysregulation of tight junction proteins by modulations of matrix metalloproteinase and proteasome activities

(2009) Wen Huang et al.   FASEB JOURNAL

Caveolae-mediated Internalization of Occludin and Claudin-5 during CCL2-induced Tight Junction Remodeling in Brain Endothelial Cells

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Characterization of prion protein-enriched domains, isolated from rat cerebellar granule cells in culture

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VEGF-mediated disruption of endothelial CLN-5 promotes blood-brain barrier breakdown

(2009) Azeb Tadesse Argaw et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blood-brain barrier tight junction permeability and ischemic stroke

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The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders

(2008) Berislav V. Zlokovic   NEURON