Interleukin-6 determines protein stabilization of DNA methyltransferases and alters DNA promoter methylation of genes associated with insulin signaling and angiogenesis

Endothelial fibrosis induced by suppressed STAT3 expression mediated by signaling involving the TGF-β1/ALK5/Smad pathway

(2017) Alvaro Becerra et al.   LABORATORY INVESTIGATION

Biological implications and therapeutic significance of DNA methylation regulated genes in cervical cancer

(2016) Samatha Bhat et al.   BIOCHIMIE

Epigenetic Changes in Diabetes and Cardiovascular Risk

(2016) Samuel T. Keating et al.   CIRCULATION RESEARCH

Aberrant DNA methylation in the pathogenesis of atherosclerosis

(2016) Zhang Hai et al.   CLINICA CHIMICA ACTA

Transcriptional repression of SOCS3 mediated by IL-6/STAT3 signaling via DNMT1 promotes pancreatic cancer growth and metastasis

(2016) Li Huang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Dynamic DNA methylation of matrix metalloproteinase-9 in the development of diabetic retinopathy

(2016) Renu A Kowluru et al.   LABORATORY INVESTIGATION

Knockdown of DNMT1 and DNMT3a Promotes the Angiogenesis of Human Mesenchymal Stem Cells Leading to Arterial Specific Differentiation

(2016) Rui Zhang et al.   STEM CELLS

Alternation of histone and DNA methylation in human atherosclerotic carotid plaques

(2015) Rudolf Napieralski et al.   THROMBOSIS AND HAEMOSTASIS

DNA methylation as a diagnostic and therapeutic target in the battle against Type 2 diabetes

(2015) Tina Rönn et al.   Epigenomics

Epigenetic mechanisms of endothelial dysfunction in type 2 diabetes

(2015) Francesco Prattichizzo et al.   Clinical Epigenetics

Global DNA methylation analysis of human atherosclerotic plaques reveals extensive genomic hypomethylation and reactivation at imprinted locus 14q32 involving induction of a miRNA cluster

(2014) E. Aavik et al.   EUROPEAN HEART JOURNAL

Hydrogen Sulfide Epigenetically Attenuates Homocysteine-Induced Mitochondrial Toxicity Mediated Through NMDA Receptor in Mouse Brain Endothelial (bEnd3) Cells

(2014) Pradip K. Kamat et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Flow-dependent epigenetic DNA methylation regulates endothelial gene expression and atherosclerosis

(2014) Jessilyn Dunn et al.   JOURNAL OF CLINICAL INVESTIGATION

Insulin Resistance Induced by Hyperinsulinemia Coincides with a Persistent Alteration at the Insulin Receptor Tyrosine Kinase Domain

(2014) Karyn J. Catalano et al.   PLoS One

Genome-Wide DNA Methylation Analysis of Human Pancreatic Islets from Type 2 Diabetic and Non-Diabetic Donors Identifies Candidate Genes That Influence Insulin Secretion

(2014) Tasnim Dayeh et al.   PLoS Genetics

Circulating Inflammatory Markers and the Risk of Vascular Complications and Mortality in People With Type 2 Diabetes and Cardiovascular Disease or Risk Factors: The ADVANCE Study

(2013) G. Lowe et al.   DIABETES

Role of DNA methyltransferase 1 on the altered eNOS expression in human umbilical endothelium from intrauterine growth restricted fetuses

(2013) Bernardo J Krause et al.   Epigenetics

Dynamic DNA methylation across diverse human cell lines and tissues

(2013) K. E. Varley et al.   GENOME RESEARCH

T-cadherin attenuates insulin-dependent signalling, eNOS activation, and angiogenesis in vascular endothelial cells

(2012) Maria Philippova et al.   CARDIOVASCULAR RESEARCH

Global DNA Methylation Is Associated With Insulin Resistance: A Monozygotic Twin Study

(2011) J. Zhao et al.   DIABETES

Genome-wide analysis distinguishes hyperglycemia regulated epigenetic signatures of primary vascular cells

(2011) L. Pirola et al.   GENOME RESEARCH

Insulin promoter DNA methylation correlates negatively with insulin gene expression and positively with HbA1c levels in human pancreatic islets

(2010) B. T. Yang et al.   DIABETOLOGIA

Upregulation of DNA Methyltransferase-Mediated Gene Silencing, Anchorage-Independent Growth, and Migration of Colon Cancer Cells by Interleukin-6

(2010) E. Foran et al.   MOLECULAR CANCER RESEARCH

Interleukin-6 Attenuates Insulin-Mediated Increases in Endothelial Cell Signaling but Augments Skeletal Muscle Insulin Action via Differential Effects on Tumor Necrosis Factor-  Expression

(2009) D. Y.C. Yuen et al.   DIABETES

Circos: An information aesthetic for comparative genomics

(2009) M. Krzywinski et al.   GENOME RESEARCH

Insulin Gene Expression Is Regulated by DNA Methylation

(2009) Akio Kuroda et al.   PLoS One

A requirement for thioredoxin in redox-sensitive modulation of T-cadherin expression in endothelial cells

(2008) Manjunath B. Joshi et al.   BIOCHEMICAL JOURNAL

Mechanism of thrombin mediated eNOS phosphorylation in endothelial cells is dependent on ATP levels after stimulation

(2008) Brynhildur Thors et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Overexpression of Il6 leads to hyperinsulinaemia, liver inflammation and reduced body weight in mice

(2008) S. Franckhauser et al.   DIABETOLOGIA

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH