The NDPK/NME superfamily: state of the art

Metastasis suppressor NM23 limits oxidative stress in mammals by preventing activation of stress-activated protein kinases/JNKs through its nucleoside diphosphate kinase activity

(2017) Evelyne Peuchant et al.   FASEB JOURNAL

NME4/nucleoside diphosphate kinase D in cardiolipin signaling and mitophagy

(2017) Uwe Schlattner et al.   LABORATORY INVESTIGATION

Oncogenic Epstein–Barr virus recruits Nm23-H1 to regulate chromatin modifiers

(2017) Saurabh Pandey et al.   LABORATORY INVESTIGATION

Metastasis suppressors: functional pathways

(2017) Imran Khan et al.   LABORATORY INVESTIGATION

NM23/NDPK proteins in transcription regulatory functions and chromatin modulation: emerging trends

(2017) Shalu Sharma et al.   LABORATORY INVESTIGATION

Nm23-H1-stabilized hnRNPA2/B1 promotes internal ribosomal entry site (IRES)-mediated translation of Sp1 in the lung cancer progression

(2017) Chia-Yang Hung et al.   Scientific Reports

Cellular and Molecular Mechanisms of MT1-MMP-Dependent Cancer Cell Invasion

(2016) Antonio Castro-Castro et al.   Annual Review of Cell and Developmental Biology

EMT, cell plasticity and metastasis

(2016) Christine L. Chaffer et al.   CANCER AND METASTASIS REVIEWS

NDPK-D (NM23-H4)-mediated externalization of cardiolipin enables elimination of depolarized mitochondria by mitophagy

(2016) V E Kagan et al.   CELL DEATH AND DIFFERENTIATION

Membrane fission by dynamin: what we know and what we need to know

(2016) Bruno Antonny et al.   EMBO JOURNAL

Identification of PGAM5 as a Mammalian Protein Histidine Phosphatase that Plays a Central Role to Negatively Regulate CD4 + T Cells

(2016) Saswati Panda et al.   MOLECULAR CELL

Metastasis suppressors Nm23H1 and Nm23H2 differentially regulate neoplastic transformation and tumorigenesis

(2015) Yao Tong et al.   CANCER LETTERS

Monoclonal 1- and 3-Phosphohistidine Antibodies: New Tools to Study Histidine Phosphorylation

(2015) Stephen Rush Fuhs et al.   CELL

The Ubiquitin E3 Ligase SCF-FBXO24 Recognizes Deacetylated Nucleoside Diphosphate Kinase A To Enhance Its Degradation

(2015) Wei Chen et al.   MOLECULAR AND CELLULAR BIOLOGY

Progress on Nme (NDP kinase/Nm23/Awd) gene family-related functions derived from animal model systems: studies on development, cardiovascular disease, and cancer metastasis exemplified

(2015) Tien Hsu et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

p63/MT1-MMP axis is required for in situ to invasive transition in basal-like breast cancer

(2015) C Lodillinsky et al.   ONCOGENE

NME2 Reduces Proliferation, Migration and Invasion of Gastric Cancer Cells to Limit Metastasis

(2015) Yan-fei Liu et al.   PLoS One

Notch signaling during development requires the function of awd, the Drosophila homolog of human metastasis suppressor gene Nm23

(2014) Marilena Ignesti et al.   BMC BIOLOGY

A phase II study of medroxyprogesterone acetate in patients with hormone receptor negative metastatic breast cancer: translational breast cancer research consortium trial 007

(2014) Kathy D. Miller et al.   BREAST CANCER RESEARCH AND TREATMENT

Nucleoside diphosphate kinases (NDPKs) in animal development

(2014) Krisztina Takács-Vellai et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

An EMMPRIN- -catenin-Nm23 complex drives ATP production and actomyosin contractility at endothelial junctions

(2014) V. Moreno et al.   JOURNAL OF CELL SCIENCE

A therapeutic approach to treat prostate cancer by targeting Nm23-H1/h-Prune interaction

(2014) Marianeve Carotenuto et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Inhibition of telomerase activity by NME2: impact on metastasis suppression?

(2014) Anirban Kar et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Regulatory functions of Nm23-H2 in tumorigenesis: insights from biochemical to clinical perspectives

(2014) Yuanjun Li et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Non-metastatic 2 (NME2)-mediated suppression of lung cancer metastasis involves transcriptional regulation of key cell adhesion factor vinculin

(2014) Ram Krishna Thakur et al.   NUCLEIC ACIDS RESEARCH

NDK-1, the Homolog of NM23-H1/H2 Regulates Cell Migration and Apoptotic Engulfment in C. elegans

(2014) Luca Fancsalszky et al.   PLoS One

Nucleoside diphosphate kinases fuel dynamin superfamily proteins with GTP for membrane remodeling

(2014) M. Boissan et al.   SCIENCE

Mechanics of Dynamin-Mediated Membrane Fission

(2013) Sandrine Morlot et al.   Annual Review of Biophysics

Nm23-H1 Binds to Gelsolin and Inactivates Its Actin-Severing Capacity to Promote Tumor Cell Motility and Metastasis

(2013) N. Marino et al.   CANCER RESEARCH

c-Abl and Arg induce cathepsin-mediated lysosomal degradation of the NM23-H1 metastasis suppressor in invasive cancer

(2013) L S Fiore et al.   ONCOGENE

Insights into the biology and prevention of tumor metastasis provided by the Nm23 metastasis suppressor gene

(2012) Natascia Marino et al.   CANCER AND METASTASIS REVIEWS

NM23 deficiency promotes metastasis in a UV radiation-induced mouse model of human melanoma

(2012) Stuart G. Jarrett et al.   CLINICAL & EXPERIMENTAL METASTASIS

Dual Function of Mitochondrial Nm23-H4 Protein in Phosphotransfer and Intermembrane Lipid Transfer

(2012) Uwe Schlattner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metastasis Suppressor NM23-H1 Promotes Repair of UV-Induced DNA Damage and Suppresses UV-Induced Melanomagenesis

(2011) S. G. Jarrett et al.   CANCER RESEARCH

Tumor Metastasis: Molecular Insights and Evolving Paradigms

(2011) Scott Valastyan et al.   CELL

Metastasis-suppressor genes in clinical practice: lost in translation?

(2011) Alexander N. Shoushtari et al.   Nature Reviews Clinical Oncology

Nucleoside diphosphate kinase B is required for the formation of heterotrimeric G protein containing caveolae

(2011) Hans-Jörg Hippe et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Learning about the functions of NME/NM23: lessons from knockout mice to silencing strategies

(2011) Mathieu Boissan et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

The Anti-Metastatic nm23-1 Gene Is Needed for the Final Step of Mammary Duct Maturation of the Mouse Nipple

(2011) Camille Deplagne et al.   PLoS One

The suppressor of metastasis Nm23-H1 interacts with the Cdc42 Rho family member and the pleckstrin homology domain of oncoprotein Dbl-1 to suppress cell migration

(2010) Masanao Murakami et al.   CANCER BIOLOGY & THERAPY

Characterization of a Novel Mechanism of Genomic Instability Involving the SEI1/SET/NM23H1 Pathway in Esophageal Cancers

(2010) Y. Li et al.   CANCER RESEARCH

Implication of Metastasis Suppressor NM23-H1 in Maintaining Adherens Junctions and Limiting the Invasive Potential of Human Cancer Cells

(2010) M. Boissan et al.   CANCER RESEARCH

Through scaffolding and catalytic actions nucleoside diphosphate kinase B differentially regulates basal and β-adrenoceptor-stimulated cAMP synthesis

(2010) Hans-Joerg Hippe et al.   CELLULAR SIGNALLING

Nucleoside Diphosphate Kinase B Knock-out Mice Have Impaired Activation of the K+Channel KCa3.1, Resulting in Defective T Cell Activation

(2010) Lie Di et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plakoglobin interacts with and increases the protein levels of metastasis suppressor Nm23-H2 and regulates the expression of Nm23-H1

(2010) Z Aktary et al.   ONCOGENE

Situs Inversus in Dpcd/Poll–/–, Nme7–/–, and Pkd1l1–/– Mice

(2010) P. Vogel et al.   VETERINARY PATHOLOGY

Nme protein family evolutionary history, a vertebrate perspective

(2009) Thomas Desvignes et al.   BMC EVOLUTIONARY BIOLOGY

Coordinated Actions of Actin and BAR Proteins Upstream of Dynamin at Endocytic Clathrin-Coated Pits

(2009) Shawn Ferguson et al.   DEVELOPMENTAL CELL

Targeted deletion ofNm23/nucleoside diphosphate kinase AandBreveals their requirement for definitive erythropoiesis in the mouse embryo

(2009) Edith H. Postel et al.   DEVELOPMENTAL DYNAMICS

The mammalian Nm23/NDPK family: from metastasis control to cilia movement

(2009) Mathieu Boissan et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Double knockout Nme1/Nme2 mouse model suggests a critical role for NDP kinases in erythroid development

(2009) Edith Horn Postel et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

The Drosophila Metastasis Suppressor Gene Nm23 Homolog, awd, Regulates Epithelial Integrity during Oogenesis

(2009) J. A. Woolworth et al.   MOLECULAR AND CELLULAR BIOLOGY

The Class II Phosphatidylinositol 3 kinase C2β Is Required for the Activation of the K+ Channel KCa3.1 and CD4 T-Cells

(2009) Shekhar Srivastava et al.   MOLECULAR BIOLOGY OF THE CELL

The interaction of nucleoside diphosphate kinase B with G   dimers controls heterotrimeric G protein function

(2009) H.-J. Hippe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alteration in gene expression profile and biological behavior in human lung cancer cell line NL9980 by nm23-H1 gene silencing

(2008) Wei Ma et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Heterogeneity of Drug Target Expression Among Metastatic Lesions: Lessons from a Breast Cancer Autopsy Program

(2008) P. S. Steeg   CLINICAL CANCER RESEARCH

Nm23-H1 modulates the activity of the guanine exchange factor Dbl-1

(2008) Masanao Murakami et al.   INTERNATIONAL JOURNAL OF CANCER

EBNA3C Can Modulate the Activities of the Transcription Factor Necdin in Association with Metastasis Suppressor Protein Nm23-H1

(2008) R. Kaul et al.   JOURNAL OF VIROLOGY

awd, the Homolog of Metastasis Suppressor Gene Nm23, Regulates Drosophila Epithelial Cell Invasion

(2008) G. Nallamothu et al.   MOLECULAR AND CELLULAR BIOLOGY

Characterisation of tumoral markers correlated with ErbB2 (HER2/Neu) overexpression and metastasis in breast cancer

(2008) Ma Carmen Durán et al.   Proteomics Clinical Applications