Progress on Nme (NDP kinase/Nm23/Awd) gene family-related functions derived from animal model systems: studies on development, cardiovascular disease, and cancer metastasis exemplified

Nucleoside Diphosphate Kinase B Regulates Angiogenesis Through Modulation of Vascular Endothelial Growth Factor Receptor Type 2 and Endothelial Adherens Junction Proteins

(2014) Yuxi Feng et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Notch signaling during development requires the function of awd, the Drosophila homolog of human metastasis suppressor gene Nm23

(2014) Marilena Ignesti et al.   BMC BIOLOGY

A phase II study of medroxyprogesterone acetate in patients with hormone receptor negative metastatic breast cancer: translational breast cancer research consortium trial 007

(2014) Kathy D. Miller et al.   BREAST CANCER RESEARCH AND TREATMENT

A Splicing Variant of NME1 Negatively Regulates NF-κB Signaling and Inhibits Cancer Metastasis by Interacting with IKKβ

(2014) Dong-Joo You et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of the epithelial Ca2+ channel TRPV5 by reversible histidine phosphorylation mediated by NDPK-B and PHPT1

(2014) Xinjiang Cai et al.   MOLECULAR BIOLOGY OF THE CELL

NDK-1, the Homolog of NM23-H1/H2 Regulates Cell Migration and Apoptotic Engulfment in C. elegans

(2014) Luca Fancsalszky et al.   PLoS One

Nucleoside diphosphate kinases fuel dynamin superfamily proteins with GTP for membrane remodeling

(2014) M. Boissan et al.   SCIENCE

The NM23-H1/H2 homolog NDK-1 is required for full activation of Ras signaling in C. elegans

(2013) N. Masoudi et al.   DEVELOPMENT

Inhibitory effect of upregulated DR-nm23 expression on invasion and metastasis in colorectal cancer

(2013) Lijuan Qu et al.   EUROPEAN JOURNAL OF CANCER PREVENTION

c-Abl and Arg induce cathepsin-mediated lysosomal degradation of the NM23-H1 metastasis suppressor in invasive cancer

(2013) L S Fiore et al.   ONCOGENE

Insights into the biology and prevention of tumor metastasis provided by the Nm23 metastasis suppressor gene

(2012) Natascia Marino et al.   CANCER AND METASTASIS REVIEWS

NM23 deficiency promotes metastasis in a UV radiation-induced mouse model of human melanoma

(2012) Stuart G. Jarrett et al.   CLINICAL & EXPERIMENTAL METASTASIS

nm23-H1 is a negative regulator of TGF-β1-dependent induction of epithelial–mesenchymal transition

(2012) Rongzhi Zhao et al.   EXPERIMENTAL CELL RESEARCH

Dual Function of Mitochondrial Nm23-H4 Protein in Phosphotransfer and Intermembrane Lipid Transfer

(2012) Uwe Schlattner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nm23-H1 regulates contact inhibition of locomotion, which is affected by ephrin-B1

(2012) M. Tanaka et al.   JOURNAL OF CELL SCIENCE

Perspective: The right trials

(2012) Patricia S. Steeg   NATURE

nm23-H1 gene driven by hTERT promoter induces inhibition of invasive phenotype and metastasis of lung cancer xenograft in mice

(2012) Yu Fan et al.   Thoracic Cancer

Metastasis Suppressor NM23-H1 Promotes Repair of UV-Induced DNA Damage and Suppresses UV-Induced Melanomagenesis

(2011) S. G. Jarrett et al.   CANCER RESEARCH

Cell-Permeable NM23 Blocks the Maintenance and Progression of Established Pulmonary Metastasis

(2011) J. Lim et al.   CANCER RESEARCH

Regulation of Nm23-H1 and Cell Invasiveness by Kaposi's Sarcoma-Associated Herpesvirus

(2011) Z. Qin et al.   JOURNAL OF VIROLOGY

AMPK directly inhibits NDPK through a phosphoserine switch to maintain cellular homeostasis

(2011) Rob U. Onyenwoke et al.   MOLECULAR BIOLOGY OF THE CELL

Nucleoside diphosphate kinase B is required for the formation of heterotrimeric G protein containing caveolae

(2011) Hans-Jörg Hippe et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

The Anti-Metastatic nm23-1 Gene Is Needed for the Final Step of Mammary Duct Maturation of the Mouse Nipple

(2011) Camille Deplagne et al.   PLoS One

Implication of Metastasis Suppressor NM23-H1 in Maintaining Adherens Junctions and Limiting the Invasive Potential of Human Cancer Cells

(2010) M. Boissan et al.   CANCER RESEARCH

Through scaffolding and catalytic actions nucleoside diphosphate kinase B differentially regulates basal and β-adrenoceptor-stimulated cAMP synthesis

(2010) Hans-Joerg Hippe et al.   CELLULAR SIGNALLING

Metastasis suppressor function of NM23-H1 requires its 3′-5′ exonuclease activity

(2010) Qingbei Zhang et al.   INTERNATIONAL JOURNAL OF CANCER

Nucleoside Diphosphate Kinase B Knock-out Mice Have Impaired Activation of the K+Channel KCa3.1, Resulting in Defective T Cell Activation

(2010) Lie Di et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nucleoside diphosphate kinase Nm23-H1 regulates chromosomal stability by activating the GTPase dynamin during cytokinesis

(2010) A. R. Conery et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeted deletion ofNm23/nucleoside diphosphate kinase AandBreveals their requirement for definitive erythropoiesis in the mouse embryo

(2009) Edith H. Postel et al.   DEVELOPMENTAL DYNAMICS

Developmental function of Nm23/awd: a mediator of endocytosis

(2009) Gouthami Nallamothu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

The Nm23-H1–h-Prune complex in cellular physiology: a ‘tip of the iceberg’ protein network perspective

(2009) Alessia Galasso et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

The Drosophila Metastasis Suppressor Gene Nm23 Homolog, awd, Regulates Epithelial Integrity during Oogenesis

(2009) J. A. Woolworth et al.   MOLECULAR AND CELLULAR BIOLOGY

The interaction of nucleoside diphosphate kinase B with G   dimers controls heterotrimeric G protein function

(2009) H.-J. Hippe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biogenesis of Caveolae: Stepwise Assembly of Large Caveolin and Cavin Complexes

(2009) Arnold Hayer et al.   TRAFFIC

Alteration in gene expression profile and biological behavior in human lung cancer cell line NL9980 by nm23-H1 gene silencing

(2008) Wei Ma et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Role of protein histidine phosphatase for viability of neuronal cells

(2008) Susanne Klumpp et al.   BRAIN RESEARCH

Nanoparticle delivery of anti-metastatic NM23-H1 gene improves chemotherapy in a mouse tumor model

(2008) Z Li et al.   CANCER GENE THERAPY

awd, the Homolog of Metastasis Suppressor Gene Nm23, Regulates Drosophila Epithelial Cell Invasion

(2008) G. Nallamothu et al.   MOLECULAR AND CELLULAR BIOLOGY

YNK1, the yeast homolog of human metastasis suppressor NM23, is required for repair of UV radiation- and etoposide-induced DNA damage

(2008) Mengmeng Yang et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS