Principles and approaches for reproducible scoring of tissue stains in research

Lack of cystic fibrosis transmembrane conductance regulator disrupts fetal airway development in pigs

(2018) David K. Meyerholz et al.   LABORATORY INVESTIGATION

Use of Severity Grades to Characterize Histopathologic Changes

(2018) Kenneth A. Schafer et al.   TOXICOLOGIC PATHOLOGY

CD8 T cells contribute to lacrimal gland pathology in the nonobese diabetic mouse model of Sjögren syndrome

(2017) Jennifer Y Barr et al.   IMMUNOLOGY AND CELL BIOLOGY

Integrated tumor identification and automated scoring minimizes pathologist involvement and provides new insights to key biomarkers in breast cancer

(2017) Peter Bankhead et al.   LABORATORY INVESTIGATION

Approaches to Evaluate Lung Inflammation in Translational Research

(2017) David K. Meyerholz et al.   VETERINARY PATHOLOGY

Practical Stereology Applications for the Pathologist

(2017) Danielle L. Brown   VETERINARY PATHOLOGY

Quantitative comparison and reproducibility of pathologist scoring and digital image analysis of estrogen receptor β2 immunohistochemistry in prostate cancer

(2016) Anthony E. Rizzardi et al.   Diagnostic Pathology

External quality assessment for immunohistochemistry: experiences from NordiQC

(2015) S Nielsen   BIOTECHNIC & HISTOCHEMISTRY

Glycaemic regulation and insulin secretion are abnormal in cystic fibrosis pigs despite sparing of islet cell mass

(2015) Aliye Uc et al.   CLINICAL SCIENCE

Factors affecting immunoreactivity in long-term storage of formalin-fixed paraffin-embedded tissue sections

(2015) Federica Grillo et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Getting controls under control: the time is now for immunohistochemistry

(2015) Emina Emilia Torlakovic et al.   JOURNAL OF CLINICAL PATHOLOGY

Recommendations for minimum information for publication of experimental pathology data: MINPEPA guidelines

(2015) Cheryl L Scudamore et al.   JOURNAL OF PATHOLOGY

Application of multispectral imaging in quantitative immunohistochemistry study of breast cancer: a comparative study

(2015) Wen-Lou Liu et al.   TUMOR BIOLOGY

Cause-of-Death Analysis in Rodent Aging Studies

(2015) J. M. Snyder et al.   VETERINARY PATHOLOGY

Huntingtin Is Required for Epithelial Polarity through RAB11A-Mediated Apical Trafficking of PAR3-aPKC

(2015) Salah Elias et al.   PLOS BIOLOGY

RSV Vaccine-Enhanced Disease Is Orchestrated by the Combined Actions of Distinct CD4 T Cell Subsets

(2015) Cory J. Knudson et al.   PLoS Pathogens

Canadian Association of Pathologists–Association canadienne des pathologistes National Standards Committee for High Complexity Testing/Immunohistochemistry

(2014) Carol C. Cheung et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Quantitative Analysis of Histological Staining and Fluorescence Using ImageJ

(2014) Ellen C. Jensen   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Standardization of Diagnostic Immunohistochemistry: Literature Review and Geisinger Experience

(2014) Fan Lin et al.   ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE

Different approaches for interpretation and reporting of immunohistochemistry analysis results in the bone tissue – a review

(2014) Nickolay Fedchenko et al.   Diagnostic Pathology

Integrating pathology into human disease modelling - how to eat the elephant

(2014) C. L. Scudamore   Disease Models & Mechanisms

Histopathology reveals correlative and unique phenotypes in a high-throughput mouse phenotyping screen

(2014) H. A. Adissu et al.   Disease Models & Mechanisms

The Use of Mouse Models of Breast Cancer and Quantitative Image Analysis to Evaluate Hormone Receptor Antigenicity after Microwave-assisted Formalin Fixation

(2014) Jesse A. Engelberg et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Controls for Immunohistochemistry

(2014) Stephen M. Hewitt et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Quantitative measurement of cancer tissue biomarkers in the lab and in the clinic

(2014) Daniel E Carvajal-Hausdorf et al.   LABORATORY INVESTIGATION

Digital pathology and image analysis in tissue biomarker research

(2014) Peter W. Hamilton et al.   METHODS

Calculation of the Ki67 index in pancreatic neuroendocrine tumors: a comparative analysis of four counting methodologies

(2014) Michelle D Reid et al.   MODERN PATHOLOGY

Editorial: Antibody Can Get It Right: Confronting Problems of Antibody Specificity and Irreproducibility

(2014) Agnes Schonbrunn   MOLECULAR ENDOCRINOLOGY

The Potential Role of Increasing the Release of Mouse β- Defensin-14 in the Treatment of Osteomyelitis in Mice: A Primary Study

(2014) Chen Zhu et al.   PLoS One

IHC Profiler: An Open Source Plugin for the Quantitative Evaluation and Automated Scoring of Immunohistochemistry Images of Human Tissue Samples

(2014) Frency Varghese et al.   PLoS One

Epithelial Cell Shedding and Barrier Function

(2014) J. M. Williams et al.   VETERINARY PATHOLOGY

Air Trapping and Airflow Obstruction in Newborn Cystic Fibrosis Piglets

(2013) Ryan J. Adam et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Multiparametric and semiquantitative scoring systems for the evaluation of mouse model histopathology - a systematic review

(2013) Robert Klopfleisch   BMC Veterinary Research

Quantitation of fixative-induced morphologic and antigenic variation in mouse and human breast cancers

(2013) Robert D Cardiff et al.   LABORATORY INVESTIGATION

Immunohistochemical Evaluation of the Effects of Paraffin Section Storage on Biomarker Stability

(2013) J. A. Ramos-Vara et al.   VETERINARY PATHOLOGY

Principles for Valid Histopathologic Scoring in Research

(2013) K. N. Gibson-Corley et al.   VETERINARY PATHOLOGY

Interobserver Agreement Among Pathologists for Semiquantitative Hormone Receptor Scoring in Breast Carcinoma

(2012) David A. Cohen et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Quantitative comparison of immunohistochemical staining measured by digital image analysis versus pathologist visual scoring

(2012) Anthony E Rizzardi et al.   Diagnostic Pathology

Utility of multispectral imaging in automated quantitative scoring of immunohistochemistry

(2012) Christopher Fiore et al.   JOURNAL OF CLINICAL PATHOLOGY

An Image Analysis Method for the Precise Selection and Quantitation of Fluorescently Labeled Cellular Constituents

(2012) Chibeza C. Agley et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Genetically modified species in research: opportunities and challenges for the histology core laboratory

(2012) Alicia K Olivier et al.   JOURNAL OF HISTOTECHNOLOGY

Semi-quantitative immunohistochemical assay versus oncotype DX® qRT-PCR assay for estrogen and progesterone receptors: an independent quality assurance study

(2012) James A Kraus et al.   MODERN PATHOLOGY

Application of Immunohistochemistry in Stereology for Quantitative Assessment of Neural Cell Populations Illustrated in the Göttingen Minipig

(2012) Jack Hou et al.   PLoS One

p53 Staining Correlates With Tumor Type and Location in Sebaceous Neoplasms

(2011) Sara C. Shalin et al.   AMERICAN JOURNAL OF DERMATOPATHOLOGY

Factors Influencing the Degradation of Archival Formalin-Fixed Paraffin-Embedded Tissue Sections

(2011) Ran Xie et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Image Analysis Tools for Evaluation of Microscopic Views of Immunohistochemically Stained Specimen in Medical Research–a Review

(2011) Keerthana Prasad et al.   JOURNAL OF MEDICAL SYSTEMS

Is CFTR-delF508 Really Absent from the Apical Membrane of the Airway Epithelium?

(2011) Lee A. Borthwick et al.   PLoS One

The Use of Immunohistochemistry for Biomarker Assessment—Can It Compete with Other Technologies?

(2011) Robert W. Dunstan et al.   TOXICOLOGIC PATHOLOGY

Analysis of Unbiased Histopathology Data from Rodent Toxicity Studies (or, Are These Groups Different Enough to Ascribe It to Treatment?)

(2011) Tom Holland et al.   TOXICOLOGIC PATHOLOGY

Designing Phenotyping Studies for Genetically Engineered Mice

(2011) C. J. Zeiss et al.   VETERINARY PATHOLOGY

Loss of Cystic Fibrosis Transmembrane Conductance Regulator Function Produces Abnormalities in Tracheal Development in Neonatal Pigs and Young Children

(2010) David K. Meyerholz et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Antibody validation

(2010) Jennifer Bordeaux et al.   BIOTECHNIQUES

Use of Tissue Cross-reactivity Studies in the Development of Antibody-based Biopharmaceuticals

(2010) Michael W. Leach et al.   TOXICOLOGIC PATHOLOGY

Quantitative Comparison of Active and Latent Tuberculosis in the Cynomolgus Macaque Model

(2009) P. L. Lin et al.   INFECTION AND IMMUNITY

A Robust Automated Measure of Average Antibody Staining in Immunohistochemistry Images

(2009) Kingshuk Roy Choudhury et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Synergistic Tissue Counterstaining and Image Segmentation Techniques for Accurate, Quantitative Immunohistochemistry

(2008) Simone P. Zehntner et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY