Differential Responses by Human Respiratory Epithelial Cell Lines to Respiratory Syncytial Virus Reflect Distinct Patterns of Infection Control

The IFN-λ-IFN-λR1-IL-10Rβ Complex Reveals Structural Features Underlying Type III IFN Functional Plasticity

(2017) Juan L. Mendoza et al.   IMMUNITY

Detection of interferon alpha protein reveals differential levels and cellular sources in disease

(2017) Mathieu P. Rodero et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Systematic Analysis of Cell-Type Differences in the Epithelial Secretome Reveals Insights into the Pathogenesis of Respiratory Syncytial Virus–Induced Lower Respiratory Tract Infections

(2017) Yingxin Zhao et al.   JOURNAL OF IMMUNOLOGY

Respiratory syncytial virus infection induces a subset of types I and III interferons in human dendritic cells

(2017) Philippa Hillyer et al.   VIROLOGY

A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3

(2016) Alexa C. Robitaille et al.   Jove-Journal of Visualized Experiments

A Simple Screening Approach To Prioritize Genes for Functional Analysis Identifies a Role for Interferon Regulatory Factor 7 in the Control of Respiratory Syncytial Virus Disease

(2016) Jacqueline U. McDonald et al.   mSystems

The Interleukin-13 Receptor-α1 Chain Is Essential for Induction of the Alternative Macrophage Activation Pathway by IL-13 but Not IL-4

(2015) Faruk Sheikh et al.   Journal of Innate Immunity

Kinetic Differences and Synergistic Antiviral Effects Between Type I and Type III Interferon Signaling Indicate Pathway Independence

(2015) Emily A. Voigt et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Partial Attenuation of Respiratory Syncytial Virus with a Deletion of a Small Hydrophobic Gene Is Associated with Elevated Interleukin-1β Responses

(2015) Ryan F. Russell et al.   JOURNAL OF VIROLOGY

The acetyltransferase HAT1 moderates the NF-κB response by regulating the transcription factor PLZF

(2015) Anthony J. Sadler et al.   Nature Communications

Respiratory Syncytial Virus Uses CX3CR1 as a Receptor on Primary Human Airway Epithelial Cultures

(2015) Sara M. Johnson et al.   PLoS Pathogens

Respiratory Syncytial Virus Nonstructural Proteins Upregulate SOCS1 and SOCS3 in the Different Manner from Endogenous IFN Signaling

(2015) Junwen Zheng et al.   Journal of Immunology Research

High-throughput Quantitative Real-time RT-PCR Assay for Determining Expression Profiles of Types I and III Interferon Subtypes

(2015) Lynnsey A. Renn et al.   Jove-Journal of Visualized Experiments

Interferon-Stimulated Genes: A Complex Web of Host Defenses

(2014) William M. Schneider et al.   Annual Review of Immunology

Simian Virus 40 Large T Antigen Induces IFN-Stimulated Genes through ATR Kinase

(2014) A. Forero et al.   JOURNAL OF IMMUNOLOGY

Interferon lambda 1–3 expression in infants hospitalized for RSV or HRV associated bronchiolitis

(2014) Carla Selvaggi et al.   JOURNAL OF INFECTION

Sustained Activation of Interferon Regulatory Factor 3 during Infection by Paramyxoviruses Requires MDA5

(2014) Nathalie Grandvaux et al.   Journal of Innate Immunity

Ataxia Telangiectasia Mutated Kinase Mediates NF-κB Serine 276 Phosphorylation and Interferon Expression via the IRF7-RIG-I Amplification Loop in Paramyxovirus Infection

(2014) Ling Fang et al.   JOURNAL OF VIROLOGY

High Basal Expression of Interferon-Stimulated Genes in Human Bronchial Epithelial (BEAS-2B) Cells Contributes to Influenza A Virus Resistance

(2014) Lai-Giea Seng et al.   PLoS One

Suppression of Interferon Lambda Signaling by SOCS-1 Results in Their Excessive Production during Influenza Virus Infection

(2014) Haitao Wei et al.   PLoS Pathogens

Causal analysis approaches in Ingenuity Pathway Analysis

(2013) Andreas Krämer et al.   BIOINFORMATICS

Subtypes of type I IFN differentially enhance cytokine expression by suboptimally stimulated CD4+T cells

(2013) Philippa Hillyer et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Direct, Interferon-Independent Activation of the CXCL10 Promoter by NF- B and Interferon Regulatory Factor 3 during Hepatitis C Virus Infection

(2013) J. Brownell et al.   JOURNAL OF VIROLOGY

Respiratory Syncytial Virus and Recurrent Wheeze

(2013)   NEW ENGLAND JOURNAL OF MEDICINE

Novel Inflammatory Markers, Clinical Risk Factors and Virus Type Associated With Severe Respiratory Syncytial Virus Infection

(2013) Christy M. Tabarani et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Expression profiles of human interferon-alpha and interferon-lambda subtypes are ligand- and cell-dependent

(2012) Philippa Hillyer et al.   IMMUNOLOGY AND CELL BIOLOGY

Innate Immune Dysfunction is Associated with Enhanced Disease Severity In Infants with Severe Respiratory Syncytial Virus Bronchiolitis

(2012) Cesar Mella et al.   JOURNAL OF INFECTIOUS DISEASES

Evaluation of viral load in infants hospitalized with bronchiolitis caused by respiratory syncytial virus

(2012) Carolina Scagnolari et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

Advances in understanding respiratory syncytial virus infection in airway epithelial cells and consequential effects on the immune response

(2012) Margarita K. Lay et al.   MICROBES AND INFECTION

Respiratory syncytial virus (RSV) attachment and nonstructural proteins modify the type I interferon response associated with suppressor of cytokine signaling (SOCS) proteins and IFN-stimulated gene-15 (ISG15)

(2012) Elizabeth C Moore et al.   Virology Journal

Identification of nucleolin as a cellular receptor for human respiratory syncytial virus

(2011) Farnoosh Tayyari et al.   NATURE MEDICINE

Lambda Interferon Renders Epithelial Cells of the Respiratory and Gastrointestinal Tracts Resistant to Viral Infections

(2010) M. Mordstein et al.   JOURNAL OF VIROLOGY

Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis

(2010) Harish Nair et al.   LANCET

Monolayer Culture Systems with Respiratory Epithelial Cells for Evaluation of Bacterial Invasiveness

(2010) Yoichi Hirakata et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

A Chimeric A2 Strain of Respiratory Syncytial Virus (RSV) with the Fusion Protein of RSV Strain Line 19 Exhibits Enhanced Viral Load, Mucus, and Airway Dysfunction

(2009) M. L. Moore et al.   JOURNAL OF VIROLOGY

Receptor Density Is Key to the Alpha2/Beta Interferon Differential Activities

(2009) I. Moraga et al.   MOLECULAR AND CELLULAR BIOLOGY

The role of transposable elements in the regulation of IFN-λ1 gene expression

(2009) Scott J. P. Thomson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Infection and maturation of monocyte-derived human dendritic cells by human respiratory syncytial virus, human metapneumovirus, and human parainfluenza virus type 3

(2009) Cyril Le Nouën et al.   VIROLOGY

RSV replication is attenuated by counteracting expression of the suppressor of cytokine signaling (SOCS) molecules

(2009) Koichi Hashimoto et al.   VIROLOGY

Evidence of a Causal Role of Winter Virus Infection during Infancy in Early Childhood Asthma

(2008) Pingsheng Wu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Nonstructural Proteins 1 and 2 of Respiratory Syncytial Virus Suppress Maturation of Human Dendritic Cells

(2008) S. Munir et al.   JOURNAL OF VIROLOGY

Respiratory Syncytial Virus Activates Innate Immunity through Toll-Like Receptor 2

(2008) M. R. Murawski et al.   JOURNAL OF VIROLOGY

Sequential control of Toll-like receptor–dependent responses by IRAK1 and IRAK2

(2008) Tatsukata Kawagoe et al.   NATURE IMMUNOLOGY