Ataxia Telangiectasia Mutated Kinase Mediates NF-κB Serine 276 Phosphorylation and Interferon Expression via the IRF7-RIG-I Amplification Loop in Paramyxovirus Infection

Interferon-Stimulated Genes: A Complex Web of Host Defenses

(2014) William M. Schneider et al.   Annual Review of Immunology

Prion-like Polymerization Underlies Signal Transduction in Antiviral Immune Defense and Inflammasome Activation

(2014) Xin Cai et al.   CELL

RSV-encoded NS2 promotes epithelial cell shedding and distal airway obstruction

(2014) Rachael M. Liesman et al.   JOURNAL OF CLINICAL INVESTIGATION

MDA5 Participates in the Detection of Paramyxovirus Infection and Is Essential for the Early Activation of Dendritic Cells in Response to Sendai Virus Defective Interfering Particles

(2014) J. S. Yount et al.   JOURNAL OF IMMUNOLOGY

8-Oxoguanine DNA Glycosylase-1 Augments Proinflammatory Gene Expression by Facilitating the Recruitment of Site-Specific Transcription Factors

(2014) X. Ba et al.   JOURNAL OF IMMUNOLOGY

ATM regulates NF-κB-dependent immediate-early genes via RelA Ser 276 phosphorylation coupled to CDK9 promoter recruitment

(2014) Ling Fang et al.   NUCLEIC ACIDS RESEARCH

Dynamic Cross Talk Model of the Epithelial Innate Immune Response to Double-Stranded RNA Stimulation: Coordinated Dynamics Emerging from Cell-Level Noise

(2014) Roberto Bertolusso et al.   PLoS One

Mechanisms of MAVS Regulation at the Mitochondrial Membrane

(2013) Jana L. Jacobs et al.   JOURNAL OF MOLECULAR BIOLOGY

CDK9-Dependent Transcriptional Elongation in the Innate Interferon-Stimulated Gene Response to Respiratory Syncytial Virus Infection in Airway Epithelial Cells

(2013) B. Tian et al.   JOURNAL OF VIROLOGY

HCV Infection Induces a Unique Hepatic Innate Immune Response Associated With Robust Production of Type III Interferons

(2012) Emmanuel Thomas et al.   GASTROENTEROLOGY

Respiratory Syncytial Virus Matrix Protein Induces Lung Epithelial Cell Cycle Arrest through a p53 Dependent Pathway

(2012) Tao Bian et al.   PLoS One

Junín Virus Infection Activates the Type I Interferon Pathway in a RIG-I-Dependent Manner

(2012) Cheng Huang et al.   PLoS Neglected Tropical Diseases

MAVS Forms Functional Prion-like Aggregates to Activate and Propagate Antiviral Innate Immune Response

(2011) Fajian Hou et al.   CELL

RelA Ser276 Phosphorylation-Coupled Lys310 Acetylation Controls Transcriptional Elongation of Inflammatory Cytokines in Respiratory Syncytial Virus Infection

(2011) A. R. Brasier et al.   JOURNAL OF VIROLOGY

Distinct Roles for the NF- B RelA Subunit during Antiviral Innate Immune Responses

(2011) S. H. Basagoudanavar et al.   JOURNAL OF VIROLOGY

Interferon-stimulated genes and their antiviral effector functions

(2011) John W Schoggins et al.   Current Opinion in Virology

Defining Emerging Roles for NF-κB in Antivirus Responses: Revisiting the Interferon-β Enhanceosome Paradigm

(2011) Siddharth Balachandran et al.   PLoS Pathogens

Respiratory Viral Infections in Infants: Causes, Clinical Symptoms, Virology, and Immunology

(2010) J. S. Tregoning et al.   CLINICAL MICROBIOLOGY REVIEWS

Simian Virus 40 Activates ATR-Δp53 Signaling To Override Cell Cycle and DNA Replication Control

(2010) Gabor Rohaly et al.   JOURNAL OF VIROLOGY

Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis

(2010) Harish Nair et al.   LANCET

γH2AX: a sensitive molecular marker of DNA damage and repair

(2010) L-J Mah et al.   LEUKEMIA

Bronchiolitis: Recent Evidence on Diagnosis and Management

(2010) J. J. Zorc et al.   PEDIATRICS

ATM Activation by Oxidative Stress

(2010) Z. Guo et al.   SCIENCE

Respiratory Syncytial Virus Induces Oxidative Stress by Modulating Antioxidant Enzymes

(2009) Yashoda M. Hosakote et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Respiratory Syncytial Virus Infection Induces a Reactive Oxygen Species-MSK1-Phospho-Ser-276 RelA Pathway Required for Cytokine Expression

(2009) M. Jamaluddin et al.   JOURNAL OF VIROLOGY

A Nuclear Poly(ADP-Ribose)-Dependent Signalosome Confers DNA Damage-Induced IκB Kinase Activation

(2009) Michael Stilmann et al.   MOLECULAR CELL

The Burden of Respiratory Syncytial Virus Infection in Young Children

(2009) Caroline Breese Hall et al.   NEW ENGLAND JOURNAL OF MEDICINE

Expression of an IKKγ Splice Variant Determines IRF3 and Canonical NF-κB Pathway Utilization in ssRNA Virus Infection

(2009) Ping Liu et al.   PLoS One

Crosstalk between histone modifications during the DNA damage response

(2009) Haico van Attikum et al.   TRENDS IN CELL BIOLOGY

Immunodeficiency in ataxia telangiectasia is correlated strongly with the presence of two null mutations in the ataxia telangiectasia mutated gene

(2008) E. R. Staples et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Roles of ubiquitination in pattern-recognition receptors and type I interferon receptor signaling

(2008) Annie Bibeau-Poirier et al.   CYTOKINE

Structural Mechanism of RNA Recognition by the RIG-I-like Receptors

(2008) Mitsutoshi Yoneyama et al.   IMMUNITY

Simian Virus 40 Large T Antigen Disrupts Genome Integrity and Activates a DNA Damage Response via Bub1 Binding

(2008) J. Hein et al.   JOURNAL OF VIROLOGY

RelA Ser276 Phosphorylation Is Required for Activation of a Subset of NF- B-Dependent Genes by Recruiting Cyclin-Dependent Kinase 9/Cyclin T1 Complexes

(2008) D. E. Nowak et al.   MOLECULAR AND CELLULAR BIOLOGY