The roles of cellular and molecular components of a hematoma at early stage of bone healing

Dexamethasone Enhances Osteogenic Differentiation of Bone Marrow- and Muscle-Derived Stromal Cells and Augments Ectopic Bone Formation Induced by Bone Morphogenetic Protein-2

(2015) Masato Yuasa et al.   PLoS One

Fracture Healing via Periosteal Callus Formation Requires Macrophages for Both Initiation and Progression of Early Endochondral Ossification

(2014) Liza J. Raggatt et al.   AMERICAN JOURNAL OF PATHOLOGY

Plasminogen Activator Inhibitor-1 Is Involved in Impaired Bone Repair Associated with Diabetes in Female Mice

(2014) Li Mao et al.   PLoS One

RANKL Cytokine: From Pioneer of the Osteoimmunology Era to Cure for a Rare Disease

(2013) Nadia Lo Iacono et al.   Clinical & Developmental Immunology

Bone marrow-derived mesenchymal stem cells enhance angiogenesis via their α6β1 integrin receptor

(2013) Bita Carrion et al.   EXPERIMENTAL CELL RESEARCH

L-PRP diminishes bone matrix formation around autogenous bone grafts associated with changes in osteocalcin and PPAR-γ immunoexpression

(2013) G.S. Portela et al.   INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY

In vitro hypertrophy and calcification of human fracture haematoma-derived cells in chondrogenic differentiation

(2013) Takaaki Koga et al.   INTERNATIONAL ORTHOPAEDICS

Improvements of osteoblast adhesion, proliferation, and differentiationin vitrovia fibrin network formation in collagen sponge scaffold

(2013) Beom-Su Kim et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Plasminogen Plays a Crucial Role in Bone Repair

(2013) Naoyuki Kawao et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Effect of platelet rich plasma and platelet rich fibrin on sciatic nerve regeneration in a rat model

(2013) Martina Lichtenfels et al.   MICROSURGERY

Platelet rich plasma extract promotes angiogenesis through the angiopoietin1-Tie2 pathway

(2013) Tadanori Mammoto et al.   MICROVASCULAR RESEARCH

Biological activity of a standardized freeze-dried platelet derivative to be used as cell culture medium supplement

(2013) Anita Muraglia et al.   PLATELETS

CD146+ Human Umbilical Cord Perivascular Cells Maintain Stemness under Hypoxia and as a Cell Source for Skeletal Regeneration

(2013) Wing Pui Tsang et al.   PLoS One

Macrophages Play a Key Role in Angiogenesis and Adipogenesis in a Mouse Tissue Engineering Model

(2013) Heidi Debels et al.   TISSUE ENGINEERING PART A

In Vivo Production of Mesenchymal Stromal Cells After Injection of Autologous Platelet-Rich Plasma Activated by Recombinant Human Soluble Tissue Factor in the Bone Marrow of Healthy Volunteers

(2013) Pierre Philippart et al.   TISSUE ENGINEERING PART A

Activated platelet-rich plasma improves adipose-derived stem cell transplantation efficiency in injured articular cartilage

(2013) Phuc Van Pham et al.   Stem Cell Research & Therapy

Effect of scaffold dilution on migration of mesenchymal stem cells from fibrin hydrogels

(2012) Benjamin W. Hale et al.   AMERICAN JOURNAL OF VETERINARY RESEARCH

Comparative evaluation of MSCs from bone marrow and adipose tissue seeded in PRP-derived scaffold for cartilage regeneration

(2012) Xuetao Xie et al.   BIOMATERIALS

Adult and umbilical cord blood-derived platelet-rich plasma for mesenchymal stem cell proliferation, chemotaxis, and cryo-preservation

(2012) Matthew B. Murphy et al.   BIOMATERIALS

Leukocyte-Platelet-Rich Plasma (L-PRP) Induces an Abnormal Histophenotype in Craniofacial Bone Repair Associated with Changes in the Immunopositivity of the Hematopoietic Clusters of Differentiation, Osteoproteins, and TGF-β1

(2012) Allan Fernando Giovanini et al.   Clinical Implant Dentistry and Related Research

Do the Fibrin Architecture and Leukocyte Content Influence the Growth Factor Release of Platelet Concentrates? An Evidence-based Answer Comparing a Pure Platelet-Rich Plasma (P-PRP) Gel and a Leukocyte- and Platelet-Rich Fibrin (L-PRF)

(2012) David M. Dohan Ehrenfest et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

The Role of Leukocytes from L-PRP/L-PRF in Wound Healing and Immune Defense: New Perspectives

(2012) Tomasz Bielecki et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Plasma clots gelled by different amounts of calcium for stem cell delivery

(2012) Jan Gessmann et al.   LANGENBECKS ARCHIVES OF SURGERY

A Platelet-Rich Plasma-Based Membrane as a Periosteal Substitute with Enhanced Osteogenic and Angiogenic Properties: A New Concept for Bone Repair

(2012) Rania M. El Backly et al.   TISSUE ENGINEERING PART A

Enhanced Vascularization by Controlled Release of Platelet-Rich Plasma Impregnated in Biodegradable Gelatin Hydrogel

(2011) Jiro Kurita et al.   ANNALS OF THORACIC SURGERY

Osteoimmunology: cytokines and the skeletal system

(2011) Seoung-Hoon Lee et al.   BMB Reports

The ratio of VEGF/PEDF expression in bone marrow mesenchymal stem cells regulates neovascularization

(2011) Wei Fan et al.   DIFFERENTIATION

Plasminogen/Plasmin Modulates Bone Metabolism by Regulating the Osteoblast and Osteoclast Function

(2011) Yosuke Kanno et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Osteal macrophages promote in vivo intramembranous bone healing in a mouse tibial injury model

(2011) Kylie A Alexander et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Mandibular Hematoma Cells as a Potential Reservoir for Osteoprogenitor Cells in Fractures

(2011) Takumi Hasegawa et al.   JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY

What Is Platelet-Rich Plasma?

(2011) Steven P. Arnoczky et al.   OPERATIVE TECHNIQUES IN SPORTS MEDICINE

Hypoxia Inhibits Osteogenesis in Human Mesenchymal Stem Cells through Direct Regulation of RUNX2 by TWIST

(2011) Der-Chih Yang et al.   PLoS One

Mesenchymal Stem Cells Expressing Insulin-like Growth Factor-I (MSCIGF) Promote Fracture Healing and Restore New Bone Formation in Irs1 Knockout Mice: Analyses of MSCIGF Autocrine and Paracrine Regenerative Effects

(2011) Froilán Granero-Moltó et al.   STEM CELLS

Effects of a highly concentrated platelet-rich plasma on the bone repair using non-critical defects in the calvaria of rabbits

(2010) Marco Antonio de Oliveira Filho et al.   Acta Cirurgica Brasileira

Platelet-Rich Plasma in Muscle Healing

(2010) Paolo Borrione et al.   AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION

Fibrinopeptides A and B release in the process of surface fibrin formation

(2010) T. Riedel et al.   BLOOD

Cross talk between the bone and immune systems: osteoclasts function as antigen-presenting cells and activate CD4+ and CD8+ T cells

(2010) H. Li et al.   BLOOD

Oxygen in Stem Cell Biology: A Critical Component of the Stem Cell Niche

(2010) Ahmed Mohyeldin et al.   Cell Stem Cell

The role of thrombin activatable fibrinolysis inhibitor and factor XI in platelet-mediated fibrinolysis resistance: a thromboelastographic study in whole blood

(2010) C. CARRIERI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Osteogenic differentiation of human mesenchymal stromal cells is promoted by a leukocytes containing fibrin matrix

(2010) Dominik Seybold et al.   LANGENBECKS ARCHIVES OF SURGERY

Complement activation on platelets: Implications for vascular inflammation and thrombosis

(2010) Ellinor I. Peerschke et al.   MOLECULAR IMMUNOLOGY

TGF-β1 As Possible Link between Loss of Bone Mineral Density and Chronic Inflammation

(2010) Sabrina Ehnert et al.   PLoS One

The Effect of Platelet-Rich Plasma In Vitro on Primary Cells: Rat Osteoblast-like Cells and Human Endothelial Cells

(2010) Robert E.C.M. Mooren et al.   TISSUE ENGINEERING PART A

Polyphosphates: a link between platelet activation, intrinsic coagulation and inflammation?

(2010) Paola EJ van der Meijden et al.   Expert Review of Hematology

Selective and Specific Macrophage Ablation Is Detrimental to Wound Healing in Mice

(2009) Rita Mirza et al.   AMERICAN JOURNAL OF PATHOLOGY

In Vitro Inhibition of Factor XIII Retards Clot Formation, Reduces Clot Firmness, and Increases Fibrinolytic Effects in Whole Blood

(2009) Csilla Jámbor et al.   ANESTHESIA AND ANALGESIA

Platelet α-granules: Basic biology and clinical correlates

(2009) Price Blair et al.   BLOOD REVIEWS

Regulation of Osteogenesis-Angiogenesis Coupling by HIFs and VEGF

(2009) Ernestina Schipani et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Cellular composition of the initial fracture hematoma compared to a muscle hematoma: A study in sheep

(2009) Katharina Schmidt-Bleek et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

The structure and function of platelet integrins

(2009) J. S. BENNETT et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Hypoxia inducible factors regulate pluripotency and proliferation in human embryonic stem cells cultured at reduced oxygen tensions

(2009) Catherine E Forristal et al.   REPRODUCTION

Application of Platelet-Rich Plasma in Plastic Surgery: Clinical and In Vitro Evaluation

(2009) Valerio Cervelli et al.   TISSUE ENGINEERING PART C-METHODS

Autologous platelets and leukocytes can improve healing of infected high-energy soft tissue injury

(2009) Agata Cieslik-Bielecka et al.   TRANSFUSION AND APHERESIS SCIENCE

Classification of platelet concentrates: from pure platelet-rich plasma (P-PRP) to leucocyte- and platelet-rich fibrin (L-PRF)

(2009) David M. Dohan Ehrenfest et al.   TRENDS IN BIOTECHNOLOGY

Fracture Healing in Mice Deficient in Plasminogen Activator Inhibitor-1

(2008) Charles H. Rundle et al.   CALCIFIED TISSUE INTERNATIONAL

Altered fibrin clot structure and function in the healthy first-degree relatives of subjects with intermittent claudication

(2008) Neeraj Bhasin et al.   JOURNAL OF VASCULAR SURGERY

Foreign body reaction to biomaterials

(2008) James M. Anderson et al.   SEMINARS IN IMMUNOLOGY

Platelet-Rich Plasma and Fibrin Glue–Coated Bioactive Ceramics Enhance Growth and Differentiation of Goat Bone Marrow–Derived Stem Cells

(2008) Manitha B. Nair et al.   TISSUE ENGINEERING PART A

Thrombin generation, fibrin clot formation and hemostasis

(2008) Alisa S. Wolberg et al.   TRANSFUSION AND APHERESIS SCIENCE

Insulin-like growth factor I releasing silk fibroin scaffolds induce chondrogenic differentiation of human mesenchymal stem cells

(2007) Lorenz Uebersax et al.   JOURNAL OF CONTROLLED RELEASE

Antimicrobial activity of platelet-leukocyte gel againstStaphylococcus aureus

(2007) Dirk Jan F. Moojen et al.   JOURNAL OF ORTHOPAEDIC RESEARCH