Platelets kill bacteria by bridging innate and adaptive immunity via platelet factor 4 and FcγRIIA

DeconvolutionLab2: An open-source software for deconvolution microscopy

(2017) Daniel Sage et al.   METHODS

Cytotoxic T Cells Use Mechanical Force to Potentiate Target Cell Killing

(2016) Roshni Basu et al.   CELL

Escherichia coli induces platelet aggregation in an FcγRIIa-dependent manner

(2016) R. D. Moriarty et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Human platelet activation by Escherichia coli: roles for FcγRIIA and integrin αIIbβ3

(2016) Callum N. Watson et al.   PLATELETS

Platelet geometry sensing spatially regulates  -granule secretion to enable matrix self-deposition

(2015) Y. Sakurai et al.   BLOOD

Platelet secretion: From haemostasis to wound healing and beyond

(2015) Ewelina M. Golebiewska et al.   BLOOD REVIEWS

The platelet Fc receptor, FcγRIIa

(2015) Jianlin Qiao et al.   IMMUNOLOGICAL REVIEWS

Bacteria-induced intracellular signalling in platelets

(2015) Archie McNicol   PLATELETS

The expanding field of platelet–bacterial interconnections

(2015) Steven W. Kerrigan   PLATELETS

Platelet Activation and Thrombus Formation over IgG Immune Complexes Requires Integrin αIIbβ3 and Lyn Kinase

(2015) Huiying Zhi et al.   PLoS One

Polyphosphates form antigenic complexes with platelet factor 4 (PF4) and enhance PF4-binding to bacteria

(2015) Sven Brandt et al.   THROMBOSIS AND HAEMOSTASIS

Platelets and Infections – Complex Interactions with Bacteria

(2015) Hind Hamzeh-Cognasse et al.   Frontiers in Immunology

Are Platelets Cells? And if Yes, are They Immune Cells?

(2015) Olivier Garraud et al.   Frontiers in Immunology

Binding of anti-platelet factor 4/heparin antibodies depends on the thermodynamics of conformational changes in platelet factor 4

(2014) M. Kreimann et al.   BLOOD

Amplification of bacteria-induced platelet activation is triggered by Fc RIIA, integrin  IIb 3, and platelet factor 4

(2014) M. Arman et al.   BLOOD

Platelets: at the nexus of antimicrobial defence

(2014) Michael R. Yeaman   NATURE REVIEWS MICROBIOLOGY

Characterisation of the conformational changes in platelet factor 4 induced by polyanions: towards in vitro prediction of antigenicity

(2014) Sven Brandt et al.   THROMBOSIS AND HAEMOSTASIS

Platelet immunology in fungal infections

(2014) Cornelia Speth et al.   THROMBOSIS AND HAEMOSTASIS

Micropatterned array to assess the interaction of single platelets with platelet factor 4-heparin-IgG complexes

(2014) Krystin Krauel et al.   THROMBOSIS AND HAEMOSTASIS

Platelets and Infection – An Emerging Role of Platelets in Viral Infection

(2014) Alice Assinger   Frontiers in Immunology

Fabrication of Quantum Dot Microarrays Using Electron Beam Lithography for Applications in Analyte Sensing and Cellular Dynamics

(2013) Raghavendra Palankar et al.   ACS Nano

Platelet factor 4 binding to lipid A of Gram-negative bacteria exposes PF4/heparin-like epitopes

(2012) K. Krauel et al.   BLOOD

Granule exocytosis is required for platelet spreading: differential sorting of  -granules expressing VAMP-7

(2012) C. G. Peters et al.   BLOOD

Human platelets efficiently kill IgG-opsonizedE. coli

(2012) Anum H. Riaz et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Platelet Factor 4 and Duffy Antigen Required for Platelet Killing of Plasmodium falciparum

(2012) B. J. McMorran et al.   SCIENCE

Platelets and the innate immune system: mechanisms of bacterial-induced platelet activation

(2011) D. COX et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Platelets: versatile effector cells in hemostasis, inflammation, and the immune continuum

(2011) Adriana Vieira-de-Abreu et al.   Seminars in Immunopathology

Novel Anti-bacterial Activities of β-defensin 1 in Human Platelets: Suppression of Pathogen Growth and Signaling of Neutrophil Extracellular Trap Formation

(2011) Bjoern F. Kraemer et al.   PLoS Pathogens

Normal ranges of angiogenesis regulatory proteins in human platelets

(2010) Jon E. Peterson et al.   AMERICAN JOURNAL OF HEMATOLOGY

Mechanism of Outside-In α IIb β 3 -Mediated Activation of Human Platelets by the Colonizing Bacterium, Streptococcus gordonii

(2010) Ciara Keane et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Platelet factor 4 binds to bacteria, inducing antibodies cross-reacting with the major antigen in heparin-induced thrombocytopenia

(2010) K. Krauel et al.   BLOOD

Internalization of IgG-Coated Targets Results in Activation and Secretion of Soluble CD40 Ligand and RANTES by Human Platelets

(2010) Adam J. Antczak et al.   Clinical and Vaccine Immunology

Immobilisation of living bacteria for AFM imaging under physiological conditions

(2010) Rikke Louise Meyer et al.   ULTRAMICROSCOPY

Platelet α-granules: Basic biology and clinical correlates

(2009) Price Blair et al.   BLOOD REVIEWS

Platelet Polyphosphates Are Proinflammatory and Procoagulant Mediators In Vivo

(2009) Felicitas Müller et al.   CELL

Platelet–bacterial interactions

(2009) Steven W. Kerrigan et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Identification of Fc RIIa as the ITAM-bearing receptor mediating  IIb 3 outside-in integrin signaling in human platelets

(2008) B. Boylan et al.   BLOOD

Platelet Antistaphylococcal Responses Occur through P2X1 and P2Y12 Receptor-Induced Activation and Kinocidin Release

(2008) D. A. Trier et al.   INFECTION AND IMMUNITY