Staphylococcus aureus- induced complement activation promotes tissue factor-mediated coagulation

Dangerous liaisons: complement, coagulation, and kallikrein/kinin cross-talk act as a linchpin in the events leading to thromboinflammation

(2016) Kristina N. Ekdahl et al.   IMMUNOLOGICAL REVIEWS

Discovery of functionally selective C5aR2 ligands: novel modulators of C5a signalling

(2016) Daniel E Croker et al.   IMMUNOLOGY AND CELL BIOLOGY

Quantification of “bacterial load” in late-onset neonatal sepsis using molecular techniques

(2016) J Davis et al.   ARCHIVES OF DISEASE IN CHILDHOOD

The key roles of complement and tissue factor inEscherichia coli-induced coagulation in human whole blood

(2015) A. Landsem et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Endothelial barrier dysfunction in septic shock

(2015) S. M. Opal et al.   JOURNAL OF INTERNAL MEDICINE

Sepsis: Current Dogma and New Perspectives

(2014) Clifford S. Deutschman et al.   IMMUNITY

Mortality Related to Severe Sepsis and Septic Shock Among Critically Ill Patients in Australia and New Zealand, 2000-2012

(2014) Kirsi-Maija Kaukonen et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Improved Sensitivity for Molecular Detection of Bacterial and Candida Infections in Blood

(2014) Andrea Bacconi et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Double Blockade of CD14 and Complement C5 Abolishes the Cytokine Storm and Improves Morbidity and Survival in Polymicrobial Sepsis in Mice

(2014) M. Huber-Lang et al.   JOURNAL OF IMMUNOLOGY

Combined Inhibition of Complement and CD14 Efficiently Attenuated the Inflammatory Response Induced by Staphylococcus aureus in a Human Whole Blood Model

(2014) E. W. Skjeflo et al.   JOURNAL OF IMMUNOLOGY

Heterogeneity of Host TLR2 Stimulation by Staphylocoocus aureus Isolates

(2014) Dina Hilmi et al.   PLoS One

Benchmarking the Incidence and Mortality of Severe Sepsis in the United States*

(2013) David F. Gaieski et al.   CRITICAL CARE MEDICINE

Combined Inhibition of Complement (C5) and CD14 Markedly Attenuates Inflammation, Thrombogenicity, and Hemodynamic Changes in Porcine Sepsis

(2013) A. Barratt-Due et al.   JOURNAL OF IMMUNOLOGY

Thrombin generates previously unidentified C5 products that support the terminal complement activation pathway

(2012) M. J. Krisinger et al.   BLOOD

Staphylococcus aureus Secretes Coagulase and von Willebrand Factor Binding Protein to Modify the Coagulation Cascade and Establish Host Infections

(2012) Molly McAdow et al.   Journal of Innate Immunity

After Xigris, researchers look to new targets to combat sepsis

(2012) Sarah C P Williams   NATURE MEDICINE

Complement activation in septic baboons detected by neoepitope-specific assays for C3b/iC3b/C3c, C5a and the terminal C5b-9 complement complex (TCC)

(2010) T. E. MOLLNES et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Inflammation and coagulation

(2010) Marcel Levi et al.   CRITICAL CARE MEDICINE

TLR 2 and CD14 Mediate Innate Immunity and Lung Inflammation to Staphylococcal Panton-Valentine Leukocidin In Vivo

(2010) A. Zivkovic et al.   JOURNAL OF IMMUNOLOGY

High Levels of mecA DNA Detected by a Quantitative Real-Time PCR Assay Are Associated with Mortality in Patients with Methicillin-Resistant Staphylococcus aureus Bacteremia

(2009) Y.-C. Ho et al.   JOURNAL OF CLINICAL MICROBIOLOGY

The many faces of tissue factor

(2009) N. MACKMAN   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Complexity of complement activation in sepsis

(2008) Maciej M. Markiewski et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Cellular trafficking of lipoteichoic acid and Toll-like receptor 2 in relation to signaling; role of CD14 and CD36

(2008) Nadra J. Nilsen et al.   JOURNAL OF LEUKOCYTE BIOLOGY

TLR SIGNALING PATHWAY IN PATIENTS WITH SEPSIS

(2008) Reinaldo Salomão et al.   SHOCK