Article
Chemistry, Multidisciplinary
Jacobs H. Jordan, Henry S. Ashbaugh, Joel T. Mague, Bruce C. Gibb
Summary: There are still many unresolved questions regarding the supramolecular properties of ions in water, and the mathematical models used by supramolecular chemists do not adequately account for screening effects. The study shows that both screening and competitive binding have significant impacts on affinity in buffered solutions, especially when the ionic strength changes significantly. The competitive mathematical model proposed in the study suggests that competitive binding to the host is a major factor for binding attenuation in buffer systems, outweighing the effect of screening.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Chemistry, Physical
Hyejin Kwon, Carson J. Bruns
Summary: Researchers have discovered and characterized a family of all-hydrocarbon, all-p-conjugated [n]cycloparaphenylene-PAH host-guest complexes. They have built a theoretical framework to select these complexes and predict their stabilities. This research offers new opportunities for bespoke PAH separation or remediation materials.
Article
Chemistry, Multidisciplinary
Wujing Xian, Matthew R. Hennefarth, Michelle W. Lee, Tran Do, Ernest Y. Lee, Anastassia N. Alexandrova, Gerard C. L. Wong
Summary: AMPs preferentially permeate prokaryotic membranes via electrostatic binding and membrane remodeling. High salt suppresses this action, but histidines in marine AMPs can interact with salt ions to neutralize phosphate charge and facilitate pore formation.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Nanoscience & Nanotechnology
Lukas M. Gockel, Martin Heyes, Honglian Li, Abdullah Al Nahain, Christian Gorzelanny, Martin Schlesinger, Stefan Holdenrieder, Jin-Ping Li, Vito Ferro, Gerd Bendas
Summary: By synthesizing heparin mimetic polymers, the limitations associated with LMWH have been overcome, showing potential anti-tumor effects in cancer cell metastasis.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Review
Chemistry, Multidisciplinary
Weichen Wei
Summary: Hofmeister effects have a significant impact on physicochemical and biochemical processes in nanoscience. Various applications have been developed based on Hofmeister effects, including hydrogel/aerogel engineering, battery design, nanosynthesis, nanomotors, ion sensors, supramolecular chemistry, colloid and interface science, nanomedicine, and transport behaviors. This review systematically introduces and summarizes the progress of applying Hofmeister effects in nanoscience, aiming to provide a comprehensive guideline for designing more useful Hofmeister effects-based nanosystems in the future.
Article
Polymer Science
Shuang Wei, Zechuan Zhang, Weibin Dong, Ting Liang, Junyi Ji, Wen Tian, Shuai Tan, Qiang Zhao, Caihong Wang, Yong Wu
Summary: Ionic species play an important role in the phase separation behavior of PNIPAm in aqueous solutions, with different ions having varying effects on clouding temperatures. Particularly, the structure of azobenzene molecules under visible light irradiation affects the temperature response of PNIPAm.
MACROMOLECULAR RAPID COMMUNICATIONS
(2021)
Review
Biochemistry & Molecular Biology
Yanming Sun, Shuai Wang, Bingwei Liu, Wei Hu, Ying Zhu
Summary: Traumatic brain injury is caused by external forces acting on the head, leading to immediate and long-term harmful effects. Neuroinflammatory responses mediated through the microbiota-gut-brain axis play a critical role in exacerbating the primary injury. The aryl hydrocarbon receptor (AhR) facilitates communication between the gut microbiota and the brain through recognizing specific ligands, such as tryptophan metabolites. These interactions have significant effects on the central nervous system (CNS) and are mediated through immune, metabolic, and neural signaling mechanisms. This review emphasizes the co-metabolism of tryptophan in the gut microbiota and the signaling pathway mediated by AHR following TBI, as well as potential intervention targets.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Physical
Hayden Robertson, Joshua D. Willott, Kasimir P. Gregory, Edwin C. Johnson, Isaac J. Gresham, Andrew R. J. Nelson, Vincent S. J. Craig, Stuart W. Prescott, Robert Chapman, Grant B. Webber, Erica J. Wanless
Summary: This study provides experimental evidence for the impact of ion hydrophobicity on specific ion effects and reveals the interaction between ion-specific and hydrotropic effects. It is found that changing the hydrophobicity of the ions results in the formation of bundle-like structures in the polymer system, and the ion hydrophobicity is related to its hydration ability.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Chemistry, Physical
Thomas Bourke, Kasimir P. Gregory, Alister J. Page
Summary: The origins and behaviour of specific ion effects have been extensively studied in water and nonaqueous molecular solvents. However, the impacts of specific ion effects on more complex solvents, such as nanostructured ionic liquids, are still unclear. This study hypothesizes that the influence of dissolved ions on the hydrogen bonding in nanostructured ionic liquid PAN constitutes a specific ion effect.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2023)
Article
Spectroscopy
Jiayu Zeng, Yufeng Zhang, Chao Huang, Longjiang Li, Bixue Zhu, Dongmei Chen
Summary: By utilizing the Hofmeister effect between protein molecules and a cesium iodide solution, the SERS signals of proteins with low scattering cross-sections were optimized for label-free determination. The combination of principal component analysis and molecular dynamics simulations provided comprehensive analysis and insight into the interaction mechanism. The internal standard of water vibrational peak was used for quantifying protein content with a strong linear relationship between peak intensity and concentration.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Review
Chemistry, Multidisciplinary
Meagan A. Beatty, Fraser Hof
Summary: Synthetic molecular recognition systems are increasingly utilized in solving applied problems in the life sciences. This tutorial review highlights the programming of host-guest molecular recognition in water, with examples and lessons focused on generalizable themes. It also surveys recent advances in host-guest chemistry within living cells and organisms.
CHEMICAL SOCIETY REVIEWS
(2021)
Review
Cell Biology
Johannes Westman, Sergio Grinstein
Summary: The ability of phagosomes to halt microbial growth is closely linked to their ability to acidify their luminal pH, but certain pathogens can survive and replicate inside phagosomes by targeting the pH-regulatory machinery of host cells to survive or escape.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Gloria Tobajas-Curiel, Qingqing Sun, Jeremy K. M. Sanders, Pablo Ballester, Christopher A. Hunter
Summary: This study used chemical double mutant cycles to measure the interaction between a N-methyl pyridinium cation and a pi-box in a calix[4]pyrrole receptor. The cation-pi interaction was found to be attractive (-11 kJ mol-1), but it was 7 kJ mol-1 less favorable than the corresponding aromatic interaction with the isosteric but uncharged tolyl group. The same method was also used to measure the interaction of a pi-box in the calix[4]pyrrole receptor with a cationic N-methyl pyridinium group and neutral isosteric analogues in water.
CHEMICAL COMMUNICATIONS
(2023)
Article
Ecology
Jason Cosens Walsman, Alexander Thomas Strauss, Spencer Ryan Hall
Summary: Parasites can both decrease and increase host density by causing mortality and affecting host foraging behavior. This study integrates trait measurements, a resource-host-parasite model, and experimental epidemics to explore the effects of parasites on host density. The findings demonstrate the tension between density-mediated and trait-mediated effects of parasites, and reveal the importance of resource feedback in determining host density during epidemics.
FUNCTIONAL ECOLOGY
(2022)
Article
Green & Sustainable Science & Technology
Liyun Liu, Zhenzhi Zhao, Mingming Zhang, Changxiao Zhou, Dequn Zhou
Summary: This study used Chinese provincial-level data to provide statistical evidence for the moderating effect of environmental regulations on the reverse green technology spillover of outward foreign direct investment. The results showed that well-designed environmental regulations can amplify the reverse green technology spillover brought by OFDI, with regional differences in the moderating effect.
JOURNAL OF CLEANER PRODUCTION
(2021)
Review
Chemistry, Multidisciplinary
Kaiya Wang, Jacobs H. Jordan, Krishnasamy Velmurugan, Xueqi Tian, Minzan Zuo, Xiao-Yu Hu, Leyong Wang
Summary: Pillarenes, with their useful features such as rigidity, capaciousness, hydrophobic cavities, and exposed functional groups, have become increasingly popular since their discovery in 2008. This Minireview focuses on the use of functionalized Pillarenes and their assembled supramolecular materials in catalysis, providing insights into their mechanisms and potential applications. Subdivided topics include catalysis promoted by the Pillarene rim/cavity, Pillarene-based nanomaterials, and Pillarene-based polymeric materials, making it the first comprehensive overview on Pillarene-based catalysis.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Review
Chemistry, Multidisciplinary
Kaiya Wang, Xueqi Tian, Jacobs H. Jordan, Krishnasamy Velmurugan, Leyong Wang, Xiao-Yu Hu
Summary: This article reviews the emerging applications of pillararene architectures in catalysis and provides clues for future development in this research field.
CHINESE CHEMICAL LETTERS
(2022)
Article
Chemistry, Physical
Jacobs H. Jordan, Huai N. Cheng, Michael W. Easson, Wei Yao, Brian D. Condon, Bruce C. Gibb
Summary: Research on using cellulose nanomaterials to improve the performance of cottonseed protein as a paper strength agent found that the addition of nanocellulose improved the elongation at break, tensile strength, and modulus of treated paper products. The cottonseed protein/nanocellulose composites interacted with the filter paper fibers, enhancing the dry strength of the paper.
Article
Materials Science, Paper & Wood
Robert T. Mackin, Krystal R. Fontenot, J. Vincent Edwards, Nicolette T. Prevost, Casey Grimm, Brian D. Condon, Falk Liebner, Jacobs H. Jordan, Michael W. Easson, Alfred D. French
Summary: In this study, a peptide-cellulose conjugate biosensor based on TEMPO-oxidized nanofibrillated cellulose (tNFC) was synthesized and characterized for detecting elevated levels of human neutrophil elastase (HNE) in chronic wounds. The biosensor showed high peptide incorporation and a relatively small crystallite size, leading to a large specific surface area and high porosity. It is a sensitive system for detecting elevated protease levels in humans.
Article
Chemistry, Multidisciplinary
Jacobs H. Jordan, Henry S. Ashbaugh, Joel T. Mague, Bruce C. Gibb
Summary: There are still many unresolved questions regarding the supramolecular properties of ions in water, and the mathematical models used by supramolecular chemists do not adequately account for screening effects. The study shows that both screening and competitive binding have significant impacts on affinity in buffered solutions, especially when the ionic strength changes significantly. The competitive mathematical model proposed in the study suggests that competitive binding to the host is a major factor for binding attenuation in buffer systems, outweighing the effect of screening.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Chemistry, Multidisciplinary
Hannah R. Aziz, Wei Yao, Jacobs H. Jordan, Bruce C. Gibb
Summary: The small size and high cohesiveness of water make water-mediated interactions context dependent. Through studying a cavitand host called TMAX-Cl (2), researchers found that the binding strength to non-polar hydrophobes is weak, while the binding strength to anions is relatively strong. These findings contribute to a better understanding of water-mediated interactions and the supramolecular properties of TMAX-Cl (2).
SUPRAMOLECULAR CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Robert T. Mackin, Krystal R. Fontenot, Judson Vincent Edwards, Nicolette T. Prevost, Jacobs H. Jordan, Michael W. Easson, Brian D. Condon, Alfred D. French
Summary: Peptide-cellulose conjugates designed as optical protease sensors have potential applications in point-of-care (POC) detection. Nanocellulose, with its biocompatibility and high specific surface area, serves as a suitable transducer surface for sensitive detection of dilute biomarkers. Computational models were used to study the relationship between the sensor molecule and the transducer surface, providing insights for enhanced sensor activity design.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Polymer Science
Jacobs H. Jordan, Michael W. Easson, Huai N. Cheng, Brian D. Condon
Summary: The use of lignin-containing cellulose nanofibers and cottonseed protein as additives can improve the dry strength of filter paper, with the best results obtained using 10% protein solution and 2% nanofibers as additives.
Article
Chemistry, Multidisciplinary
Matthew Blake Hillyer, Jacobs H. Jordan, Sunghyun Nam, Michael W. Easson, Brian D. Condon
Summary: Researchers used silver nanoparticles immobilized within cotton fabric as a catalyst to successfully degrade azo dyes in water. The catalyst exhibited excellent durability and reusability, and showed high degradation capacity for different types of azo dyes.
Article
Chemistry, Multidisciplinary
Sunghyun Nam, Michael Easson, Jacobs H. H. Jordan, Zhongqi He, Hailin Zhang, Michael Santiago Cintron, SeChin Chang
Summary: Cotton gin waste, which is abundantly generated and has limited disposal options, has been explored as a potential source material for synthesizing and hosting silver nanoparticles. The noncellulosic components of cotton gin waste act as reducing agents, converting silver ions into silver atoms, while the porous structure of the waste facilitates controlled particle growth. By heat treating cotton gin waste powder in an aqueous silver precursor solution, silver nanoparticles can be synthesized in situ without the need for additional chemical agents. These silver nanoparticle-filled waste could be utilized for novel antimicrobial and antifungal applications.
Article
Materials Science, Paper & Wood
Jacobs H. Jordan, Michael W. Easson, Stephanie Thompson, Qinglin Wu, Brian D. Condon
Summary: Agricultural waste and residues, such as cotton gin trash and cotton gin motes, were used to prepare lignin-containing cellulose nanofibers with gradient degrees of lignin content. The physical properties of the nanofibers were affected by the lignin content and other components, impacting thermal stability and crystallinity. The degree of polymerization was smaller after processing, with differences based on the source material, resulting in slightly different suspension viscoelastic behavior.
Article
Chemistry, Multidisciplinary
Jacobs H. Jordan, Michael W. Easson, Brian D. Condon
Article
Nanoscience & Nanotechnology
Michael W. Easson, Jacobs H. Jordan, John M. Bland, Doug J. Hinchliffe, Brian D. Condon
ACS APPLIED NANO MATERIALS
(2020)
Article
Materials Science, Textiles
Michael W. Easson, Jacobs Harris Jordan, SeChin Chang, John M. Bland, Brian Douglas Condon
JOURNAL OF ENGINEERED FIBERS AND FABRICS
(2020)
Article
Chemistry, Multidisciplinary
Paolo Suating, Thong T. Nguyen, Nicholas E. Ernst, Yang Wang, Jacobs H. Jordan, Corinne L. D. Gibb, Henry S. Ashbaugh, Bruce C. Gibb
