Melatonin disturbs SUMOylation-mediated crosstalk between c-Myc and nestin via MT1 activation and promotes the sensitivity of paclitaxel in brain cancer stem cells

Characteristics, Properties and Analytical Methods of Paclitaxel: A Review

(2018) Renata Carolina Alves et al.   CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY

Melatonin Inhibits Glioblastoma Stem-like cells through Suppression of EZH2-NOTCH1 Signaling Axis

(2017) Xiangrong Zheng et al.   International Journal of Biological Sciences

Paclitaxel: What has been done and the challenges remain ahead

(2017) Ezequiel Bernabeu et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

SUMO-modified insulin-like growth factor 1 receptor (IGF-1R) increases cell cycle progression and cell proliferation

(2017) Yingbo Lin et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Androgen induces G3BP2 and SUMO-mediated p53 nuclear export in prostate cancer

(2017) D Ashikari et al.   ONCOGENE

Preclinical studies for the combination of paclitaxel and curcumin in cancer therapy

(2017) Yumeng Wei et al.   ONCOLOGY REPORTS

SUMO, a small, but powerful, regulator of double-strand break repair

(2017) Alexander J. Garvin et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Antitumor effectiveness of a combined therapy with a new cucurbitacin B derivative and paclitaxel on a human lung cancer xenograft model

(2017) Lucas Lourenço Marostica et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Melatonin, a novel selective ATF-6 inhibitor, induces human hepatoma cell apoptosis through COX-2 downregulation

(2017) Li-Jia Bu et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Nac1 promotes self-renewal of embryonic stem cells through direct transcriptional regulation of c-Myc

(2017) Yan Ruan et al.   Oncotarget

MicroRNA-128 suppresses paclitaxel-resistant lung cancer by inhibiting MUC1-C and BMI-1 in cancer stem cells

(2017) Hyebin Koh et al.   Oncotarget

The p38 signaling pathway mediates quiescence of glioma stem cells by regulating epidermal growth factor receptor trafficking

(2017) Akio Soeda et al.   Oncotarget

c-Myc is Required for BRAFV600E-Induced Epigenetic Silencing by H3K27me3 in Tumorigenesis

(2017) Yiping Qu et al.   Theranostics

DNA Methylation, Nuclear Organization, and Cancer

(2017) Bhavani P. Madakashira et al.   Frontiers in Genetics

The potential therapeutic effect of melatonin on human ovarian cancer by inhibition of invasion and migration of cancer stem cells

(2017) Maryam Akbarzadeh et al.   Scientific Reports

Decursin enhances TRAIL-induced apoptosis through oxidative stress mediated- endoplasmic reticulum stress signalling in non-small cell lung cancers

(2016) Jaekwang Kim et al.   BRITISH JOURNAL OF PHARMACOLOGY

H3K36 methyltransferases as cancer drug targets: rationale and perspectives for inhibitor development

(2016) David S Rogawski et al.   Future Medicinal Chemistry

Myc/Mycn-mediated glycolysis enhances mouse spermatogonial stem cell self-renewal

(2016) Mito Kanatsu-Shinohara et al.   GENES & DEVELOPMENT

Targeting cancer stem-like cells in glioblastoma and colorectal cancer through metabolic pathways

(2016) U.D. Kahlert et al.   INTERNATIONAL JOURNAL OF CANCER

Melatonin enhances hyperthermia-induced apoptotic cell death in human leukemia cells

(2016) Carlos Quintana et al.   JOURNAL OF PINEAL RESEARCH

Melatonin inhibits tumorigenicity of glioblastoma stem-like cells via the AKT-EZH2-STAT3 signaling axis

(2016) Xueran Chen et al.   JOURNAL OF PINEAL RESEARCH

The RelA/cRel nuclear factor-κB (NF-κB) dimer, crucial for inflammation resolution, mediates the transcription of the key enzyme in melatonin synthesis in RAW 264.7 macrophages

(2016) Sandra Marcia Muxel et al.   JOURNAL OF PINEAL RESEARCH

Melatonin as an antioxidant: under promises but over delivers

(2016) Russel J. Reiter et al.   JOURNAL OF PINEAL RESEARCH

Oncogenic roles and drug target of CXCR4/CXCL12 axis in lung cancer and cancer stem cell

(2016) Zhidong Wang et al.   TUMOR BIOLOGY

The Progress and Prospects of Putative Biomarkers for Liver Cancer Stem Cells in Hepatocellular Carcinoma

(2016) Yan Xiang et al.   Stem Cells International

Inhibition of nestin suppresses stem cell phenotype of glioblastomas through the alteration of post-translational modification of heat shock protein HSPA8/HSC71

(2015) Yoko Matsuda et al.   CANCER LETTERS

Nestin as a marker of cancer stem cells

(2015) Jakub Neradil et al.   CANCER SCIENCE

SUMO wrestles down myc

(2015) R Jürgen Dohmen   CELL CYCLE

Melatonin: an ancient molecule that makes oxygen metabolically tolerable

(2015) Lucien C. Manchester et al.   JOURNAL OF PINEAL RESEARCH

Human Mesenchymal Stem Cells Are Resistant to Paclitaxel by Adopting a Non-Proliferative Fibroblastic State

(2015) Dale B. Bosco et al.   PLoS One

Glioblastoma: Molecular Pathways, Stem Cells and Therapeutic Targets

(2015) Meena Jhanwar-Uniyal et al.   Cancers

Nestin regulates proliferation, migration, invasion and stemness of lung adenocarcinoma

(2014) KOSUKE NARITA et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Trimethylation of Histone H3 Lysine 36 by Human Methyltransferase PRDM9 Protein

(2014) Mohammad S. Eram et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nestin regulates prostate cancer cell invasion by influencing the localisation and functions of FAK and integrins

(2014) Claire L. Hyder et al.   JOURNAL OF CELL SCIENCE

Cancer stem cell detection and isolation

(2014) Meysam Moghbeli et al.   MEDICAL ONCOLOGY

The role of cancer stem cells in glioblastoma

(2014) Swetha J. Sundar et al.   Neurosurgical Focus

Melatonin Inhibits the Migration of Human Lung Adenocarcinoma A549 Cell Lines Involving JNK/MAPK Pathway

(2014) Qiaoyun Zhou et al.   PLoS One

Interplay between nuclear transport and ubiquitin/SUMO modifications in the regulation of cancer-related proteins

(2014) Jose A. Rodríguez   SEMINARS IN CANCER BIOLOGY

Histone modifications: Targeting head and neck cancer stem cells

(2014) John Le   World Journal of Stem Cells

Melatonin Suppresses the Expression of 45S Preribosomal RNA and Upstream Binding Factor and Enhances the Antitumor Activity of Puromycin in MDA-MB-231 Breast Cancer Cells

(2013) Ji Hoon Jung et al.   Evidence-based Complementary and Alternative Medicine

Melatonin antagonizes hypoxia-mediated glioblastoma cell migration and invasion via inhibition of HIF-1α

(2013) Yanmin Zhang et al.   JOURNAL OF PINEAL RESEARCH

Oncogenic Isocitrate Dehydrogenase Mutations: Mechanisms, Models, and Clinical Opportunities

(2013) R. A. Cairns et al.   Cancer Discovery

Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method

(2010) T.-C. Chou   CANCER RESEARCH

SUMOylation Mediates the Nuclear Translocation and Signaling of the IGF-1 Receptor

(2010) B. Sehat et al.   Science Signaling

Ginkgolic Acid Inhibits Protein SUMOylation by Blocking Formation of the E1-SUMO Intermediate

(2009) Isao Fukuda et al.   CHEMISTRY & BIOLOGY

Melatonin induces apoptotic death in LNCaP cells via p38 and JNK pathways: therapeutic implications for prostate cancer

(2009) Seong Soo Joo et al.   JOURNAL OF PINEAL RESEARCH

Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1α

(2009) A Soeda et al.   ONCOGENE

Neurogenic Potential of Isolated Precursor Cells from Early Post-Gastrula Somitic Tissue

(2009) Vincent Tropepe et al.   STEM CELLS AND DEVELOPMENT

Why Myc? An Unexpected Ingredient in the Stem Cell Cocktail

(2008) Paul S. Knoepfler   Cell Stem Cell

Nestin is expressed in basal-like and triple negative breast cancers

(2008) S Parry et al.   JOURNAL OF CLINICAL PATHOLOGY

c-Myc Is Required for Maintenance of Glioma Cancer Stem Cells

(2008) Jialiang Wang et al.   PLoS One