Prophylactic supplement with melatonin successfully suppresses the pathogenesis of periodontitis through normalizing RANKL/OPG ratio and depressing the TLR4/MyD88 signaling pathway
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Prophylactic supplement with melatonin successfully suppresses the pathogenesis of periodontitis through normalizing RANKL/OPG ratio and depressing the TLR4/MyD88 signaling pathway
Authors
Keywords
-
Journal
JOURNAL OF PINEAL RESEARCH
Volume 64, Issue 3, Pages e12464
Publisher
Wiley
Online
2017-12-24
DOI
10.1111/jpi.12464
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Administration of Exogenous Melatonin After the Onset of Systemic Inflammation Is Hardly Beneficial
- (2017) Lisa Brencher et al. INFLAMMATION
- Regulation of bone mass through pineal-derived melatonin-MT2 receptor pathway
- (2017) Kunal Sharan et al. JOURNAL OF PINEAL RESEARCH
- Melatonin successfully rescues hippocampal bioenergetics and improves cognitive function following drug intoxication by promoting Nrf2-ARE signaling activity
- (2017) Li-You Chen et al. JOURNAL OF PINEAL RESEARCH
- The acute exposure of tetrachloro- p -benzoquinone (a.k.a. chloranil) triggers inflammation and neurological dysfunction via Toll-like receptor 4 signaling: The protective role of melatonin preconditioning
- (2017) Juanli Fu et al. TOXICOLOGY
- RANK/RANKL/OPG Signalization Implication in Periodontitis: New Evidence from a RANK Transgenic Mouse Model
- (2017) Bouchra Sojod et al. Frontiers in Physiology
- Antioxidant effects of melatonin in heart tissue after induction of experimental periodontitis in rats
- (2017) Muhsin Özdem et al. Journal of Oral Science
- The Effect of Melatonin on Bone Loss, Diabetic Control, and Apoptosis in Rats With Diabetes With Ligature-Induced Periodontitis
- (2016) Hatice Balci Yuce et al. JOURNAL OF PERIODONTOLOGY
- Apoptosis signaling pathways in osteoarthritis and possible protective role of melatonin
- (2016) Azam Hosseinzadeh et al. JOURNAL OF PINEAL RESEARCH
- Melatonin as an antioxidant: under promises but over delivers
- (2016) Russel J. Reiter et al. JOURNAL OF PINEAL RESEARCH
- Therapeutic potential of melatonin in oral medicine and periodontology
- (2016) Shariq Najeeb et al. KAOHSIUNG JOURNAL OF MEDICAL SCIENCES
- Melatonin Suppresses Toll Like Receptor 4-Dependent Caspase-3 Signaling Activation Coupled with Reduced Production of Proinflammatory Mediators in Hypoxic Microglia
- (2016) Linli Yao et al. PLoS One
- Reduced dental calcium expression and dental mass in chronic sleep deprived rats: Combined EDS, TOF-SIMS, and micro-CT analysis
- (2015) Yi-Jie Kuo et al. APPLIED SURFACE SCIENCE
- Melatonin attenuates the TLR4-mediated inflammatory response through MyD88- and TRIF-dependent signaling pathways in an in vivo model of ovarian cancer
- (2015) Luiz Gustavo A Chuffa et al. BMC CANCER
- Effects of Melatonin on Morphological and Functional Parameters of the Pineal Gland and Organs of Immune System in Rats During Natural Light Cycle and Constant Illumination
- (2015) G. I. Litvinenko et al. BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
- Protective effects of melatonin on lipopolysaccharide-induced mastitis in mice
- (2015) Guoxi Shao et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Early-life sleep deprivation persistently depresses melatonin production and bio-energetics of the pineal gland: potential implications for the development of metabolic deficiency
- (2014) Li-You Chen et al. Brain Structure & Function
- Melatonin in the oral cavity: physiological and pathological implications
- (2014) R. J. Reiter et al. JOURNAL OF PERIODONTAL RESEARCH
- Melatonin feedback on clock genes: a theory involving the proteasome
- (2014) Jerry Vriend et al. JOURNAL OF PINEAL RESEARCH
- Protective effects of melatonin in reducing oxidative stress and in preserving the fluidity of biological membranes: a review
- (2014) Joaquín J. García et al. JOURNAL OF PINEAL RESEARCH
- Cytokine-Mediated Bone Destruction in Rheumatoid Arthritis
- (2014) Seung Min Jung et al. Journal of Immunology Research
- Melatonin Effects on Hard Tissues: Bone and Tooth
- (2013) Jie Liu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Multi-organ injuries caused by lipopolysaccharide-induced periodontal inflammation in rats: role of melatonin
- (2013) K. Gulle et al. JOURNAL OF PERIODONTAL RESEARCH
- Melatonin effects on bone: potential use for the prevention and treatment for osteopenia, osteoporosis, and periodontal disease and for use in bone-grafting procedures
- (2013) Sifat Maria et al. JOURNAL OF PINEAL RESEARCH
- Role of the Toll Like Receptor (TLR) Radical Cycle in Chronic Inflammation: Possible Treatments Targeting the TLR4 Pathway
- (2013) Kurt Lucas et al. MOLECULAR NEUROBIOLOGY
- MyD88 is essential for alveolar bone loss induced byAggregatibacter actinomycetemcomitanslipopolysaccharide in mice
- (2013) M.F.M. Madeira et al. Molecular Oral Microbiology
- Strain-dependent effects of long-term treatment with melatonin on kainic acid-induced status epilepticus, oxidative stress and the expression of heat shock proteins
- (2013) Milena Atanasova et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Immunomicrobial pathogenesis of periodontitis: keystones, pathobionts, and host response
- (2013) George Hajishengallis TRENDS IN IMMUNOLOGY
- Melatonin promotes angiogenesis during repair of bone defects: a radiological and histomorphometric study in rabbit tibiae
- (2012) María Piedad Ramírez-Fernández et al. Clinical Oral Investigations
- Preventive effects of trehalose on osteoclast differentiation in rat periodontitis model
- (2012) Yasumasa Endo et al. JOURNAL OF CLINICAL PERIODONTOLOGY
- Sustained release of melatonin from poly (lactic-co-glycolic acid) (PLGA) microspheres to induce osteogenesis of human mesenchymal stem cells in vitro
- (2012) Liangming Zhang et al. JOURNAL OF PINEAL RESEARCH
- A review of the molecular aspects of melatonin’s anti-inflammatory actions: recent insights and new perspectives
- (2012) José L. Mauriz et al. JOURNAL OF PINEAL RESEARCH
- Melatonin protects liver against ischemia and reperfusion injury through inhibition of toll-like receptor signaling pathway
- (2011) Jung-Woo Kang et al. JOURNAL OF PINEAL RESEARCH
- Toll-like receptors and their dual role in periodontitis: a review
- (2011) Mayank Hans et al. Journal of Oral Science
- Pro-inflammatory cytokine levels in association between periodontal disease and hyperlipidaemia
- (2010) Özlem Fentoğlu et al. JOURNAL OF CLINICAL PERIODONTOLOGY
- Destructive and Protective Roles of Cytokines in Periodontitis: A Re-appraisal from Host Defense and Tissue Destruction Viewpoints
- (2010) G.P. Garlet JOURNAL OF DENTAL RESEARCH
- Determination of the minimal melatonin exposure required to induce osteoblast differentiation from human mesenchymal stem cells and these effects on downstream signaling pathways
- (2010) Shalini Sethi et al. JOURNAL OF PINEAL RESEARCH
- Melatonin plus porcine bone on discrete calcium deposit implant surface stimulates osteointegration in dental implants
- (2009) José Luis Calvo-Guirado et al. JOURNAL OF PINEAL RESEARCH
- Angiogenesis in newly augmented bone observed in rabbit calvarium using a titanium cap
- (2008) Yutaka Yamada et al. CLINICAL ORAL IMPLANTS RESEARCH
- Dose translation from animal to human studies revisited
- (2007) Shannon Reagan-Shaw et al. FASEB JOURNAL
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started