Hydrogen deuterium exchange reveals changes to protein dynamics of recombinant human erythropoietin upon N- and O- desialylation

标题
Hydrogen deuterium exchange reveals changes to protein dynamics of recombinant human erythropoietin upon N- and O- desialylation
作者
关键词
Hydrogen deuterium exchange, EPO, Sialylation, Conformational change, Glycoprotein therapeutics
出版物
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
Volume 154, Issue -, Pages 454-459
出版商
Elsevier BV
发表日期
2018-03-17
DOI
10.1016/j.jpba.2018.02.060

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