Article
Biochemistry & Molecular Biology
Agnieszka Hanaka, Slawomir Dresler, Wieslaw Mulenko, Magdalena Wojciak, Ireneusz Sowa, Magdalena Sawic, Katarzyna Stanislawek, Maciej Strzemski
Summary: This study investigated the impact of the herbivore Cameraria ohridella and the pathogen Erysiphe flexuosa on secondary metabolite accumulation in chestnut leaves. The results showed that the accumulation of metabolites depended on the degree of pest infection, indicating the development of a metabolic response mechanism in chestnut trees to biological stress.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Physical
Matteo Ciardi, Federica Ianni, Roccaldo Sardella, Stefano Di Bona, Lina Cossignani, Raimondo Germani, Matteo Tiecco, Catia Clementi
Summary: Deep Eutectic Solvents (DESs) are attracting increasing attention as substitutes for polluting organic solvents due to their low or absent toxicity and volatility. They can be synthesized with natural bioavailable and biodegradable molecules, and are successfully used for extracting biofunctional molecules from plant matrices. Dilution of acid-based DESs with water has shown to be efficient for extracting molecules like quercetin from onion skin.
Article
Biochemistry & Molecular Biology
Vanessa B. Paula, Leticia M. Estevinho, Susana M. Cardoso, Luis G. Dias
Summary: Propolis, a natural product produced by bees, contains a complex mixture of compounds that contribute to its biological activities, such as antioxidant capacity. This study analyzed the pollen profile, phenolic compound content, antioxidant properties, and phenolic compound profile of four propolis samples from Portugal. Different techniques were used to determine total phenolic content and antioxidant capacity, and the presence of specific compounds in propolis samples significantly impacted their antioxidant capacity and quantification of total phenolic content. The major compounds identified in the propolis samples were chrysin, caffeic acid isoprenyl ester, pinocembrin, galangin, pinobanksin-3-O-acetate, and caffeic acid phenyl ester. The study highlights the importance of method selection for determining phenolic content and antioxidant activity in propolis samples and the contribution of specific compounds to their quantification.
Article
Engineering, Chemical
Chung-Chuan Hsueh, Timothy Jen Roxas, Yu-Hsuan Chan, Ching-Ning Juan, Lemmuel Lara Tayo, Ya-Yun Chen, Yun-Chen Wu, Kuo-Fen Hua, Po-Wei Tsai, Shu-Yun Sun, Bor-Yann Chen
Summary: This study quantitatively analyzed the optimal operational strategy for quercetin production from agricultural waste (onion peels) for the first time. Material recycling and reuse were achieved through fermentation and lactobacillus methods, demonstrating significant technical feasibility.
JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS
(2023)
Article
Food Science & Technology
Estefania J. Carrera, Maria Jesus Cejudo-Bastante, Nelson Hurtado, Francisco J. Heredia, M. Lourdes Gonzalez-Miret
Summary: Colombian purple corn Zea mays L. by-products were chemically characterized after purification and fractionation. Cob and leaves showed a more complete flavonoid profile with higher content of anthocyanins and flavonols compared to grains, resulting in the highest reducing power and radical scavenging activity. The antioxidant fractions corresponded to higher molecular weight compounds. This study provides the first chemical and antioxidant characterization of purple corn by-products, as well as pure fractions of Zea mays L. for various industries.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Food Science & Technology
Natalia Solarte, Maria Jesus Cejudo-Bastante, Nelson Hurtado, Francisco J. Heredia
Summary: A purification and fractionation process of the edible flowers of Tibouchina mollis and Tibouchina urvilleana was developed, followed by the identification and characterization of their anthocyanin and flavonol compounds using UHPLC-DAD-ESI-MS. The results showed that T. urvilleana had a higher monomeric anthocyanin content, while T. mollis exhibited a more diverse anthocyanin and flavonol profile. The purification process also resulted in an increase in antioxidant activity, which is closely related to reduction capacity.
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Food Science & Technology
Deniz Gunal-Koroglu, Hilal Yilmaz, Semra Turan, Esra Capanoglu
Summary: This paper investigated the fluorescence quenching effect of two phenolic extracts (red and yellow onion skin) on lentil protein isolate (LPI), and analyzed their thermodynamic parameters. The study found that the red onion skin extract had a more effective quenching effect at lower concentrations, while the yellow onion skin extract caused a blue shift at higher concentrations.
Article
Food Science & Technology
Rajender Kumar, Dinesh Kumar
Summary: Allium is widely consumed as a spice around the world. This study compared the metabolome and antioxidant activity of different tissues of Allium cepa, A. sativum, and A. semenovii. The results showed that A. cepa and A. semenovii had higher antioxidant activity and polyphenol content compared to A. sativum. Additionally, various metabolites including polyphenols and sulfur containing compounds were identified. This study highlights the potential of A. semenovii for utilization in food and nutraceuticals.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Biotechnology & Applied Microbiology
O. Benito-Roman, B. Blanco, M. T. Sanz, S. Beltran
Summary: The study demonstrated that Ultrasound Assisted Extraction (UAE) can effectively enhance the intensity and efficiency of flavonoid extraction from dry onion skin wastes. Compared to conventional stirred tank extraction, UAE significantly increases the productivity, extraction rate, and flavonoid content, providing a new approach for flavonoid extraction.
FOOD AND BIOPRODUCTS PROCESSING
(2021)
Article
Food Science & Technology
Sari Ramo, Minna Haapalainen, Satu Latvala
Summary: A method using MRM UHPLC-MS/MS was developed and successfully applied for quantifying Fusarium mycotoxins in harvested onions. The study focused on FB1, FB2, FB3, BEA, and MON, with good linearity and recovery rates obtained. The method allowed for accurate analysis of mycotoxins in infected onion samples, showing potential for future applications in monitoring and managing Fusarium basal rot in onion crops.
FOOD ANALYTICAL METHODS
(2021)
Article
Food Science & Technology
Dusica P. Ilic, Dragan Z. Troter, Ljiljana P. Stanojevic, Jelena B. Zvezdanovic, Danica D. Vukotic, Vesna D. Nikolic
Summary: This study conducted screening of bioactive components and antibacterial, antioxidant activity testing of Serbian cranberry juice using the UHPLC-DADMS/MS method. The results showed that cold-pressed juice exhibited higher antibacterial activity against Gram-positive bacteria.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Chemistry, Analytical
Noha F. El Azab
Summary: In this study, a LC-MS/MS approach was developed to detect and quantify certain COVID-19 candidate drugs in rat plasma. The method was validated according to US FDA criteria and showed satisfactory recoveries, low detection limits, and good precision and accuracy.
MICROCHEMICAL JOURNAL
(2022)
Article
Agricultural Engineering
Umair Khurshid, Saeed Ahmad, Hammad Saleem, Marya Aziz, Muhammad Asif Wazir, Muhammad Sarfraz, Sirajudheen Anwar, Siddique Akber Ansari, Sarfaraz Ahmed, Adriano Mollica, Mohamad Fawzi Mahomoodally, Nafees Ahemad
Summary: This research explores the phytochemical and biological properties of different polarity solvent extracts of Trianthema triquetra. The methanol extract shows the highest total phenolic and flavonoid content, as well as higher antioxidant capacity. The ethyl-acetate fraction exhibits strong inhibition against certain key enzymes, while the n-butanol and n-hexane extracts show activity against others. PCA analysis confirms the close association between bioactive contents and antioxidant assays.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Chemistry, Applied
Yan Zou, Yi Qian, Xiaoyun Rong, Kaixin Cao, David Julian McClements, Kun Hu
Summary: Composite nanoparticles with a caseinate/kappa-carrageenan coating were successfully prepared to encapsulate and deliver quercetin effectively. The quercetin-loaded nanoparticles showed stability and controlled release properties under various conditions, leading to increased bioaccessibility and antioxidant activities. These findings suggest the potential application of composite nanoparticles in dietary supplements, functional foods, and pharmaceutical products.
FOOD HYDROCOLLOIDS
(2021)
Article
Chemistry, Analytical
Nikunj Tanna, Robert S. Plumb, Billy J. Molloy, Paul D. Rainville, Ian D. Wilson
Summary: The use of vacuum jacketed LC columns (VJC) is evaluated as a potential approach to improve high throughput (HT) analysis. In this study, the VJC method is applied to the bioanalysis of the antidiabetic drug fasiglifam in rat plasma samples. The results show significant improvements in chromatographic performance and separation of the drug from matrix interferences compared to conventional methods. The use of VJC/MS with a rapid 1 min analysis provides a reduction in peak width, higher peak response, and doubled analytical throughput compared to UHPLC/MS method.
Correction
Chemistry, Applied
Katarzyna Grzelak-Blaszczyk, Andrzej Czarnecki, Robert Klewicki, Maria Grzegorzewska, Elzbieta Klewicka
Summary: The authors apologize for an incorrect affiliation of one of the authors in the article, and provide the correct affiliation information. They apologize for any inconvenience caused.
Article
Biochemistry & Molecular Biology
Bartosz Fotschki, Katarzyna Ognik, Joanna Fotschki, Dorota Napiorkowska, Ewelina Cholewinska, Magdalena Krauze, Jerzy Juskiewicz
Summary: The study investigated the effects of chromium supplementation and switching dietary habits on lipid metabolism, inflammation, and oxidative stress in Wistar rats. The combination of chromium nanoparticles and dietary changes showed the strongest reduction in fat content and cholesterol in the liver. This combination also had favorable antioxidative effects. Supplementation with chromium nanoparticles alone also improved lipid metabolism and oxidative stress, although to a lesser extent.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Nutrition & Dietetics
Bartosz Fotschki, Ewelina Cholewinska, Katarzyna Ognik, Michal Sojka, Joanna Milala, Joanna Fotschki, Wieslaw Wiczkowski, Jerzy Juskiewicz
Summary: The required amount of berry polyphenols for health benefits is difficult to achieve through fresh fruit consumption, suggesting polyphenol-rich extracts as a dietary alternative. This study fed rats high-fat diets supplemented with 0.1 or 0.3% raspberry polyphenols and found that the higher dose of extract had more noticeable health-promoting effects, including reduced white adipose tissue weight, hepatic triglyceride content, and plasma IL-6 concentration, as well as increased acetic acid concentration in the cecal digesta. The enhanced content of ellagitannin and anthocyanin metabolites in the blood plasma of rats administered the high dose extract may partially explain these effects.
Article
Food Science & Technology
Agnieszka Hejduk, Michal Sojka, Robert Klewicki
Summary: The aim of this study was to determine the stability of ellagitannins, ellagic acid, and conjugates in unclarified juices and purees made from two selected berries of the Rosaceae family, genus Fragaria. A total of 16 ellagitannins were identified in the products. Stability studies were conducted for 1 year at three different temperatures: -20, 4, and 20 degrees C (+/- 2 degrees C). The stability of the compounds was influenced by temperature, storage time, and the matrix.
FOOD SCIENCE & NUTRITION
(2023)
Review
Biochemistry & Molecular Biology
Joanna Fotschki, Anna M. M. Ogrodowczyk, Barbara Wroblewska, Jerzy Juskiewicz
Summary: The vegetable processing industry generates large amounts of by-products that are susceptible to microbial degradation. Inadequate management leads to the loss of valuable compounds in vegetable by-products. Scientists are exploring the possibility of reusing discarded biomass to create higher value products. The by-products contain bioactive compounds with health-promoting properties. This review emphasizes the importance of these by-products in promoting health through their impact on the microbiota, immune system, and gut milieu.
Article
Nutrition & Dietetics
Ewelina Cholewinska, Aleksandra Marzec, Przemyslaw Solek, Bartosz Fotschki, Piotr Listos, Katarzyna Ognik, Jerzy Juskiewicz
Summary: The aim of this study was to investigate the effects of different types of dietary fibre (cellulose, inulin, pectin, and psyllium) in combination with recommended or enhanced levels of CuNPs on selected biological parameters of intestinal integrity in rats. The results showed that replacing CuCO3 with CuNPs in the diet reduced lactic acid and apoptosis markers levels in the small intestine, but it also increased DNA oxidation. Inulin had the most beneficial effect on DNA repair mechanisms, while pectin had the highest ability to inhibit inflammatory processes and apoptotic cell death in the small intestine. These findings suggest that dietary fibre supplementation can protect the small intestine against oxidative effects of CuNPs by enhancing the intestinal barrier.
Article
Biochemistry & Molecular Biology
Monika Cendrowska-Pinkosz, Magdalena Krauze, Jerzy Juskiewicz, Bartosz Fotschki, Katarzyna Ognik
Summary: The aim of this study is to evaluate the effect of different forms and dosages of copper on neurodegenerative markers in the brain and jejunum. The experiment involved feeding male Wistar rats a rat diet with two CuCO3 dosages and two CuNP dosages. Nanoparticles reduced the level of GAChE, increased the levels of AChE and LRP1, and decreased β-amyloid and Tau protein in both the brain and intestine of rats. The highest levels of beneficial markers and lowest levels of toxic markers were observed in rats receiving a standard dose of Cu.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Nutrition & Dietetics
Michal Majewski, Leszek Gromadzinski, Ewelina Cholewinska, Katarzyna Ognik, Bartosz Fotschki, Jerzy Juskiewicz
Summary: This study aimed to investigate the effects of dietary fiber supplementation with different types of nanoparticles on the cardiovascular system in rats. The results showed that compared to pectin, inulin and psyllium supplementation with a standard dose of copper nanoparticles improved antioxidant capacity and reduced heart malondialdehyde levels. Furthermore, with an enhanced dose of copper nanoparticles, inulin and psyllium enhanced vasodilation through up-regulation of COX-2-derived vasodilator prostanoids.
Article
Nutrition & Dietetics
Bartosz Fotschki, Michal Sojka, Monika Kosmala, Jerzy Juskiewicz
Summary: Previous studies have shown that dietary supplementation with prebiotic fructooligosaccharides (FOSs) and polyphenols can alleviate disorders related to the early stage of nonalcoholic fatty liver disease (NAFLD). This experiment aimed to investigate whether raspberry polyphenols together with FOSs can regulate advanced-stage NAFLD in genetically obese Zucker rats. The results showed that the addition of FOSs and raspberry polyphenolic extract to the diet reduced liver fat accumulation, improved antioxidant potential, lowered plasma enzyme activities, and increased insulin sensitivity. These effects may be attributed to the upregulation of specific receptors in the liver responsible for regulating lipid metabolism and glucose and bile acid synthesis.
Article
Nutrition & Dietetics
Bartosz Fotschki, Katarzyna Ognik, Ewelina Cholewinska, Katarzyna Grzelak-Blaszczyk, Kamil Myszczynski, Magdalena Krauze, Jerzy Juskiewicz
Summary: This study aimed to investigate the effects of supplementation with chromium nanoparticles (Cr-NPs) on the gut microenvironment in rats fed a high-fat diet. The results showed that Cr-NPs mainly acted by altering the activity of gut microbiota, leading to decreased concentration of short-chain fatty acids and increased level of cecal lithocholic acid. Switching to a low-fat diet had a more significant impact on obesity-related disorders, improving microbial activity, composition, and the production of short-chain fatty acids.
Article
Agriculture, Dairy & Animal Science
Janusz Strychalski, Dorota Kowalska, Slawomir Grinholc, Jerzy Juskiewicz, Bartosz Fotschki, Andrzej Gugolek
Summary: The study found that dietary supplementation with black cumin seed meal had no significant impact on the growth performance of rabbits but reduced coccidia oocyst counts in adult rabbit feces. It also decreased the presence of putrefactive compounds and intestinal viscosity, as well as increased liver weight and plasma albumin levels.
ANNALS OF ANIMAL SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Xinyu Wang, Jun Huang, Huan Li, Yanlong Li, Shuang Cai, Bangxin Xue, Zhekun Zhu, Xiangzhou Zeng, Xiangfang Zeng
Summary: Embryo development plays a crucial role in pregnancy outcome and lifelong health. A high throughput screening cell model was established to select nutrients that can enhance embryonic development. Resveratrol was identified as a potential candidate for promoting embryo development.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Ren Yoshitomi, Motofumi Kumazoe, Kwan-Woo Lee, Yuki Marugame, Yoshinori Fujimura, Hirofumi Tachibana
Summary: This study investigated the connection between food components and circular RNA (circRNA), as well as the regulatory effect of (-)-Epigallocatechin-3-O-gallate (EGCG) on circRNA expression in the liver. The results showed that EGCG treatment altered the expression of circRNAs in mice livers, and one upregulated circRNA (mmu_circRNA_011775) affected the expression of genes related to liver fibrosis and the cardiovascular system.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
ViVi Tang Kang Wee, Hitoshi Shirakawa, Sung-Ling Yeh, Chiu-Li Yeh
Summary: This study investigated the effects of fermented rice bran (FRB) on modulating intestinal aryl hydrocarbon receptor (AhR) expression, innate lymphoid cell (ILC)3 populations, the fecal microbiota distribution, and their associations with dextran sodium sulfate (DSS)-induced acute colitis. The results showed that FRB supplementation can improve gut health, alleviate colitis symptoms, and have anti-colitis effects by enhancing ILC3 and AhR functions.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Xinzhuang Ma, Xijuan Ren, Xuemin Zhang, Guangyin Wang, Hui Liu, Li Wang
Summary: The study demonstrates that rutin can ameliorate kidney damage caused by PFOA exposure by improving oxidative stress and regulating lipid metabolism.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Ya-Jie Ding, Xue-Ning Li, Zhe Xiao, Chen-Yang Li, Li-Hong Jia
Summary: This study investigates the impact of maternal vitamin D levels during pregnancy on infantile eczema. The findings suggest that lower prenatal maternal vitamin D levels increase the risk of eczema in infants aged 0-1 year. Furthermore, the study indicates that infants with eczema have lower expression of the Foxp3 gene in cord blood and decreased placental FOXP3 protein expression. These results suggest that vitamin D may affect the development of infantile eczema through the regulation of gene and protein expression in cord blood and placenta.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Shujing Liu, Shiyu Song, Shuan Wang, Tonghui Cai, Lian Qin, Xinzhuang Wang, Guangming Zhu, Haibo Wang, Wenqi Yang, Chunlu Fang, Yuan Wei, Fu Zhou, Yang Yu, Shaozhang Lin, Shuang Peng, Liangming Li
Summary: Long-term consumption of a high-fat diet disrupts energy balance and leads to weight gain. The fat mass and obesity-associated (FTO) gene is involved in high-fat diet-induced obesity. The hypothalamus plays a crucial role in regulating energy balance, and high-fat diet-induced hypothalamic leptin resistance contributes to obesity. The study reveals that FTO is associated with hypothalamic leptin resistance and provides new insight into its role in obesity.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Shuang Liu, Xiaoling Chen, Jun He, Yuheng Luo, Ping Zheng, Bing Yu, Daiwen Chen, Zhiqing Huang
Summary: This study found that oleanolic acid promotes the transformation of fast muscle fibers to slow muscle fibers through the TGR5-mediated CaN/NFATc1 signaling pathway.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Huijuan Hu, Fan Li, Shaoli Cheng, Tingting Qu, Fanqi Shen, Jie Cheng, Lina Chen, Zhenghang Zhao, Hao Hu
Summary: Long-term alternate-day fasting can ameliorate obesity-induced anxiety-like behavior and hippocampal damage, but it can cause anxiety in normal-weight mice. Short-term alternate-day fasting does not produce adverse emotional reactions in normal-weight mice.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Jannis Ulke, Christian Schwedler, Janine Krueger, Vanessa Stein, Peter Geserick, Andre Kleinridders, Kai Kappert
Summary: This study characterized the glycosylation pattern of PTPRJ in the liver and found that high-fat diet-induced obesity altered the glycosylation pattern of PTPRJ. These findings provide new insights into the role of glycosylation in metabolic disorders.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Shuang Liu, Marii Mochizuki, Yasuyuki Suzuki, Erika Takemasa, Akiko Yano, Matome Imai, Masaki Mogi
Summary: This study evaluated the feasibility and efficacy of leucine supplementation in offsetting immune dysfunction in sarcopenia. The results showed that leucine supplementation not only improved muscle mass and restored mitochondrial respiratory function, but also reduced inflammation levels. These findings are important for the rational design and optimization of leucine supplementation in patients with sarcopenia and autoimmune diseases.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2024)
Review
Biochemistry & Molecular Biology
Zhan Su, Jun Fang, Bin Yao, Gang Liu
Summary: Osteoporosis is a serious skeletal disorder that can be prevented and treated by polyphenols, which have antioxidant and anti-allergy properties. Polyphenols affect bone metabolism and density by inhibiting oxidative stress and exhibiting antibacterial effects. This article provides an overview of the preventive and therapeutic effects of polyphenols on osteoporosis and discusses the mechanisms involved.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Qian Zhang, Xinhua Xiao, Jia Zheng, Ming Li, Miao Yu, Fan Ping, Tong Wang, Xiaojing Wang
Summary: Maternal high-fat diet can affect the structure and function of offspring's pancreas, leading to weight gain, glucose metabolism disorders, and insulin secretion defects. The study found that this may be related to DNA methylation of specific genes in the pancreas.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Hanaa Mousa, Aisha Al Saei, Rozaimi Mohamad Razali, Susu M. Zughaier
Summary: Vitamin D deficiency and dyslipidemia have significant implications for human health. This study investigates the proteomic profiles of individuals with and without these conditions, revealing decreased HDL-associated apolipoproteins and increased acute-phase proteins. Pathway analysis highlights inflammatory and cancer pathways associated with vitamin D deficiency and dyslipidemia.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Qi-Lan Jiang, Tao Li, Qin Xu, Yang Zeng, Wei Wang, Bo-Tao Zhang, Qing-Ping Yao, Rui Jiang, Jun Jiang
Summary: Environmental factors, especially dietary habits, play a significant role in the susceptibility and progression of cardiovascular diseases through epigenetic modification. This study found that a methyl donor diet can attenuate balloon injury-induced intimal hyperplasia in rat carotid arteries, potentially by influencing the composition and function of the extracellular matrix.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2024)
Review
Biochemistry & Molecular Biology
Jiayi Cai, Yajie Qiao, Lingbin Chen, Youguang Lu, Dali Zheng
Summary: The Notch signaling pathway plays a regulatory role in normal biological processes such as cellular differentiation, apoptosis, and stem cell self-renewal. Dysregulation of this pathway is associated with various types of cancer. Natural products targeting the Notch pathway have shown potential as chemopreventive and anti-cancer agents, providing a feasible solution to fight against cancer by either alone or in combination with current therapeutic agents.
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2024)