Dual modulation on glial cells by tetrahydroxystilbene glucoside protects against dopamine neuronal loss

Histamine upregulates the expression of histamine receptors and increases the neuroprotective effect of astrocytes

(2018) Jiawen Xu et al.   Journal of Neuroinflammation

LncRNA H19 contributes to hippocampal glial cell activation via JAK/STAT signaling in a rat model of temporal lobe epilepsy

(2018) Chun-Lei Han et al.   Journal of Neuroinflammation

Caffeine and Modafinil Ameliorate the Neuroinflammation and Anxious Behavior in Rats during Sleep Deprivation by Inhibiting the Microglia Activation

(2018) Meetu Wadhwa et al.   Frontiers in Cellular Neuroscience

Butein provides neuroprotective and anti-neuroinflammatory effects through Nrf2/ARE-dependent haem oxygenase 1 expression by activating the PI3K/Akt pathway

(2016) Dong-Sung Lee et al.   BRITISH JOURNAL OF PHARMACOLOGY

Tetrahydroxystilbene Glucoside Improves Neurotrophic Factors Release in Cultured Astroglia

(2016) FengQin Lin et al.   CNS & Neurological Disorders-Drug Targets

Critical role of the Mac1/NOX2 pathway in mediating reactive microgliosis-generated chronic neuroinflammation and progressive neurodegeneration

(2016) Shih-Heng Chen et al.   CURRENT OPINION IN PHARMACOLOGY

Overexpression of HDAC6 induces pro-inflammatory responses by regulating ROS-MAPK-NF-κB/AP-1 signaling pathways in macrophages

(2016) Gi Soo Youn et al.   FREE RADICAL BIOLOGY AND MEDICINE

Rice bran derivatives alleviate microglia activation: possible involvement of MAPK pathway

(2016) Harsharan S. Bhatia et al.   Journal of Neuroinflammation

Anti-Inflammatory Modulation of Microglia via CD163-Targeted Glucocorticoids Protects Dopaminergic Neurons in the 6-OHDA Parkinson's Disease Model

(2016) Noemie Tentillier et al.   JOURNAL OF NEUROSCIENCE

Prothrombin Kringle-2: A Potential Inflammatory Pathogen in the Parkinsonian Dopaminergic System

(2016) Eunju Leem et al.   Experimental Neurobiology

Post-treatment with an ultra-low dose of NADPH oxidase inhibitor diphenyleneiodonium attenuates disease progression in multiple Parkinson’s disease models

(2015) Qingshan Wang et al.   BRAIN

Activating mitochondrial function and haemoglobin expression with EH-201, an inducer of erythropoietin in neuronal cells, reverses memory impairment

(2015) Lin-Yea Horng et al.   BRITISH JOURNAL OF PHARMACOLOGY

Sequential activation of microglia and astrocyte cytokine expression precedes increased iba-1 or GFAP immunoreactivity following systemic immune challenge

(2015) Diana M. Norden et al.   GLIA

Neuroinflammation in Parkinson's disease: role in neurodegeneration and tissue repair

(2015) Sayinthen Vivekanantham et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Loss of VGLUT3 Produces Circadian-Dependent Hyperdopaminergia and Ameliorates Motor Dysfunction and L-Dopa-Mediated Dyskinesias in a Model of Parkinson's Disease

(2015) C. B. Divito et al.   JOURNAL OF NEUROSCIENCE

BDNF parabrachio-amygdaloid pathway in morphine-induced analgesia

(2013) Maysa Sarhan et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

TSG (2,3,4’ ,5-tetrahydroxystilbene 2-O-β-D-glucoside) suppresses induction of pro-inflammatory factors by attenuating the binding activity of nuclear factor-κB in microglia

(2013) Chao Huang et al.   Journal of Neuroinflammation

Small-molecule modulation of neurotrophin receptors: a strategy for the treatment of neurological disease

(2013) Frank M. Longo et al.   NATURE REVIEWS DRUG DISCOVERY

Regulated Expression of Lentivirus-Mediated GDNF in Human Bone Marrow-Derived Mesenchymal Stem Cells and Its Neuroprotection on Dopaminergic Cells In Vitro

(2013) Wei-Hua Yang et al.   PLoS One

Targeting Astrocytes Ameliorates Neurologic Changes in a Mouse Model of Alzheimer's Disease

(2012) J. L. Furman et al.   JOURNAL OF NEUROSCIENCE

Activity-dependent, stress-responsive BDNF signaling and the quest for optimal brain health and resilience throughout the lifespan

(2012) S.M. Rothman et al.   NEUROSCIENCE

Regional Astrocyte Allocation Regulates CNS Synaptogenesis and Repair

(2012) H.-H. Tsai et al.   SCIENCE

Neurotrophic factors for the treatment of Parkinson's disease

(2011) Aideen M. Sullivan et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Neuroinflammation and α-Synuclein Dysfunction Potentiate Each Other, Driving Chronic Progression of Neurodegeneration in a Mouse Model of Parkinson’s Disease

(2011) Hui-Ming Gao et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

HMGB1 Acts on Microglia Mac1 to Mediate Chronic Neuroinflammation That Drives Progressive Neurodegeneration

(2011) H.-M. Gao et al.   JOURNAL OF NEUROSCIENCE

Beneficial Effects of THSG on Acetic Acid-Induced Experimental Colitis: Involvement of Upregulation of PPAR-γ and Inhibition of the Nf-Κb Inflammatory Pathway

(2011) Cheng Zeng et al.   MOLECULES

Self-amplifying autocrine actions of BDNF in axon development

(2011) P.-L. Cheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuroprotective effects of curcumin on 6-hydroxydopamine-induced Parkinsonism in rats: Behavioral, neurochemical and immunohistochemical studies

(2010) Gulrana Khuwaja et al.   BRAIN RESEARCH

Neurotrophic factors in Alzheimer’s disease: role of axonal transport

(2010) K. Schindowski et al.   GENES BRAIN AND BEHAVIOR

Inhibition of I B Kinase-  Protects Dopamine Neurons Against Lipopolysaccharide-Induced Neurotoxicity

(2010) F. Zhang et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Resveratrol Protects Dopamine Neurons Against Lipopolysaccharide-Induced Neurotoxicity through Its Anti-Inflammatory Actions

(2010) F. Zhang et al.   MOLECULAR PHARMACOLOGY

A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone

(2010) S.-W. Jang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protection by tetrahydroxystilbene glucoside against cerebral ischemia: involvement of JNK, SIRT1, and NF-κB pathways and inhibition of intracellular ROS/RNS generation

(2009) Ting Wang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Tetrahydroxy stilbene glucoside reduces the cognitive impairment and overexpression of amyloid precursor protein induced by aluminum exposure

(2009) Hong-Bo Luo et al.   Neuroscience Bulletin

PPARα ligands inhibit radiation-induced microglial inflammatory responses by negatively regulating NF-κB and AP-1 pathways

(2008) Sriram Ramanan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Why neurodegenerative diseases are progressive: uncontrolled inflammation drives disease progression

(2008) Hui-Ming Gao et al.   TRENDS IN IMMUNOLOGY