Central blockade of NLRP3 reduces blood pressure via regulating inflammation microenvironment and neurohormonal excitation in salt-induced prehypertensive rats

NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice

(2017) Auvro R. Mridha et al.   JOURNAL OF HEPATOLOGY

Anakinra reduces blood pressure and renal fibrosis in one kidney/DOCA/salt-induced hypertension

(2017) Yeong Hann Ling et al.   PHARMACOLOGICAL RESEARCH

A murine model of inflammation-induced cerebral microbleeds

(2016) Rachita K. Sumbria et al.   Journal of Neuroinflammation

Inflammasome activity is essential for one kidney/deoxycorticosterone acetate/salt-induced hypertension in mice

(2015) S M Krishnan et al.   BRITISH JOURNAL OF PHARMACOLOGY

Targeting Interleukin-1 beta to Suppress Sympathoexcitation in Hypothalamic Paraventricular Nucleus in Dahl Salt-Sensitive Hypertensive Rats

(2015) Jie Qi et al.   Cardiovascular Toxicology

Blockade of Salusin-β in Hypothalamic Paraventricular Nucleus Attenuates Hypertension and Cardiac Hypertrophy in Salt-induced Hypertensive Rats

(2015) Hong-Bao Li et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Toll-like receptor 4 inhibition within the paraventricular nucleus attenuates blood pressure and inflammatory response in a genetic model of hypertension

(2015) Rahul B Dange et al.   Journal of Neuroinflammation

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

(2015) Rebecca C Coll et al.   NATURE MEDICINE

Inhibition of NF-κB activity in the hypothalamic paraventricular nucleus attenuates hypertension and cardiac hypertrophy by modulating cytokines and attenuating oxidative stress

(2015) Xiao-Jing Yu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Arterial Hypertension Aggravates Innate Immune Responses after Experimental Stroke

(2015) Karoline Möller et al.   Frontiers in Cellular Neuroscience

Central blockade of salusin β attenuates hypertension and hypothalamic inflammation in spontaneously hypertensive rats

(2015) Hong-Bao Li et al.   Scientific Reports

Central blockade of TLR4 improves cardiac function and attenuates myocardial inflammation in angiotensin II-induced hypertension

(2014) Rahul B. Dange et al.   CARDIOVASCULAR RESEARCH

Chronic Cardiovascular Disease-Associated Gene Network Analysis in Human Umbilical Vein Endothelial Cells Exposed to 2,3,7,8-Tetrachlorodibenzo-p-dioxin

(2014) Yu Yu et al.   Cardiovascular Toxicology

Oleuropein Offers Cardioprotection in Rats with Acute Myocardial Infarction

(2014) Zeinab Janahmadi et al.   Cardiovascular Toxicology

The Autonomic Nervous System and Hypertension

(2014) Giuseppe Mancia et al.   CIRCULATION RESEARCH

Chronic variable stress activates hematopoietic stem cells

(2014) Timo Heidt et al.   NATURE MEDICINE

Exercise Training Attenuates Hypertension and Cardiac Hypertrophy by Modulating Neurotransmitters and Cytokines in Hypothalamic Paraventricular Nucleus

(2014) Lin-Lin Jia et al.   PLoS One

Inhibition of TNF-α in hypothalamic paraventricular nucleus attenuates hypertension and cardiac hypertrophy by inhibiting neurohormonal excitation in spontaneously hypertensive rats

(2014) Xin-Ai Song et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Chronic infusion of lisinopril into hypothalamic paraventricular nucleus modulates cytokines and attenuates oxidative stress in rostral ventrolateral medulla in hypertension

(2014) Hong-Bao Li et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Inhibition of reactive oxygen species in hypothalamic paraventricular nucleus attenuates the renin–angiotensin system and proinflammatory cytokines in hypertension

(2014) Qing Su et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Spontaneous white matter damage, cognitive decline and neuroinflammation in middle-aged hypertensive rats: an animal model of early-stage cerebral small vessel disease

(2014) Daniel Kaiser et al.   Acta Neuropathologica Communications

Immunosenescent CD8 + T Cells and C-X-C Chemokine Receptor Type 3 Chemokines Are Increased in Human Hypertension

(2013) Jong-Chan Youn et al.   HYPERTENSION

Linking endothelial dysfunction with endothelial cell activation

(2013) James K. Liao   JOURNAL OF CLINICAL INVESTIGATION

Chronic infusion of enalaprilat into hypothalamic paraventricular nucleus attenuates angiotensin II-induced hypertension and cardiac hypertrophy by restoring neurotransmitters and cytokines

(2013) Yu-Ming Kang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke

(2012) M. Gelderblom et al.   BLOOD

Neurohormonal Modulation of the Innate Immune System Is Proinflammatory in the Prehypertensive Spontaneously Hypertensive Rat, a Genetic Model of Essential Hypertension

(2012) Sailesh C. Harwani et al.   CIRCULATION RESEARCH

Paraventricular nucleus corticotrophin releasing hormone contributes to sympathoexcitation via interaction with neurotransmitters in heart failure

(2011) Yu-Ming Kang et al.   BASIC RESEARCH IN CARDIOLOGY

Angiotensin II–Induced Hypertension Is Modulated by Nuclear Factor-κB in the Paraventricular Nucleus

(2011) Jeffrey P. Cardinale et al.   HYPERTENSION

CXCL10/CXCR3 signaling in glia cells differentially affects NMDA-induced cell death in CA and DG neurons of the mouse hippocampus

(2010) Hilmar R.J. van Weering et al.   HIPPOCAMPUS

Inflammation, Immunity, and Hypertension

(2010) David G. Harrison et al.   HYPERTENSION

Heterogeneity of small vessel disease: a systematic review of MRI and histopathology correlations

(2010) A. A. Gouw et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Brain nuclear factor-kappa B activation contributes to neurohumoral excitation in angiotensin II-induced hypertension

(2009) Y.-M. Kang et al.   CARDIOVASCULAR RESEARCH

Brain tumour necrosis factor-  modulates neurotransmitters in hypothalamic paraventricular nucleus in heart failure

(2009) Y.-M. Kang et al.   CARDIOVASCULAR RESEARCH

Role of Proinflammatory Cytokines and Redox Homeostasis in Exercise-Induced Delayed Progression of Hypertension in Spontaneously Hypertensive Rats

(2009) Deepmala Agarwal et al.   HYPERTENSION

The NLRP3 inflammasome: A sensor of immune danger signals

(2009) Suzanne L. Cassel et al.   SEMINARS IN IMMUNOLOGY

Involvement of Tumor Necrosis Factor-α in Angiotensin II–Mediated Effects on Salt Appetite, Hypertension, and Cardiac Hypertrophy

(2008) Srinivas Sriramula et al.   HYPERTENSION

Unaltered Neurological Disease and Mortality in CXCR3-Deficient Mice Infected Intracranially with Lymphocytic Choriomeningitis Virus-Armstrong

(2008) Markus J. Hofer et al.   VIRAL IMMUNOLOGY