NADPH oxidases as potential pharmacological targets against increased seizure susceptibility after systemic inflammation

Modulation of neuronal excitability by immune mediators in epilepsy

(2016) Valentina Iori et al.   CURRENT OPINION IN PHARMACOLOGY

The Chemokine CCL2 Mediates the Seizure-enhancing Effects of Systemic Inflammation

(2016) Chiara Cerri et al.   JOURNAL OF NEUROSCIENCE

Post-treatment with an ultra-low dose of NADPH oxidase inhibitor diphenyleneiodonium attenuates disease progression in multiple Parkinson’s disease models

(2015) Qingshan Wang et al.   BRAIN

IL-6 regulation of synaptic function in the CNS

(2015) Donna L. Gruol   NEUROPHARMACOLOGY

Traumatic Brain Injury and NADPH Oxidase: A Deep Relationship

(2015) Cristina Angeloni et al.   Oxidative Medicine and Cellular Longevity

Epilepsy and innate immune system: A possible immunogenic predisposition and related therapeutic implications

(2015) Nassim Matin et al.   Human Vaccines & Immunotherapeutics

Peripheral inflammation is associated with remote global gene expression changes in the brain

(2014) Carolyn A Thomson et al.   Journal of Neuroinflammation

The role of Nox2-derived ROS in the development of cognitive impairment after sepsis

(2014) Marina S Hernandes et al.   Journal of Neuroinflammation

Natural Compounds as Modulators of NADPH Oxidases

(2013) Tullia Maraldi   Oxidative Medicine and Cellular Longevity

A Systematic Analysis of the Peripheral and CNS Effects of Systemic LPS, IL-1Β, TNF-α and IL-6 Challenges in C57BL/6 Mice

(2013) Donal T. Skelly et al.   PLoS One

Understanding brain dysfunction in sepsis

(2013) Romain Sonneville et al.   Annals of Intensive Care

Cytokine and chemokine responses in serum and brain after single and repeated injections of lipopolysaccharide: Multiplex quantification with path analysis

(2011) Michelle A. Erickson et al.   BRAIN BEHAVIOR AND IMMUNITY

Cytokines and brain excitability

(2011) Michael A. Galic et al.   FRONTIERS IN NEUROENDOCRINOLOGY

β2-Adrenergic Receptor Activation Prevents Rodent Dopaminergic Neurotoxicity by Inhibiting Microglia via a Novel Signaling Pathway

(2011) Li Qian et al.   JOURNAL OF IMMUNOLOGY

Microglia activation triggers astrocyte-mediated modulation of excitatory neurotransmission

(2011) O. Pascual et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cytokines and epilepsy

(2011) Gang Li et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Comparative pharmacology of chemically distinct NADPH oxidase inhibitors

(2010) S Wind et al.   BRITISH JOURNAL OF PHARMACOLOGY

Glia as a source of cytokines: Implications for neuronal excitability and survival

(2010) Annamaria Vezzani et al.   EPILEPSIA

Chemokine CCL2 modulation of neuronal excitability and synaptic transmission in rat hippocampal slices

(2010) Yan Zhou et al.   JOURNAL OF NEUROCHEMISTRY

Gp91phox (NOX2) in classically activated microglia exacerbates traumatic brain injury

(2010) Kenji Dohi et al.   Journal of Neuroinflammation

The role of inflammation in epilepsy

(2010) Annamaria Vezzani et al.   Nature Reviews Neurology

Microglial ablation and lipopolysaccharide preconditioning affects pilocarpine-induced seizures in mice

(2010) Martine M. Mirrione et al.   NEUROBIOLOGY OF DISEASE

The cortical innate immune response increases local neuronal excitability leading to seizures

(2009) K. M. Rodgers et al.   BRAIN

Contributions of peripheral inflammation to seizure susceptibility: Cytokines and brain excitability

(2009) Kiarash Riazi et al.   EPILEPSY RESEARCH

Nox proteins in signal transduction

(2009) David I. Brown et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cerebral Microglia Recruit Monocytes into the Brain in Response to Tumor Necrosis Factor  Signaling during Peripheral Organ Inflammation

(2009) C. D'Mello et al.   JOURNAL OF NEUROSCIENCE

Novel Neuroprotective Mechanisms of Memantine: Increase in Neurotrophic Factor Release from Astroglia and Anti-Inflammation by Preventing Microglial Activation

(2009) Hung-Ming Wu et al.   NEUROPSYCHOPHARMACOLOGY

Peripheral tumors induce depressive-like behaviors and cytokine production and alter hypothalamic-pituitary-adrenal axis regulation

(2009) L. M. Pyter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The incidence, aetiology and outcome of acute seizures in children admitted to a rural Kenyan district hospital

(2008) Richard Idro et al.   BMC Pediatrics

Neonatal inflammation produces selective behavioural deficits and alters N-methyl-d-aspartate receptor subunit mRNA in the adult rat brain

(2008) E.-M. Harré et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Genetic deficiency of NADPH oxidase does not diminish, but rather enhances, LPS-induced acute inflammatory responses in vivo

(2008) Wei-Jian Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Neurotoxic Activation of Microglia Is Promoted by a Nox1-Dependent NADPH Oxidase

(2008) C. Cheret et al.   JOURNAL OF NEUROSCIENCE

Postnatal Inflammation Increases Seizure Susceptibility in Adult Rats

(2008) M. A. Galic et al.   JOURNAL OF NEUROSCIENCE

Interleukin Converting Enzyme inhibition impairs kindling epileptogenesis in rats by blocking astrocytic IL-1β production

(2008) Teresa Ravizza et al.   NEUROBIOLOGY OF DISEASE

Microglial activation and TNF  production mediate altered CNS excitability following peripheral inflammation

(2008) K. Riazi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Why neurodegenerative diseases are progressive: uncontrolled inflammation drives disease progression

(2008) Hui-Ming Gao et al.   TRENDS IN IMMUNOLOGY