Hemopexin increases the neurotoxicity of hemoglobin when haptoglobin is absent

Neuronal Death After Hemorrhagic Stroke In Vitro and In Vivo Shares Features of Ferroptosis and Necroptosis

(2017) Marietta Zille et al.   STROKE

Increased brain hemopexin levels improve outcomes after intracerebral hemorrhage

(2016) Jenna L Leclerc et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Low-density lipoprotein receptor-related protein-1 facilitates heme scavenging after intracerebral hemorrhage in mice

(2016) Gaiqing Wang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Haptoglobin increases the vulnerability of CD163-expressing neurons to hemoglobin

(2016) Jing Chen-Roetling et al.   JOURNAL OF NEUROCHEMISTRY

Deletion of the hemopexin or heme oxygenase-2 gene aggravates brain injury following stroma-free hemoglobin-induced intracerebral hemorrhage

(2016) Bo Ma et al.   Journal of Neuroinflammation

Differential heme release from various hemoglobin redox states and the upregulation of cellular heme oxygenase-1

(2016) Tigist Kassa et al.   FEBS Open Bio

Low Density Lipoprotein-Receptor Related Protein 1 Is Differentially Expressed by Neuronal and Glial Populations in the Developing and Mature Mouse Central Nervous System

(2016) Loic Auderset et al.   PLoS One

Significant glial alterations in response to iron loading in a novel organotypic hippocampal slice culture model

(2016) Sinead Healy et al.   Scientific Reports

Different target specificities of haptoglobin and hemopexin define a sequential protection system against vascular hemoglobin toxicity

(2015) Jeremy W. Deuel et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hemopexin and haptoglobin: allies against heme toxicity from hemoglobin not contenders

(2015) Ann Smith et al.   Frontiers in Physiology

Uptake and metabolism of iron and iron oxide nanoparticles in brain astrocytes: Figure 1

(2015) Michaela C. Hohnholt et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Hemolysis and free hemoglobin revisited: exploring hemoglobin and hemin scavengers as a novel class of therapeutic proteins

(2012) D. J. Schaer et al.   BLOOD

Identification of Hemopexin as an Anti-Inflammatory Factor That Inhibits Synergy of Hemoglobin with HMGB1 in Sterile and Infectious Inflammation

(2012) T. Lin et al.   JOURNAL OF IMMUNOLOGY

The intrathecal CD163-haptoglobin-hemoglobin scavenging system in subarachnoid hemorrhage

(2012) James Galea et al.   JOURNAL OF NEUROCHEMISTRY

Heme activates TLR4-mediated inflammatory injury via MyD88/TRIF signaling pathway in intracerebral hemorrhage

(2012) Sen Lin et al.   Journal of Neuroinflammation

Hemopexin decreases hemin accumulation and catabolism by neural cells

(2012) Jing Chen-Roetling et al.   NEUROCHEMISTRY INTERNATIONAL

Reduction of low-density lipoprotein receptor-related protein (LRP1) in hippocampal neurons does not proportionately reduce, or otherwise alter, amyloid deposition in APPswe/PS1dE9 transgenic mice

(2012) Guilian Xu et al.   Alzheimers Research & Therapy

Kinetics and Specificity of Feline Leukemia Virus Subgroup C Receptor (FLVCR) Export Function and Its Dependence on Hemopexin

(2010) Zhantao Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased striatal injury and behavioral deficits after intracerebral hemorrhage in hemopexin knockout mice

(2010) Lifen Chen et al.   JOURNAL OF NEUROSURGERY

Quantitative Mass Spectrometry-based Proteomics Reveals the Dynamic Range of Primary Mouse Astrocyte Protein Secretion

(2010) Todd M. Greco et al.   JOURNAL OF PROTEOME RESEARCH

Apotransferrin protects cortical neurons from hemoglobin toxicity

(2010) Jing Chen-Roetling et al.   NEUROPHARMACOLOGY

Heme Scavenging and the Other Facets of Hemopexin

(2009) Emanuela Tolosano et al.   ANTIOXIDANTS & REDOX SIGNALING

Increasing expression of H- or L-ferritin protects cortical astrocytes from hemin toxicity

(2009) Zhi Li et al.   FREE RADICAL RESEARCH

Heme–Hemopexin Complex Attenuates Neuronal Cell Death and Stroke Damage

(2009) Rung-chi Li et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

On the Fate of Extracellular Hemoglobin and Heme in Brain

(2009) Flavio A Lara et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Neuroprotective Role of Haptoglobin after Intracerebral Hemorrhage

(2009) X. Zhao et al.   JOURNAL OF NEUROSCIENCE

Neurons lacking iron regulatory protein-2 are highly resistant to the toxicity of hemoglobin

(2008) Raymond F. Regan et al.   NEUROBIOLOGY OF DISEASE

A Heme Export Protein Is Required for Red Blood Cell Differentiation and Iron Homeostasis

(2008) S. B. Keel et al.   SCIENCE