Quantitative assessment of surface functionality effects on microglial uptake and retention of PAMAM dendrimers

PAMAM Dendrimers Cross the Blood–Brain Barrier When Administered through the Carotid Artery in C57BL/6J Mice

(2017) Bhairavi Srinageshwar et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Generation-6 hydroxyl PAMAM dendrimers improve CNS penetration from intravenous administration in a large animal brain injury model

(2017) Fan Zhang et al.   JOURNAL OF CONTROLLED RELEASE

Dendrimer-mediated delivery of N-acetyl cysteine to microglia in a mouse model of Rett syndrome

(2017) Elizabeth Nance et al.   Journal of Neuroinflammation

Effects of Surface Charge of Hyperbranched Polymers on Cytotoxicity, Dynamic Cellular Uptake and Localization, Hemotoxicity, and Pharmacokinetics in Mice

(2017) Liyu Chen et al.   MOLECULAR PHARMACEUTICS

Dendrimers as Nanocarriers for Nucleic Acid and Drug Delivery in Cancer Therapy

(2017) Livia Palmerston Mendes et al.   MOLECULES

Uptake of dendrimer-drug by different cell types in the hippocampus after hypoxic–ischemic insult in neonatal mice: Effects of injury, microglial activation and hypothermia

(2017) Christina L. Nemeth et al.   Nanomedicine-Nanotechnology Biology and Medicine

Nanotoxicological and teratogenic effects: A linkage between dendrimer surface charge and zebrafish developmental stages

(2017) Maria Natalia Calienni et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Impact of Dendrimers on Solubility of Hydrophobic Drug Molecules

(2017) Sonam Choudhary et al.   Frontiers in Pharmacology

Bench-to-bedside translation of dendrimers: Reality or utopia? A concise analysis

(2017) Serge Mignani et al.   ADVANCED DRUG DELIVERY REVIEWS

Nanoscale effects in dendrimer-mediated targeting of neuroinflammation

(2016) Elizabeth Nance et al.   BIOMATERIALS

Cellular Uptake of Gold Nanoparticles and Their Behavior as Labels for Localization Microscopy

(2016) Felipe Moser et al.   BIOPHYSICAL JOURNAL

The Cell Nucleus Serves as a Mechanotransducer of Tissue Damage-Induced Inflammation

(2016) Balázs Enyedi et al.   CELL

Dendrimer-mediated approaches for the treatment of brain tumor

(2016) Nitin Dwivedi et al.   JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION

Uptake of silver nanoparticles by monocytic THP-1 cells depends on particle size and presence of serum proteins

(2016) Katja Kettler et al.   JOURNAL OF NANOPARTICLE RESEARCH

Microglial migration and interactions with dendrimer nanoparticles are altered in the presence of neuroinflammation

(2016) Fan Zhang et al.   Journal of Neuroinflammation

Effects of PAMAM dendrimers with various surface functional groups and multiple generations on cytotoxicity and neuronal differentiation using human neural progenitor cells

(2016) Yang Zeng et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Reverse Size Dependences of the Cellular Uptake of Triangular and Spherical Gold Nanoparticles

(2016) Katsuyuki Nambara et al.   LANGMUIR

Dendrimers Target the Ischemic Lesion in Rodent and Primate Models of Nonarteritic Anterior Ischemic Optic Neuropathy

(2016) Yan Guo et al.   PLoS One

Uniform brain tumor distribution and tumor associated macrophage targeting of systemically administered dendrimers

(2015) Fan Zhang et al.   BIOMATERIALS

Intracellular delivery of dendrimer triamcinolone acetonide conjugates into microglial and human retinal pigment epithelial cells

(2015) Siva P. Kambhampati et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

PAMAM dendrimers as promising nanocarriers for RNAi therapeutics

(2015) Prashant Kesharwani et al.   Materials Today

Surface modification of microparticles causes differential uptake responses in normal and tumoral human breast epithelial cells

(2015) Tania Patiño et al.   Scientific Reports

Dendrimer Brain Uptake and Targeted Therapy for Brain Injury in a Large Animal Model of Hypothermic Circulatory Arrest

(2014) Manoj K. Mishra et al.   ACS Nano

64Cu-Labeled LyP-1-Dendrimer for PET-CT Imaging of Atherosclerotic Plaque

(2014) Jai Woong Seo et al.   BIOCONJUGATE CHEMISTRY

Folate-functionalized dendrimers for targeting Chlamydia-infected tissues in a mouse model of reactive arthritis

(2014) Ilyes Benchaala et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Emerging concepts in dendrimer-based nanomedicine: from design principles to clinical applications

(2014) R. M. Kannan et al.   JOURNAL OF INTERNAL MEDICINE

Cytokine Secretion in Macrophages: SNAREs, Rabs, and Membrane Trafficking

(2014) Rachael Zoe Murray et al.   Frontiers in Immunology

Effect of Polyplex Morphology on Cellular Uptake, Intracellular Trafficking, and Transgene Expression

(2013) Julie Shi et al.   ACS Nano

Exocytosis of nanoparticles from cells: Role in cellular retention and toxicity

(2013) Ramin Sakhtianchi et al.   ADVANCES IN COLLOID AND INTERFACE SCIENCE

A novel dendritic nanocarrier of polyamidoamine-polyethylene glycol-cyclic RGD for “smart” small interfering RNA delivery and in vitro antitumor effects by human ether-à-go-go-related gene silencing in anaplastic thyroid carcinoma cells

(2013) Guanhua Li et al.   International Journal of Nanomedicine

LPS or ethanol triggers clathrin- and rafts/caveolae-dependent endocytosis of TLR4 in cortical astrocytes

(2013) Maya Pascual-Lucas et al.   JOURNAL OF NEUROCHEMISTRY

Surface and Size Effects on Cell Interaction of Gold Nanoparticles with Both Phagocytic and Nonphagocytic Cells

(2013) Xiangsheng Liu et al.   LANGMUIR

Biodistribution of Fluorescently Labeled PAMAM Dendrimers in Neonatal Rabbits: Effect of Neuroinflammation

(2013) Wojciech G. Lesniak et al.   MOLECULAR PHARMACEUTICS

Cationic PAMAM Dendrimers Aggressively Initiate Blood Clot Formation

(2012) Clinton F. Jones et al.   ACS Nano

The Effect of Nanoparticle Size, Shape, and Surface Chemistry on Biological Systems

(2012) Alexandre Albanese et al.   Annual Review of Biomedical Engineering

Effect of Size, Surface Charge, and Hydrophobicity of Poly(amidoamine) Dendrimers on Their Skin Penetration

(2012) Yang Yang et al.   BIOMACROMOLECULES

The Possible “Proton Sponge ” Effect of Polyethylenimine (PEI) Does Not Include Change in Lysosomal pH

(2012) Rikke V Benjaminsen et al.   MOLECULAR THERAPY

Dendrimer-Based Postnatal Therapy for Neuroinflammation and Cerebral Palsy in a Rabbit Model

(2012) S. Kannan et al.   Science Translational Medicine

CD14 Controls the LPS-Induced Endocytosis of Toll-like Receptor 4

(2011) Ivan Zanoni et al.   CELL

Dendrimer-based drug and imaging conjugates: design considerations for nanomedical applications

(2010) Anupa R. Menjoge et al.   DRUG DISCOVERY TODAY

Dendrimer toxicity: Let's meet the challenge

(2010) Keerti Jain et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Toxicity and cellular uptake of gold nanoparticles: what we have learned so far?

(2010) Alaaldin M. Alkilany et al.   JOURNAL OF NANOPARTICLE RESEARCH

Dendrimer Internalization and Intracellular Trafficking in Living Cells

(2010) Lorenzo Albertazzi et al.   MOLECULAR PHARMACEUTICS

Surface Modification of PAMAM Dendrimers Modulates the Mechanism of Cellular Internalization

(2009) Angkana Saovapakhiran et al.   BIOCONJUGATE CHEMISTRY

A perinuclear actin cap regulates nuclear shape

(2009) Shyam B. Khatau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Size, charge and concentration dependent uptake of iron oxide particles by non-phagocytic cells

(2008) Daniel L.J. Thorek et al.   BIOMATERIALS

The effect of surface functionality on cellular trafficking of dendrimers

(2008) Omathanu P. Perumal et al.   BIOMATERIALS