Homocysteine and A2A-D2 Receptor-Receptor Interaction at Striatal Astrocyte Processes

The Role of Astrocyte Dysfunction in Parkinson’s Disease Pathogenesis

(2017) Heather D.E. Booth et al.   TRENDS IN NEUROSCIENCES

G Protein–Coupled Receptor Heteromers

(2016) Ivone Gomes et al.   Annual Review of Pharmacology and Toxicology

L-DOPA-induced hyperhomocysteinemia in Parkinson's disease: Elephant in the room

(2016) Rajib Paul et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

A2A-D2 receptor-receptor interaction modulates gliotransmitter release from striatal astrocyte processes

(2016) Chiara Cervetto et al.   JOURNAL OF NEUROCHEMISTRY

Deep brain stimulation mechanisms: the control of network activity via neurochemistry modulation

(2016) Cameron C. McIntyre et al.   JOURNAL OF NEUROCHEMISTRY

Current and experimental treatments of Parkinson disease: A guide for neuroscientists

(2016) Wolfgang Oertel et al.   JOURNAL OF NEUROCHEMISTRY

Role of iso-receptors in receptor-receptor interactions with a focus on dopamine iso-receptor complexes

(2016) Luigi F. Agnati et al.   REVIEWS IN THE NEUROSCIENCES

Basic Pharmacological and Structural Evidence for Class A G-Protein-Coupled Receptor Heteromerization

(2016) Rafael Franco et al.   Frontiers in Pharmacology

Perisynaptic astroglial processes: dynamic processors of neuronal information

(2015) Grégory Ghézali et al.   Brain Structure & Function

Metabolic, synaptic and behavioral impact of 5-week chronic deep brain stimulation in hemiparkinsonian rats

(2015) Carine Chassain et al.   JOURNAL OF NEUROCHEMISTRY

Volume Transmission in Central Dopamine and Noradrenaline Neurons and Its Astroglial Targets

(2015) Kjell Fuxe et al.   NEUROCHEMICAL RESEARCH

Astrocyte-Dependent Vulnerability to Excitotoxicity in Spermine Oxidase-Overexpressing Mouse

(2015) Chiara Cervetto et al.   NEUROMOLECULAR MEDICINE

Calcium-permeable AMPA receptors trigger vesicular glutamate release from Bergmann gliosomes

(2015) Chiara Cervetto et al.   NEUROPHARMACOLOGY

Oxaliplatin evokes P2X7-dependent glutamate release in the cerebral cortex: A pain mechanism mediated by Pannexin 1

(2015) Lorenzo Di Cesare Mannelli et al.   NEUROPHARMACOLOGY

On the role of the extracellular space on the holistic behavior of the brain

(2015) Manuela Marcoli et al.   REVIEWS IN THE NEUROSCIENCES

Circuit-specific signaling in astrocyte-neuron networks in basal ganglia pathways

(2015) R. Martin et al.   SCIENCE

Morphological changes of glutamatergic synapses in animal models of Parkinson’s disease

(2015) Rosa M. Villalba et al.   Frontiers in Neuroanatomy

Intracellular Calcium Levels Determine Differential Modulation of Allosteric Interactions within G Protein-Coupled Receptor Heteromers

(2014) Gemma Navarro et al.   CHEMISTRY & BIOLOGY

Activity-Dependent Structural Plasticity of Perisynaptic Astrocytic Domains Promotes Excitatory Synapse Stability

(2014) Yann Bernardinelli et al.   CURRENT BIOLOGY

“Neuro-Semeiotics” and “Free-Energy Minimization” Suggest a Unified Perspective for Integrative Brain Actions: Focus on Receptor Heteromers and Roamer Type of Volume Transmission

(2014) Luigi Agnati et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

G-protein-coupled receptor type A heteromers as an emerging therapeutic target

(2014) Diego Guidolin et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Synthesis and Pharmacological Evaluation of Dual Acting Ligands Targeting the Adenosine A2A and Dopamine D2 Receptors for the Potential Treatment of Parkinson’s Disease

(2014) Manuela Jörg et al.   JOURNAL OF MEDICINAL CHEMISTRY

Increased striatal adenosine A2A receptor levels is an early event in Parkinson’s disease-related pathology and it is potentially regulated by miR-34b

(2014) Izaskun Villar-Menéndez et al.   NEUROBIOLOGY OF DISEASE

Flow Synthesis and Biological Studies of an Analgesic Adamantane Derivative That Inhibits P2X7-Evoked Glutamate Release

(2013) Claudio Battilocchio et al.   ACS Medicinal Chemistry Letters

Suppression of neuroinflammation by astrocytic dopamine D2 receptors via αB-crystallin

(2012) Wei Shao et al.   NATURE

Calmidazolium selectively inhibits exocytotic glutamate release evoked by P2X7 receptor activation

(2012) Chiara Cervetto et al.   NEUROCHEMISTRY INTERNATIONAL

Potentiation of NMDA Receptor-Dependent Cell Responses by Extracellular High Mobility Group Box 1 Protein

(2012) Marco Pedrazzi et al.   PLoS One

The Role of Extracellular Adenosine in Chemical Neurotransmission in the Hippocampus and Basal Ganglia: Pharmacological and Clinical Aspects

(2011) Beata Sperlagh et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

VGLUT1 is localized in astrocytic processes in several brain regions

(2011) Lasse Ormel et al.   GLIA

Calcium Triggers Exocytosis from Two Types of Organelles in a Single Astrocyte

(2011) T. Liu et al.   JOURNAL OF NEUROSCIENCE

Structural plasticity of perisynaptic astrocyte processes involves ezrin and metabotropic glutamate receptors

(2011) M. Lavialle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Morphology and dynamics of perisynaptic glia

(2010) Andreas Reichenbach et al.   BRAIN RESEARCH REVIEWS

Missing pieces in the Parkinson's disease puzzle

(2010) Jose A Obeso et al.   NATURE MEDICINE

Urotensin II receptor and acetylcholine release from mouse cervical spinal cord nerve terminals

(2010) F. Bruzzone et al.   NEUROSCIENCE

Seven Transmembrane Receptors as Shapeshifting Proteins: The Impact of Allosteric Modulation and Functional Selectivity on New Drug Discovery

(2010) T. Kenakin et al.   PHARMACOLOGICAL REVIEWS

Molecular integration via allosteric interactions in receptor heteromers. A working hypothesis

(2009) Kjell Fuxe et al.   CURRENT OPINION IN PHARMACOLOGY

Adenosine A2AReceptor-Antagonist/Dopamine D2Receptor-Agonist Bivalent Ligands as Pharmacological Tools to Detect A2A-D2Receptor Heteromers

(2009) Aroa Soriano et al.   JOURNAL OF MEDICINAL CHEMISTRY

Inhibition of Presynaptic Release-Facilitatory Kainate Autoreceptors by Extracellular Cyclic GMP

(2009) C. Cervetto et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Hyperhomocysteinemia in levodopa-treated patients with Parkinson's disease dementia

(2009) Stefano Zoccolella et al.   MOVEMENT DISORDERS

Receptor–receptor interactions: A novel concept in brain integration

(2009) Luigi F. Agnati et al.   PROGRESS IN NEUROBIOLOGY

Tripartite synapses: astrocytes process and control synaptic information

(2009) Gertrudis Perea et al.   TRENDS IN NEUROSCIENCES

Adenosine A2Areceptor antagonists exert motor and neuroprotective effects by distinct cellular mechanisms

(2008) Liqun Yu et al.   ANNALS OF NEUROLOGY

Dopamine D2 and Adenosine A2A Receptors Regulate NMDA-Mediated Excitation in Accumbens Neurons Through A2A–D2 Receptor Heteromerization

(2008) Karima Azdad et al.   NEUROPSYCHOPHARMACOLOGY

Morphological evidence for vesicular glutamate release from astrocytes

(2008) L.H. Bergersen et al.   NEUROSCIENCE

Structural plasticity in G-protein coupled receptors as demonstrated by the allosteric actions of homocysteine and computer-assisted analysis of disordered domains

(2007) L.F. Agnati et al.   BRAIN RESEARCH REVIEWS