Article
Materials Science, Multidisciplinary
Zhenyang Ji, Jinrong Yao, Zhengzhong Shao, Xin Chen
Summary: This study developed zein/chitosan composite nanospheres as carriers for controlled release of cinnamaldehyde (CA) in cosmetics industry. The structure of the nanospheres was influenced by the zein/chitosan mass ratio. The interaction between CA and zein, as well as the formation of Schiff base between CA and chitosan, effectively reduced the volatilization rate of CA and prolonged its release time.
Article
Polymer Science
Carlos Enrique Osorio-Alvarado, Jose Luis Ropero-Vega, Ana Elvira Farfan-Garcia, Johanna Marcela Florez-Castillo
Summary: This study synthesized alginate and chitosan nanoparticles using the ionic gelation technique and immobilized the Ib-M1 peptide to form an Ib-M1/Alg-Chi bioconjugate. The results showed that the bioconjugate exhibited good biological activity and stability, making it a potential antimicrobial agent.
Article
Food Science & Technology
Masomeh Valizadeh, Mahdi Behnamian, Sara Dezhsetan, Roghayeh Karimirad
Summary: The study demonstrated that the use of turmeric oil incorporated chitosan nanoparticles (TEO-CSNPs) significantly enhanced the shelf life of white button mushrooms, extending the storage period of the fruit bodies. The treatment with TEO-CSNPs resulted in firmer mushrooms with lower color changes and microbial counts, as well as increased antioxidant enzyme activity and antioxidant content in the fruit bodies.
Review
Pharmacology & Pharmacy
Rizwan Safdar, Murugesan Thanabalan
Summary: Diabetes is a major health issue requiring appropriate insulin delivery. The use of chitosan nanoparticles and microparticles has shown potential in insulin delivery and controlled release. The study also highlights the barriers of oral delivery and the importance of chitosan modification.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Gabriel Marcelino-Perez, Roberto Ruiz-Medrano, Salvador Gallardo-Hernandez, Beatriz Xoconostle-Cazares
Summary: This study evaluated the antimicrobial activity of mesoporous silica nanoparticles loaded with human beta-defensin-2 and its mutants against Clavibacter michiganensis subsp. michiganensis. The results showed that the MSN loaded with AMPs inhibited the growth of Cmm and protected AMPs from enzymatic degradation.
Article
Chemistry, Applied
Yuchen Huan, Qing Kong, Qingjuan Tang, Yuming Wang, Haijin Mou, Rui Ying, Chunjun Li
Summary: This study developed a hydrogel by grafting self-assembling peptides onto O-carboxymethyl chitosan, which exhibited sustained drug release effect and promoted wound closure and skin tissue regeneration.
CARBOHYDRATE POLYMERS
(2022)
Article
Chemistry, Analytical
Zhuoyun Tang, Zeliang Wei, Ke Huang, Yinhao Wei, Dongdong Li, Shixin Yan, Jin Huang, Jia Geng, Chuanmin Tao, Piaopiao Chen, Binwu Ying
Summary: The newly developed method for detecting HIV-1 p24 antigen demonstrates high sensitivity and selectivity, allowing for the detection of as low as 1 pg/mL of antigen by naked eyes. The analysis of clinical samples using this method shows good consistency with clinical data, and the method can accurately distinguish HIV infection from other viruses and infections.
Article
Biochemistry & Molecular Biology
Enchao Liu, Shenghan Zhao, Xiao Li, Xianghong Meng, Bingjie Liu
Summary: In this study, a novel DHA-loaded nanoparticle (PCSDNP) with PLGA and chitosan was successfully prepared. The particle structure and interactions were analyzed through various microscopy techniques and FTIR spectroscopy. PCSDNP showed better stability and controlled release properties under different environmental conditions, mainly attributed to hydrogen bonds and electrostatic interactions between PLGA and chitosan, demonstrating potential for biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Multidisciplinary Sciences
Ghulam Abbas, Akhtar Rasul, M. Fakhar-e-Alam, Malik Saadullah, Saima Muzammil, Omeira Iqbal, M. Atif, Muhammad Hanif, Shahid Shah, Shafiq Ahmad, Sulman Shafeeq, Muhammad Afzal
Summary: The study aimed to formulate nanoparticles of thiolated chitosan with enhanced mucoadhesion and controlled release behavior. Stable nanoparticles were prepared using an ionic gelation method, and their adhesion, swelling, and toxicity were evaluated. Drug release studies of non-thiolated and thiolated nanoparticles showed that the thiolated nanoparticles exhibited better controlled release. Animal experiments confirmed the superior pharmacokinetic properties of the thiolated nanoparticles compared to the marketed formulation.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Ioana-Victoria Platon, Claudiu-Augustin Ghiorghita, Maria Marinela Lazar, Irina Elena Raschip, Maria Valentina Dinu
Summary: New chitosan sponges with multiple functions were prepared by glutaraldehyde cross-linking and showed excellent antibacterial, antioxidant, and controlled delivery properties. The sponges exhibited complete shape recovery after compression, effective antibacterial activity against different strains, and good radical scavenging activity. The release of curcumin from the sponges relied on their composition and preparation strategy, and a pseudo-Fickian diffusion release mechanism was observed.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Weiwei Li, Di Liu, Laicui Song, Hao Li, Shijie Dai, Ya Su, Qianjin Li, Jianlin Li, Tiesong Zheng
Summary: Surface modified pH-responsive porous silicon (PSi) carriers were developed for efficient delivery of lutein. The chitosan-coated oxidized PSi can effectively deliver lutein in a targeted and controlled manner and show good biocompatibility in vivo.
Article
Biochemistry & Molecular Biology
Diogo B. Bitoque, Joana Morais, Ana V. Oliveira, Raquel L. Sequeira, Sofia M. Calado, Tiago M. Fortunato, Sonia Simao, Ana M. Rosa da Costa, Gabriela A. Silva
Summary: This study found that co-complexation or covalent ligation of IGFBP-3 derived NLS peptide with chitosan polyplexes can enhance the efficiency of non-viral vectors, showing a 2-fold increase in transfection efficiency.
BIOSCIENCE REPORTS
(2021)
Article
Multidisciplinary Sciences
Jinrong Liu, Mika H. Sipponen
Summary: This study presents a bio-based nanocomposite film composed of chitosan, lignin nanoparticles, glutaraldehyde, and silver nanoparticles. The film demonstrates remarkable photothermally triggered antibacterial effect and high absorption of solar radiation, making it suitable for sunlight-activated antimicrobial films and coatings.
Article
Chemistry, Applied
Jingbo Liu, Yajuan Li, Hui Zhang, Shitong Liu, Meng Yang, Meiyan Cui, Ting Zhang, Yiding Yu, Hang Xiao, Zhiyang Du
Summary: Food-derived peptides have exhibited promising bioactivities and multimeric structures, making them potential nanoplatform candidates for co-delivery with other bioactive compounds; Zein-egg white derived peptides-chitosan ternary nanoparticles have been successfully fabricated by spontaneous assembly, enhancing the stability and bioactivity of curcumin and improving antioxidant activity.
Article
Chemistry, Multidisciplinary
Nechikkottil Sivadasan Sumitha, Prabha Prakash, Balagopal N. Nair, Gopalakrishnanchettiar Sivakamiammal Sailaja
Summary: Glyoxal cross-linked porous magnetic chitosan microspheres (GMS) were synthesized using a water-in-oil emulsion technique for controlled delivery of doxorubicin (DOX) with prolonged chemotherapeutic effects. GMS exhibited superparamagnetism and excellent cytocompatibility, with a release mechanism involving diffusion-inspired release through the swollen polymer network and regulated degradation release.
Article
Chemistry, Physical
Rajalaxmi Sahoo, C. Reshma, D. S. Shankar Rao, C. V. Yelamaggad, S. Krishna Prasad
Summary: This study investigates the influence of the flexible spacer parity of a guest photoactive liquid crystalline dimer on the photonic bandgap features of the cholesteric and twist grain boundary smectic C phases of the host molecule. The results show that the parity of the photoactive dimer affects the width of the photonic bandgap and the blue-shift of the cholesteric phase. Additionally, the parity of the dimer also affects the layer spacing and two-dimensional periodicity of the liquid crystalline phases.
JOURNAL OF MOLECULAR LIQUIDS
(2024)
Article
Chemistry, Physical
Sara Rozas, Alberto Gutierrez, Mert Atilhan, Alfredo Bol, Santiago Aparicio
Summary: This study presents a multiscale theoretical investigation on the use of bifunctional hydrophobic Deep Eutectic Solvent for carbon capture using tetrapropylammonium chloride, acetic acid, and ethanolamine. The characterization includes nanoscale analysis of CO2 absorption mechanisms and changes in liquid phase properties during gas capture.
JOURNAL OF MOLECULAR LIQUIDS
(2024)
Article
Chemistry, Physical
Tabouli Eric Da-yang, Alhadji Malloum, Jean Jules Fifen, Mama Nsangou, Jeanet Conradie
Summary: In this study, the potential energy of different glycine tautomers and their interaction with Cu2+ cations was investigated. The results showed that the solvation medium and the presence of Cu2+ cations influenced the stability of glycine tautomers.
JOURNAL OF MOLECULAR LIQUIDS
(2024)
Article
Chemistry, Physical
Xiaoliang Gou, Nan Ye, Qingqing Han, Junjie Cui, Long Yi Jin
Summary: In this study, amphiphilic rod-coil molecules with rigid DSA parts and flexible oligoether chains were designed and their assembly capacities were investigated. The morphology of the molecular aggregates was influenced by the pH of the solution and UV light, and the aggregates showed adsorption capacity for nitroaromatic compounds.
JOURNAL OF MOLECULAR LIQUIDS
(2024)
Article
Chemistry, Physical
Shuang Liu, Liyan Shan, Cong Qi, Wenhui Zhang, Guannan Li, Bei Wang, Wei Wei
Summary: Optimizing the design of styrene-butadiene-styrene copolymer (SBS) is crucial for producing cost-effective SBS modifiers and improving road quality. This study examined the influence of SBS content and molecular structure on viscosity and compatibility. The results showed that the viscosity contribution of SBS is determined by its molecular structure and phase morphology.
JOURNAL OF MOLECULAR LIQUIDS
(2024)
Article
Chemistry, Physical
Artem A. Petrov, Ekaterina A. Titova, Aydar A. Akhmadiyarov, Ilnaz T. Rakipov, Boris N. Solomonov
Summary: This work focuses on the thermochemistry of solvation of azeotropes. The enthalpies of dissolution of azeotropes in different mediums were determined, and the impact of the structure of the azeotropes on their properties in solution was discussed. A correlation between enthalpies of solvation and molar refraction was used to determine the vaporization enthalpies of azeotropes for the first time. The results were found to be consistent with literature data, obtained using direct and calculated methods. These findings contribute to the analysis of the structure-property relationships of azeotropes.
JOURNAL OF MOLECULAR LIQUIDS
(2024)
Article
Chemistry, Physical
L. V. Kamaeva, E. N. Tsiok, N. M. Chtchelkatchev
Summary: Understanding the correlations between liquids and solids allows us to predict the thermodynamic parameter range favorable for the formation of intriguing solid phases by studying liquids. In this study, we experimentally and theoretically investigated an Al-Cu-Co system within different composition ranges, and identified high-temperature solid phases. Our findings demonstrated the correlation between the boundaries of different solid phases and undercooling and viscosity in the concentration area.
JOURNAL OF MOLECULAR LIQUIDS
(2024)
Article
Chemistry, Physical
R. Aneesh Kumar, S. Jamelah Al-Otaibi, Y. Sheena Mary, Y. Shyma Mary, Nivedita Acharjee, Renjith Thomas, Renjith Raveendran Pillai, T. L. Leena
Summary: In this study, the interactions between doped and pristine coronenes and adenine nucleobases were investigated using Density Functional Theory. The optimal configurations, adsorption energies, charge transfer, and electrical properties of each complex were calculated. It was found that doped coronene had stronger adsorption strength and charge transfer compared to pristine coronene. The stability of the complexes was attributed to non-covalent interactions in the interactive region. The change in electrical conductivity of coronenes after adsorption suggested their sensitivity towards DNA bases. The predicted energy gap and prolonged recovery time for adenine-coronene configurations indicated the potential application of pristine/doped coronene in DNA detection.
JOURNAL OF MOLECULAR LIQUIDS
(2024)
Article
Chemistry, Physical
Gang Zhou, Yongwei Liu, Biao Sun, Zengxin Liu, Cuicui Xu, Rulin Liu, Qi Zhang, Yongmei Wang
Summary: The CFD-DEM method was used to simulate the dust deposition pattern in the bronchus of anchor digging drivers, revealing the highest dust concentration in the vortex region of the working face. The study also found a positive correlation between dust particle diameter and bronchial deposition rate, and a negative correlation with alveolar deposition rate.
JOURNAL OF MOLECULAR LIQUIDS
(2024)
Article
Chemistry, Physical
Yan Zhang, Yafei Luo, Lingkai Tang, Mingyan E, Jianping Hu
Summary: This study investigates the effects of different transition metal decorations on B12N12 nanocages on the adsorption properties of nitrosourea drugs using computational methods. The results reveal the presence of weak non-covalent interactions between metals and nanocages, and the interaction between drugs and nanocages plays a significant role in drug adsorption. Compared to free drugs, the adsorption of drugs on nanocages can facilitate electron transfer, reduce energy gaps and chemical hardness, indicating activity at the target site.
JOURNAL OF MOLECULAR LIQUIDS
(2024)
Article
Chemistry, Physical
C. I. Alcolado, J. Poblete, L. Garcia-Rio, E. Jimenez, F. J. Poblete
Summary: In this study, the selective oxidation of aromatic aldehydes was investigated using Ru(VI) as a catalyst and hexacyanoferrate (III) as a cooxidant in an alkaline medium. The reaction mechanism involves complex reaction orders for the oxidant and the aromatic aldehyde, while the reaction order for Ru(VI) is one. The proposed mechanism includes two catalytic cycles and the formation and decomposition of complexes. Quantitative structure-activity relationship analysis showed that deactivating groups in the para-position enhance the process.
JOURNAL OF MOLECULAR LIQUIDS
(2024)
Article
Chemistry, Physical
Inez A. Barbieri, Marcos L. S. Oliveira, Franciele S. Bruckmann, Theodoro R. Salles, Leonardo Zancanaro, Luis F. O. Silva, Guilherme L. Dotto, Eder C. Lima, Mu. Naushad, Cristiano R. Bohn Rhoden
Summary: This study evaluated the adsorption of zolpidem on magnetic graphene oxide and synthesized magnetic graphene oxide adsorbents for zolpidem removal. The best magnetic nanoadsorbent was found to have a removal percentage of 87.07% at specific pH and temperature conditions. The results suggest that the removal of zolpidem is related to the surface chemistry of the adsorbent rather than the surface area of graphene oxide. The adsorbent showed excellent adsorption efficiency and magnetic behavior, making it a promising material for removing zolpidem from aqueous solutions.
JOURNAL OF MOLECULAR LIQUIDS
(2024)
Article
Chemistry, Physical
Hongyan Huang, Chunquan Li, Siyuan Huang, Yuling Shang
Summary: This study examines the sensitivity of the thermal conductivity of water-based alumina nanofluids to changes in concentration, sphericity, and temperature. The results show that volume fraction and temperature have a significant impact on the thermal conductivity, while sphericity also needs to be considered. A support vector machine regression model was created to analyze the sensitivity of the thermal conductivity to different parameters. The findings indicate that temperature, sphericity, and volume fraction are the most sensitive variables.
JOURNAL OF MOLECULAR LIQUIDS
(2024)
Correction
Chemistry, Physical
V. M. Pergamenshchik, T. Bryk, A. Trokhymchuk
JOURNAL OF MOLECULAR LIQUIDS
(2024)
Article
Chemistry, Physical
Valentyn Rudenko, Anatolii Tolochko, Svitlana Bugaychuk, Dmytro Zhulai, Gertruda Klimusheva, Galina Yaremchuk, Tatyana Mirnaya, Yuriy Garbovskiy
Summary: This paper reports on the synthesis, structural characterization, spectral and nonlinear-optical properties of glass nanocomposites made of glass forming ionic liquid crystals and nanoparticles. The study reveals that by exciting the nanocomposites within their absorption band, a control over effective optical nonlinearities can be achieved, allowing the modification of the magnitude and sign of the effective nonlinear absorption coefficient. The proposed strategy using metal-alkanoates based glass-forming ionic liquid crystals and nanoparticles shows great potential for the development of nanophotonics and plasmonics technologies.
JOURNAL OF MOLECULAR LIQUIDS
(2024)