Design and Synthesis of Clinical Candidate PF-06751979: A Potent, Brain Penetrant, β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor Lacking Hypopigmentation

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Title
Design and Synthesis of Clinical Candidate PF-06751979: A Potent, Brain Penetrant, β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor Lacking Hypopigmentation
Authors
Keywords
-
Journal
JOURNAL OF MEDICINAL CHEMISTRY
Volume 61, Issue 10, Pages 4476-4504
Publisher
American Chemical Society (ACS)
Online
2018-04-04
DOI
10.1021/acs.jmedchem.8b00246

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