Metabolic regulator LKB1 is crucial for Schwann cell–mediated axon maintenance

LKB1 Inactivation Dictates Therapeutic Response of Non-Small Cell Lung Cancer to the Metabolism Drug Phenformin

(2013) David B. Shackelford et al.   CANCER CELL

The regulation and function of the NUAK family

(2013) Xianglan Sun et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Aberrant Schwann Cell Lipid Metabolism Linked to Mitochondrial Deficits Leads to Axon Degeneration and Neuropathy

(2013) Andreu Viader et al.   NEURON

Why Are Sensory Axons More Vulnerable for Ischemia than Motor Axons?

(2013) Jeannette Hofmeijer et al.   PLoS One

Lkb1/Stk11 regulation of mTOR signaling controls the transition of chondrocyte fates and suppresses skeletal tumor formation

(2013) L. P. Lai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Concepts for regulation of axon integrity by enwrapping glia

(2013) Bogdan Beirowski   Frontiers in Cellular Neuroscience

The Phr1 Ubiquitin Ligase Promotes Injury-Induced Axon Self-Destruction

(2013) Elisabetta Babetto et al.   Cell Reports

Genetic disruption ofPtenin a novel mouse model of tomaculous neuropathy

(2012) Sandra Goebbels et al.   EMBO Molecular Medicine

Arrest of Myelination and Reduced Axon Growth When Schwann Cells Lack mTOR

(2012) D. L. Sherman et al.   JOURNAL OF NEUROSCIENCE

The AMPK  2 Subunit Is Required for Energy Homeostasis during Metabolic Stress

(2012) B. Dasgupta et al.   MOLECULAR AND CELLULAR BIOLOGY

Oligodendroglia metabolically support axons and contribute to neurodegeneration

(2012) Youngjin Lee et al.   NATURE

Meta-analysis of untargeted metabolomic data from multiple profiling experiments

(2012) Gary J Patti et al.   Nature Protocols

AMPK: a nutrient and energy sensor that maintains energy homeostasis

(2012) D. Grahame Hardie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The role of aberrant mitochondrial bioenergetics in diabetic neuropathy

(2012) Subir K. Roy Chowdhury et al.   NEUROBIOLOGY OF DISEASE

A Central Role for the ERK-Signaling Pathway in Controlling Schwann Cell Plasticity and Peripheral Nerve Regeneration In Vivo

(2012) Ilaria Napoli et al.   NEURON

c-Jun Reprograms Schwann Cells of Injured Nerves to Generate a Repair Cell Essential for Regeneration

(2012) Peter J. Arthur-Farraj et al.   NEURON

Expanding Coverage of the Metabolome for Global Metabolite Profiling

(2011) Oscar Yanes et al.   ANALYTICAL CHEMISTRY

AMPK and mTOR in Cellular Energy Homeostasis and Drug Targets

(2011) Ken Inoki et al.   Annual Review of Pharmacology and Toxicology

LKB1 loss of function studied in vivo

(2011) Boris Y. Shorning et al.   FEBS LETTERS

MicroRNAs Modulate Schwann Cell Response to Nerve Injury by Reinforcing Transcriptional Silencing of Dedifferentiation-Related Genes

(2011) A. Viader et al.   JOURNAL OF NEUROSCIENCE

Schwann Cell Mitochondrial Metabolism Supports Long-Term Axonal Survival and Peripheral Nerve Function

(2011) A. Viader et al.   JOURNAL OF NEUROSCIENCE

Nutrient excess and altered mitochondrial proteome and function contribute to neurodegeneration in diabetes

(2011) Subir K. Roy Chowdhury et al.   MITOCHONDRION

The serine-threonine kinase LKB1 is essential for survival under energetic stress in zebrafish

(2011) Y. U. van der Velden et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sir-two-homolog 2 (Sirt2) modulates peripheral myelination through polarity protein Par-3/atypical protein kinase C (aPKC) signaling

(2011) B. Beirowski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ablation of LKB1 in the heart leads to energy deprivation and impaired cardiac function

(2010) Niels Jessen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Lipid metabolism in myelinating glial cells: lessons from human inherited disorders and mouse models

(2010) Roman Chrast et al.   JOURNAL OF LIPID RESEARCH

RET Signaling Is Required for Survival and Normal Function of Nonpeptidergic Nociceptors

(2010) J. P. Golden et al.   JOURNAL OF NEUROSCIENCE

Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells

(2010) Daisuke Nakada et al.   NATURE

Myelination and support of axonal integrity by glia

(2010) Klaus-Armin Nave   NATURE

Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells

(2010) Boyi Gan et al.   NATURE

Primary cilia regulate mTORC1 activity and cell size through Lkb1

(2010) Christopher Boehlke et al.   NATURE CELL BIOLOGY

Myelination and the trophic support of long axons

(2010) Klaus-Armin Nave   NATURE REVIEWS NEUROSCIENCE

LKB1 and AMP-activated protein kinase control of mTOR signalling and growth

(2009) R. J. Shaw   Acta Physiologica

The regulation and function of mammalian AMPK-related kinases

(2009) N. J. Bright et al.   Acta Physiologica

Automated Lipid Identification and Quantification by Multidimensional Mass Spectrometry-Based Shotgun Lipidomics

(2009) Kui Yang et al.   ANALYTICAL CHEMISTRY

LKB1 Regulates Pancreatic β Cell Size, Polarity, and Function

(2009) Zvi Granot et al.   Cell Metabolism

TAK1 activates AMPK-dependent cytoprotective autophagy in TRAIL-treated epithelial cells

(2009) Griselda Herrero-Martín et al.   EMBO JOURNAL

Human obesity as a heritable disorder of the central control of energy balance

(2009) S O'Rahilly et al.   INTERNATIONAL JOURNAL OF OBESITY

Non-Nuclear WldS Determines Its Neuroprotective Efficacy for Axons and Synapses In Vivo

(2009) B. Beirowski et al.   JOURNAL OF NEUROSCIENCE

A dual leucine kinase–dependent axon self-destruction program promotes Wallerian degeneration

(2009) Bradley R Miller et al.   NATURE NEUROSCIENCE

AMPK in Health and Disease

(2009) Gregory R. Steinberg et al.   PHYSIOLOGICAL REVIEWS

Loss of Lkb1 Provokes Highly Invasive Endometrial Adenocarcinomas

(2008) C. M. Contreras et al.   CANCER RESEARCH

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

(2008) Dana M. Gwinn et al.   MOLECULAR CELL