BET proteins in abnormal metabolism, inflammation, and the breast cancer microenvironment
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Title
BET proteins in abnormal metabolism, inflammation, and the breast cancer microenvironment
Authors
Keywords
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Journal
JOURNAL OF LEUKOCYTE BIOLOGY
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2018-03-02
DOI
10.1002/jlb.5ri0917-380rr
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Note: Only part of the references are listed.- AMPK–Akt Double-Negative Feedback Loop in Breast Cancer Cells Regulates Their Adaptation to Matrix Deprivation
- (2018) Manipa Saha et al. CANCER RESEARCH
- Relationships Among Obesity, Type 2 Diabetes, and Plasma Cytokines in African American Women
- (2017) Gerald V. Denis et al. Obesity
- BET N-terminal bromodomain inhibition selectively blocks Th17 cell differentiation and ameliorates colitis in mice
- (2017) Kalung Cheung et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- BET bromodomain inhibition suppresses innate inflammatory and profibrotic transcriptional networks in heart failure
- (2017) Qiming Duan et al. Science Translational Medicine
- Epigenetic targeting of bromodomain protein BRD4 counteracts cancer cachexia and prolongs survival
- (2017) Marco Segatto et al. Nature Communications
- BET-Bromodomain Inhibitors Engage the Host Immune System and Regulate Expression of the Immune Checkpoint Ligand PD-L1
- (2017) Simon J. Hogg et al. Cell Reports
- Bromodomain and Extra-Terminal Protein Inhibition Attenuates Neutrophil-dominant Allergic Airway Disease
- (2017) Michelle L. Manni et al. Scientific Reports
- BRD4 regulates adiponectin gene induction by recruiting the P-TEFb complex to the transcribed region of the gene
- (2017) Naoko Sakurai et al. Scientific Reports
- BRD4 Regulates Breast Cancer Dissemination through Jagged1/Notch1 Signaling
- (2016) Guillaume Andrieu et al. CANCER RESEARCH
- Calcium-Oxidant Signaling Network Regulates AMP-activated Protein Kinase (AMPK) Activation upon Matrix Deprivation
- (2016) Ananthalakshmy Sundararaman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer
- (2016) Shaokun Shu et al. NATURE
- Epigenomic regulation of oncogenesis by chromatin remodeling
- (2016) R Kumar et al. ONCOGENE
- BET Bromodomain Inhibition Promotes Anti-tumor Immunity by Suppressing PD-L1 Expression
- (2016) Hengrui Zhu et al. Cell Reports
- BET Bromodomain Proteins Brd2, Brd3 and Brd4 Selectively Regulate Metabolic Pathways in the Pancreatic β-Cell
- (2016) Jude T. Deeney et al. PLoS One
- IL17 Promotes Mammary Tumor Progression by Changing the Behavior of Tumor Cells and Eliciting Tumorigenic Neutrophils Recruitment
- (2015) Luciana Benevides et al. CANCER RESEARCH
- Systemic Correlates of White Adipose Tissue Inflammation in Early-Stage Breast Cancer
- (2015) N. M. Iyengar et al. CLINICAL CANCER RESEARCH
- RAS/MAPK Activation Is Associated with Reduced Tumor-Infiltrating Lymphocytes in Triple-Negative Breast Cancer: Therapeutic Cooperation Between MEK and PD-1/PD-L1 Immune Checkpoint Inhibitors
- (2015) S. Loi et al. CLINICAL CANCER RESEARCH
- Nutrition Transition and the Global Diabetes Epidemic
- (2015) Barry M. Popkin Current Diabetes Reports
- Adipose Tissue–Derived Stem Cells From Obese Subjects Contribute to Inflammation and Reduced Insulin Response in Adipocytes Through Differential Regulation of the Th1/Th17 Balance and Monocyte Activation
- (2015) Assia Eljaafari et al. DIABETES
- Potentiated DNA Damage Response in Circulating Breast Tumor Cells Confers Resistance to Chemotherapy
- (2015) Chang Gong et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Interleukin-17 Could Promote Breast Cancer Progression at Several Stages of the Disease
- (2015) Thomas Welte et al. MEDIATORS OF INFLAMMATION
- Th17 cytokines differentiate obesity from obesity-associated type 2 diabetes and promote TNFα production
- (2015) Blanche Ip et al. Obesity
- Immune-mediated antitumor effect by type 2 diabetes drug, metformin
- (2015) Shingo Eikawa et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Systemic neutralization of IL-17A significantly reduces breast cancer associated metastasis in arthritic mice by reducing CXCL12/SDF-1 expression in the metastatic niches
- (2014) Lopamudra Das Roy et al. BMC CANCER
- Expression of programmed death ligand 1 (PD-L1) is associated with poor prognosis in human breast cancer
- (2014) S. Muenst et al. BREAST CANCER RESEARCH AND TREATMENT
- Disrupting the Interaction of BRD4 with Diacetylated Twist Suppresses Tumorigenesis in Basal-like Breast Cancer
- (2014) Jian Shi et al. CANCER CELL
- Metabolic Health Reduces Risk of Obesity-Related Cancer in Framingham Study Adults
- (2014) L. L. Moore et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- An epigenomic approach to therapy for tamoxifen-resistant breast cancer
- (2014) Qin Feng et al. CELL RESEARCH
- T Cell–Derived IL-22 Amplifies IL-1β–Driven Inflammation in Human Adipose Tissue: Relevance to Obesity and Type 2 Diabetes
- (2014) Elise Dalmas et al. DIABETES
- BET bromodomain inhibition suppresses transcriptional responses to cytokine-Jak-STAT signaling in a gene-specific manner in human monocytes
- (2014) Chun Hin Chan et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Adiponectin and leptin in overweight/obese and lean women with polycystic ovary syndrome
- (2014) Chin-I Chen et al. GYNECOLOGICAL ENDOCRINOLOGY
- BET Inhibitor JQ1 Blocks Inflammation and Bone Destruction
- (2014) S. Meng et al. JOURNAL OF DENTAL RESEARCH
- STAT3, STAT4, NFATc1, and CTCF Regulate PD-1 through Multiple Novel Regulatory Regions in Murine T Cells
- (2014) J. W. Austin et al. JOURNAL OF IMMUNOLOGY
- Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancer
- (2014) Irfan A. Asangani et al. NATURE
- Targeting bromodomains: epigenetic readers of lysine acetylation
- (2014) Panagis Filippakopoulos et al. NATURE REVIEWS DRUG DISCOVERY
- Overexpression of SMARCA5 correlates with cell proliferation and migration in breast cancer
- (2014) Quanxiu Jin et al. TUMOR BIOLOGY
- Efficacy of BET Bromodomain Inhibition in Kras-Mutant Non-Small Cell Lung Cancer
- (2013) T. Shimamura et al. CLINICAL CANCER RESEARCH
- Molecular Pathways: Adipose Inflammation as a Mediator of Obesity-Associated Cancer
- (2013) L. R. Howe et al. CLINICAL CANCER RESEARCH
- Breast cancer incidence before and after diagnosis of type 2 diabetes mellitus in women
- (2013) Adedayo A. Onitilo et al. EUROPEAN JOURNAL OF CANCER PREVENTION
- BET bromodomain inhibition suppresses TH17-mediated pathology
- (2013) Deanna A. Mele et al. JOURNAL OF EXPERIMENTAL MEDICINE
- BET Protein Function Is Required for Inflammation: Brd2 Genetic Disruption and BET Inhibitor JQ1 Impair Mouse Macrophage Inflammatory Responses
- (2013) A. C. Belkina et al. JOURNAL OF IMMUNOLOGY
- Increased PD-1 on CD4+CD28− T cell and soluble PD-1 ligand-1 in patients with T2DM: Association with atherosclerotic macrovascular diseases
- (2013) Bimin Shi et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Metformin reverses multidrug resistance and epithelial–mesenchymal transition (EMT) via activating AMP-activated protein kinase (AMPK) in human breast cancer cells
- (2013) Chen Qu et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Phospho Switch Triggers Brd4 Chromatin Binding and Activator Recruitment for Gene-Specific Targeting
- (2013) Shwu-Yuan Wu et al. MOLECULAR CELL
- Brd2 Inhibits Adipogenesis via the ERK1/2 Signaling Pathway in 3T3-L1 Adipocytes
- (2013) Kun Zang et al. PLoS One
- B cells promote inflammation in obesity and type 2 diabetes through regulation of T-cell function and an inflammatory cytokine profile
- (2013) J. DeFuria et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Targeting MYCN in Neuroblastoma by BET Bromodomain Inhibition
- (2013) Alexandre Puissant et al. Cancer Discovery
- BET bromodomain inhibition targets both c-Myc and IL7R in high-risk acute lymphoblastic leukemia
- (2012) C. J. Ott et al. BLOOD
- Mortality After Incident Cancer in People With and Without Type 2 Diabetes: Impact of metformin on survival
- (2012) C. J. Currie et al. DIABETES CARE
- Notch signaling regulates PD-1 expression during CD8+ T-cell activation
- (2012) Mélissa Mathieu et al. IMMUNOLOGY AND CELL BIOLOGY
- Down-regulation of NF-κB Transcriptional Activity in HIV-associated Kidney Disease by BRD4 Inhibition
- (2012) Guangtao Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress
- (2012) Sang-Min Jeon et al. NATURE
- Time use and physical activity: a shift away from movement across the globe
- (2012) S. W. Ng et al. Obesity Reviews
- Colocalization of Inflammatory Response with B7-H1 Expression in Human Melanocytic Lesions Supports an Adaptive Resistance Mechanism of Immune Escape
- (2012) J. M. Taube et al. Science Translational Medicine
- Inflammation and Increased Aromatase Expression Occur in the Breast Tissue of Obese Women with Breast Cancer
- (2011) Patrick G. Morris et al. Cancer Prevention Research
- BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc
- (2011) Jake E. Delmore et al. CELL
- Cellular and molecular mechanisms of metformin: an overview
- (2011) Benoit Viollet et al. CLINICAL SCIENCE
- The imbalance of Th17/Th1/Tregs in patients with type 2 diabetes: relationship with metabolic factors and complications
- (2011) Chun Zeng et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Structural Basis and Specificity of Acetylated Transcription Factor GATA1 Recognition by BET Family Bromodomain Protein Brd3
- (2011) R. Gamsjaeger et al. MOLECULAR AND CELLULAR BIOLOGY
- The Brd4 Extraterminal Domain Confers Transcription Activation Independent of pTEFb by Recruiting Multiple Proteins, Including NSD3
- (2011) S. Rahman et al. MOLECULAR AND CELLULAR BIOLOGY
- RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
- (2011) Johannes Zuber et al. NATURE
- Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia
- (2011) Mark A. Dawson et al. NATURE
- Targeting MYC dependence in cancer by inhibiting BET bromodomains
- (2011) J. A. Mertz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Bromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genes
- (2011) J. M. Lamonica et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion
- (2011) D. Iliopoulos et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Insulin-sensitive obesity
- (2010) Nora Klöting et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Immunity, Inflammation, and Cancer
- (2010) Sergei I. Grivennikov et al. CELL
- Prevalence, Metabolic Features, and Prognosis of Metabolically Healthy Obese Italian Individuals: The Cremona Study
- (2010) G. Calori et al. DIABETES CARE
- An emerging role for bromodomain-containing proteins in chromatin regulation and transcriptional control of adipogenesis
- (2010) Gerald V. Denis et al. FEBS LETTERS
- Elevated Proinflammatory Cytokine Production by a Skewed T Cell Compartment Requires Monocytes and Promotes Inflammation in Type 2 Diabetes
- (2010) M. Jagannathan-Bogdan et al. JOURNAL OF IMMUNOLOGY
- Suppression of inflammation by a synthetic histone mimic
- (2010) Edwige Nicodeme et al. NATURE
- Selective inhibition of BET bromodomains
- (2010) Panagis Filippakopoulos et al. NATURE
- Brd2disruption in mice causes severe obesity without Type 2 diabetes
- (2009) Fangnian Wang et al. BIOCHEMICAL JOURNAL
- Tumor antigen-specific CD8 T cells infiltrating the tumor express high levels of PD-1 and are functionally impaired
- (2009) M. Ahmadzadeh et al. BLOOD
- Correlation of the leptin:adiponectin ratio with measures of insulin resistance in non-diabetic individuals
- (2009) F. M. Finucane et al. DIABETOLOGIA
- Metformin and Pathologic Complete Responses to Neoadjuvant Chemotherapy in Diabetic Patients With Breast Cancer
- (2009) Sao Jiralerspong et al. JOURNAL OF CLINICAL ONCOLOGY
- Interleukin-6 induces an epithelial–mesenchymal transition phenotype in human breast cancer cells
- (2009) N J Sullivan et al. ONCOGENE
- Interleukin 6 secreted from adipose stromal cells promotes migration and invasion of breast cancer cells
- (2009) M Walter et al. ONCOGENE
- Adipose Macrophage Infiltration Is Associated With Insulin Resistance and Vascular Endothelial Dysfunction in Obese Subjects
- (2008) Caroline M. Apovian et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- STAT3 can be activated through paracrine signaling in breast epithelial cells
- (2008) Jacqueline C Lieblein et al. BMC CANCER
- Transforming Growth Factor Subverts the Immune System into Directly Promoting Tumor Growth through Interleukin-17
- (2008) J.-S. Nam et al. CANCER RESEARCH
- Targeting AMPK: A new therapeutic opportunity in breast cancer
- (2008) Sirwan M. Hadad et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- Insulin in the Adjuvant Breast Cancer Setting: A Novel Therapeutic Target for Lifestyle and Pharmacologic Interventions?
- (2008) Pamela J. Goodwin JOURNAL OF CLINICAL ONCOLOGY
- Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies
- (2008) Andrew G Renehan et al. LANCET
- Brd4 Coactivates Transcriptional Activation of NF- B via Specific Binding to Acetylated RelA
- (2008) B. Huang et al. MOLECULAR AND CELLULAR BIOLOGY
- The Double Bromodomain Proteins Brd2 and Brd3 Couple Histone Acetylation to Transcription
- (2008) Gary LeRoy et al. MOLECULAR CELL
- Direct regulation of TWIST by HIF-1α promotes metastasis
- (2008) Muh-Hwa Yang et al. NATURE CELL BIOLOGY
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