Inflammatory Monocytes Drive Influenza A Virus–Mediated Lung Injury in Juvenile Mice

Inhibition of the NOD-Like Receptor Protein 3 Inflammasome Is Protective in Juvenile Influenza A Virus Infection

(2017) Bria M. Coates et al.   Frontiers in Immunology

NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria

(2016) Zhenyu Zhong et al.   CELL

Men and mice: Relating their ages

(2016) Sulagna Dutta et al.   LIFE SCIENCES

Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition

(2016) Michelle D. Tate et al.   Scientific Reports

RNase L Activates the NLRP3 Inflammasome during Viral Infections

(2015) Arindam Chakrabarti et al.   Cell Host & Microbe

Influenza virus-induced lung injury: pathogenesis and implications for treatment

(2015) Susanne Herold et al.   EUROPEAN RESPIRATORY JOURNAL

Alveolar macrophage–derived type I interferons orchestrate innate immunity to RSV through recruitment of antiviral monocytes

(2015) Michelle Goritzka et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Vimentin regulates activation of the NLRP3 inflammasome

(2015) Gimena dos Santos et al.   Nature Communications

Influenza A Virus Infection, Innate Immunity, and Childhood

(2015) Bria M. Coates et al.   JAMA Pediatrics

Mucosal Immune Responses Predict Clinical Outcomes during Influenza Infection Independently of Age and Viral Load

(2014) Christine M. Oshansky et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

CCR2+ Monocyte-Derived Dendritic Cells and Exudate Macrophages Produce Influenza-Induced Pulmonary Immune Pathology and Mortality

(2014) K. L. Lin et al.   JOURNAL OF IMMUNOLOGY

Colony-Stimulating Factor-1 Signaling Suppresses Renal Crystal Formation

(2014) K. Taguchi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Pathogenic potential of interferon αβ in acute influenza infection

(2014) Sophia Davidson et al.   Nature Communications

Flow Cytometric Analysis of Macrophages and Dendritic Cell Subsets in the Mouse Lung

(2013) Alexander V. Misharin et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The Burden of Influenza in Young Children, 2004-2009

(2013) K. A. Poehling et al.   PEDIATRICS

Activation of the NLRP3 Inflammasome by IAV Virulence Protein PB1-F2 Contributes to Severe Pathophysiology and Disease

(2013) Julie L. McAuley et al.   PLoS Pathogens

Innate Immune Function and Mortality in Critically Ill Children With Influenza

(2012) Mark W. Hall et al.   CRITICAL CARE MEDICINE

Influenza viral load and rapid influenza diagnostic tests in children and adults

(2012) Michimaru Hara et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis

(2012) Simon Yona et al.   IMMUNITY

Longitudinal Study of Influenza Molecular Viral Shedding in Hutterite Communities

(2012) M. Loeb et al.   JOURNAL OF INFECTIOUS DISEASES

Estimated global mortality associated with the first 12 months of 2009 pandemic influenza A H1N1 virus circulation: a modelling study

(2012) Fatimah S Dawood et al.   LANCET INFECTIOUS DISEASES

Evasion of Influenza A Viruses from Innate and Adaptive Immune Responses

(2012) Carolien E. van de Sandt et al.   Viruses-Basel

A novel role for matrix metalloproteinase-8 in sepsis*

(2011) Patrick D. Solan et al.   CRITICAL CARE MEDICINE

Cutting Edge: Reactive Oxygen Species Inhibitors Block Priming, but Not Activation, of the NLRP3 Inflammasome

(2011) F. Bauernfeind et al.   JOURNAL OF IMMUNOLOGY

Global burden of respiratory infections due to seasonal influenza in young children: a systematic review and meta-analysis

(2011) Harish Nair et al.   LANCET

Cytokine response in pediatric patients with pandemic influenza H1N1 2009 virus infection and pneumonia: Comparison with pediatric pneumonia without H1N1 2009 infection

(2011) Yeo Hyang Kim et al.   PEDIATRIC PULMONOLOGY

Age-Dependent Maturation of Toll-Like Receptor-Mediated Cytokine Responses in Gambian Infants

(2011) Sarah Burl et al.   PLoS One

Age-related sensitivity and pathological differences in infections by 2009 pandemic influenza A (H1N1) virus

(2011) Shihui Sun et al.   Virology Journal

Type I Interferon Signaling Regulates Ly6Chi Monocytes and Neutrophils during Acute Viral Pneumonia in Mice

(2011) Sang-Uk Seo et al.   PLoS Pathogens

Influenza virus activates inflammasomes via its intracellular M2 ion channel

(2010) Takeshi Ichinohe et al.   NATURE IMMUNOLOGY

Comparative Epidemiology of Pandemic and Seasonal Influenza A in Households

(2010) Benjamin J. Cowling et al.   NEW ENGLAND JOURNAL OF MEDICINE

Ontogeny of Toll-Like Receptor Mediated Cytokine Responses of Human Blood Mononuclear Cells

(2010) Nathan P. Corbett et al.   PLoS One

GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists

(2009) Eran Eden et al.   BMC BIOINFORMATICS

Skewed pattern of Toll-like receptor 4-mediated cytokine production in human neonatal blood: Low LPS-induced IL-12p70 and high IL-10 persist throughout the first month of life

(2009) M.E. Belderbos et al.   CLINICAL IMMUNOLOGY

The NLRP3 Inflammasome Mediates In Vivo Innate Immunity to Influenza A Virus through Recognition of Viral RNA

(2009) Irving C. Allen et al.   IMMUNITY

The Intracellular Sensor NLRP3 Mediates Key Innate and Healing Responses to Influenza A Virus via the Regulation of Caspase-1

(2009) Paul G. Thomas et al.   IMMUNITY

Inflammasome recognition of influenza virus is essential for adaptive immune responses

(2009) Takeshi Ichinohe et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Regulation of Inflammatory Monocyte/Macrophage Recruitment from the Bone Marrow during Murine Cytomegalovirus Infection: Role for Type I Interferons in Localized Induction of CCR2 Ligands

(2009) M. J. Crane et al.   JOURNAL OF IMMUNOLOGY

Neonatal Innate TLR-Mediated Responses Are Distinct from Those of Adults

(2009) T. R. Kollmann et al.   JOURNAL OF IMMUNOLOGY

Developmental Biology of the Innate Immune Response: Implications for Neonatal and Infant Vaccine Development

(2009) Victoria Jane Philbin et al.   PEDIATRIC RESEARCH

Lung epithelial apoptosis in influenza virus pneumonia: the role of macrophage-expressed TNF-related apoptosis-inducing ligand

(2008) Susanne Herold et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Severe seasonal influenza in ferrets correlates with reduced interferon and increased IL-6 induction

(2008) Nicholas Svitek et al.   VIROLOGY