ExacerbatedStaphylococcus aureusFoot Infections in Obese/Diabetic Mice Are Associated with Impaired Germinal Center Reactions, Ig Class Switching, and Humoral Immunity

Metabolic Regulation of the Immune Humoral Response

(2017) Mark Boothby et al.   IMMUNITY

Role of innate and adaptive immunity in obesity-associated metabolic disease

(2017) Tracey McLaughlin et al.   JOURNAL OF CLINICAL INVESTIGATION

B Cell Activity Is Impaired in Human and Mouse Obesity and Is Responsive to an Essential Fatty Acid upon Murine Influenza Infection

(2017) Rasagna Kosaraju et al.   JOURNAL OF IMMUNOLOGY

A Perfect Storm: Increased Colonization and Failure of Vaccination Leads to Severe Secondary Bacterial Infection in Influenza Virus-Infected Obese Mice

(2017) Erik A. Karlsson et al.   mBio

N-3 polyunsaturated fatty acids modulate B cell activity in pre-clinical models: Implications for the immune response to infections

(2016) Jarrett Whelan et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Germinal Center B Cell Dynamics

(2016) Luka Mesin et al.   IMMUNITY

Obesity-associated Inflammation Induces microRNA-155 Expression in Adipocytes and Adipose Tissue: Outcome on Adipocyte Function

(2016) Esma Karkeni et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Neutrophil functions in morbidly obese subjects

(2015) E. Brotfain et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Adipose Tissue–Derived Stem Cells From Obese Subjects Contribute to Inflammation and Reduced Insulin Response in Adipocytes Through Differential Regulation of the Th1/Th17 Balance and Monocyte Activation

(2015) Assia Eljaafari et al.   DIABETES

New Piece in the Jigsaw Puzzle: Adipose Tissue–Derived Stem Cells From Obese Subjects Drive Th17 Polarization

(2015) Balázs Csóka et al.   DIABETES

A Humoral Immune Defect Distinguishes the Response to Staphylococcus aureus Infections in Mice with Obesity and Type 2 Diabetes from That in Mice with Type 1 Diabetes

(2015) Christopher W. Farnsworth et al.   INFECTION AND IMMUNITY

MicroRNAs miR-155 and miR-16 Decrease AID and E47 in B Cells from Elderly Individuals

(2015) Daniela Frasca et al.   JOURNAL OF IMMUNOLOGY

Th17 cytokines differentiate obesity from obesity-associated type 2 diabetes and promote TNFα production

(2015) Blanche Ip et al.   Obesity

Epigenetics of Peripheral B-Cell Differentiation and the Antibody Response

(2015) Hong Zan et al.   Frontiers in Immunology

B cells promote inflammation in obesity and type 2 diabetes through regulation of T-cell function and an inflammatory cytokine profile

(2013) J. DeFuria et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Populations at risk for severe or complicated influenza illness: systematic review and meta-analysis

(2013) D. Mertz et al.   BMJ-British Medical Journal

Insulin Treatment Directly Restores Neutrophil Phagocytosis and Bactericidal Activity in Diabetic Mice and Thereby Improves Surgical Site Staphylococcus aureus Infection

(2012) Hidekazu Yano et al.   INFECTION AND IMMUNITY

Obesity and the risk and outcome of infection

(2012) R Huttunen et al.   INTERNATIONAL JOURNAL OF OBESITY

Obesity, Diabetes, and Preoperative Hyperglycemia as Predictors of Periprosthetic Joint Infection

(2012) Esa Jämsen et al.   JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME

CD23+CD21highCD1dhigh B Cells in Inflamed Lymph Nodes Are a Locally Differentiated Population with Increased Antigen Capture and Activation Potential

(2012) S. Moshkani et al.   JOURNAL OF IMMUNOLOGY

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

Inflammatory Mechanisms in Obesity

(2011) Margaret F. Gregor et al.   Annual Review of Immunology

SHRiMP2: Sensitive yet Practical Short Read Mapping

(2011) Matei David et al.   BIOINFORMATICS

Obesity is associated with impaired immune response to influenza vaccination in humans

(2011) P A Sheridan et al.   INTERNATIONAL JOURNAL OF OBESITY

A Molecular Mechanism for TNF- -Mediated Downregulation of B Cell Responses

(2011) D. Frasca et al.   JOURNAL OF IMMUNOLOGY

B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies

(2011) Daniel A Winer et al.   NATURE MEDICINE

Expanded CD23+/CD21hi B Cells in Inflamed Lymph Nodes Are Associated with the Onset of Inflammatory-Erosive Arthritis in TNF-Transgenic Mice and Are Targets of Anti-CD20 Therapy

(2010) J. Li et al.   JOURNAL OF IMMUNOLOGY

Diabetic Mice Display a Delayed Adaptive Immune Response to Mycobacterium tuberculosis

(2010) T. Vallerskog et al.   JOURNAL OF IMMUNOLOGY

Proinflammatory T helper type 17 cells are effective B-cell helpers

(2010) M. Mitsdoerffer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Signaling mechanisms involved in altered function of macrophages from diet-induced obese mice affect immune responses

(2009) Q. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Obese Diabetic Patients are at Substantial Risk for Deep Infection after Primary TKA

(2008) Michelle M. Dowsey et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

MicroRNA-155 Is a Negative Regulator of Activation-Induced Cytidine Deaminase

(2008) Grace Teng et al.   IMMUNITY

Defects in Innate Immunity Predispose C57BL/6J-Leprdb/Leprdb Mice to Infection by Staphylococcus aureus

(2008) S. Park et al.   INFECTION AND IMMUNITY