The Alternative NF-κB Pathway in Regulatory T Cell Homeostasis and Suppressive Function

An NF-κB Transcription-Factor-Dependent Lineage-Specific Transcriptional Program Promotes Regulatory T Cell Identity and Function

(2017) Hyunju Oh et al.   IMMUNITY

IL-17A-Producing Foxp3+ Regulatory T Cells and Human Diseases

(2017) Min Kyung Jung et al.   Immune Network

Compendium of Immune Signatures Identifies Conserved and Species-Specific Biology in Response to Inflammation

(2016) Jernej Godec et al.   IMMUNITY

The NF-κB transcription factor RelA is required for the tolerogenic function of Foxp3+ regulatory T cells

(2016) Nicole Messina et al.   JOURNAL OF AUTOIMMUNITY

Impairment of Mature B Cell Maintenance upon Combined Deletion of the Alternative NF-κB Transcription Factors RELB and NF-κB2 in B Cells

(2016) Nilushi S. De Silva et al.   JOURNAL OF IMMUNOLOGY

Cell intrinsic role of NF-κB-inducing kinase in regulating T cell-mediated immune and autoimmune responses

(2016) Yanchuan Li et al.   Scientific Reports

IKKα is required for the homeostasis of regulatory T cells and for the expansion of both regulatory and effector CD4 T cells

(2015) Xin Chen et al.   FASEB JOURNAL

Autosomal-dominant B-cell deficiency with alopecia due to a mutation in NFKB2 that results in nonprocessable p100

(2014) C. E. Lee et al.   BLOOD

The adaptor TRAF3 restrains the lineage determination of thymic regulatory T cells by modulating signaling via the receptor for IL-2

(2014) Zuoan Yi et al.   NATURE IMMUNOLOGY

The role of IL-17-producing Foxp3+ CD4+ T cells in inflammatory bowel disease and colon cancer

(2013) Lequn Li et al.   CLINICAL IMMUNOLOGY

Large-scale gene function analysis with the PANTHER classification system

(2013) Huaiyu Mi et al.   Nature Protocols

Cell-Intrinsic Role for NF-kappa B-Inducing Kinase in Peripheral Maintenance but Not Thymic Development of Foxp3+ Regulatory T Cells in Mice

(2013) Susan E. Murray   PLoS One

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

The noncanonical NF-κB pathway

(2012) Shao-Cong Sun   IMMUNOLOGICAL REVIEWS

Balance between NF- B p100 and p52 Regulates T Cell Costimulation Dependence

(2012) M. L. Giardino Torchia et al.   JOURNAL OF IMMUNOLOGY

p100 Deficiency Is Insufficient for Full Activation of the Alternative NF-κB Pathway: TNF Cooperates with p52-RelB in Target Gene Transcription

(2012) Agnes Lovas et al.   PLoS One

Interleukin-12 Converts Foxp3+ Regulatory T Cells to Interferon–γ-Producing Foxp3+ T Cells That Inhibit Colitis

(2011) Ting Feng et al.   GASTROENTEROLOGY

NF-κB–inducing kinase plays an essential T cell–intrinsic role in graft-versus-host disease and lethal autoimmunity in mice

(2011) Susan E. Murray et al.   JOURNAL OF CLINICAL INVESTIGATION

Crosstalk in NF-κB signaling pathways

(2011) Andrea Oeckinghaus et al.   NATURE IMMUNOLOGY

c-Rel Controls Multiple Discrete Steps in the Thymic Development of Foxp3+ CD4 Regulatory T Cells

(2011) George Grigoriadis et al.   PLoS One

c-Rel but not NF-κB1 is important for T regulatory cell development

(2010) Elissa K. Deenick et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

c-Rel is crucial for the induction of Foxp3+regulatory CD4+T cells but not TH17 cells

(2010) Alexander Visekruna et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Cutting Edge: CD28 and c-Rel-Dependent Pathways Initiate Regulatory T Cell Development

(2010) K. B. Vang et al.   JOURNAL OF IMMUNOLOGY

Increased Th17 cells are accompanied by FoxP3+ Treg cell accumulation and correlated with psoriasis disease severity

(2009) Li Zhang et al.   CLINICAL IMMUNOLOGY

Nuclear Factor-κB Modulates Regulatory T Cell Development by Directly Regulating Expression of Foxp3 Transcription Factor

(2009) Meixiao Long et al.   IMMUNITY

Development of Foxp3+ Regulatory T Cells Is Driven by the c-Rel Enhanceosome

(2009) Qingguo Ruan et al.   IMMUNITY

c-Rel is required for the development of thymic Foxp3+CD4 regulatory T cells

(2009) Iwao Isomura et al.   JOURNAL OF EXPERIMENTAL MEDICINE

GITR Triggering Induces Expansion of Both Effector and Regulatory CD4+ T Cells In Vivo

(2009) R. W. van Olffen et al.   JOURNAL OF IMMUNOLOGY

Roles of the NF- B Pathway in Lymphocyte Development and Function

(2009) S. Gerondakis et al.   Cold Spring Harbor Perspectives in Biology

Shared Principles in NF-κB Signaling

(2008) Matthew S. Hayden et al.   CELL

Regulatory T Cells and Immune Tolerance

(2008) Shimon Sakaguchi et al.   CELL

The Foxp3+ regulatory T cell: a jack of all trades, master of regulation

(2008) Qizhi Tang et al.   NATURE IMMUNOLOGY

CTLA-4 Control over Foxp3+ Regulatory T Cell Function

(2008) K. Wing et al.   SCIENCE

The roles of the classical and alternative nuclear factor-kappaB pathways: potential implications for autoimmunity and rheumatoid arthritis

(2008) Keith D Brown et al.   ARTHRITIS RESEARCH & THERAPY

Regulatory T Cells: Mechanisms of Differentiation and Function

(2007) Steven Z. Josefowicz et al.   Annual Review of Immunology