An Antigen-Free, Plasmacytoid Dendritic Cell–Targeting Immunotherapy To Bolster Memory CD8+T Cells in Nonhuman Primates

Mapping the human DC lineage through the integration of high-dimensional techniques

(2017) Peter See et al.   SCIENCE

Species-dependent role of type I IFNs and IL-12 in the CTL response induced by humanized CpG complexed with β-glucan

(2016) Kouji Kobiyama et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Adaptive immunity in HBV infection

(2016) Antonio Bertoletti et al.   JOURNAL OF HEPATOLOGY

Circulating nano-particulate TLR9 agonist scouts out tumor microenvironment to release immunogenic dead tumor cells

(2016) Yuji Kitahata et al.   Oncotarget

Quality and quantity of T FH cells are critical for broad antibody development in SHIV AD8 infection

(2015) Takuya Yamamoto et al.   Science Translational Medicine

The Chemokine System in Innate Immunity

(2015) Caroline L. Sokol et al.   Cold Spring Harbor Perspectives in Biology

Interferon-Stimulated Genes: A Complex Web of Host Defenses

(2014) William M. Schneider et al.   Annual Review of Immunology

Nonagonistic Dectin-1 ligand transforms CpG into a multitask nanoparticulate TLR9 agonist

(2014) K. Kobiyama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TLR9 adjuvants enhance immunogenicity and protective efficacy of the SE36/AHG malaria vaccine in nonhuman primate models

(2013) Takahiro Tougan et al.   Human Vaccines & Immunotherapeutics

Distinct TLR adjuvants differentially stimulate systemic and local innate immune responses in nonhuman primates

(2012) M. Kwissa et al.   BLOOD

Safety and Immunogenicity of Vaccination With MART-1 (26–35, 27L), gp100 (209–217, 210M), and Tyrosinase (368–376, 370D) In Adjuvant With PF-3512676 and GM-CSF In Metastatic Melanoma

(2012) Ahmad A. Tarhini et al.   JOURNAL OF IMMUNOTHERAPY

Virus Inhibition Activity of Effector Memory CD8+ T Cells Determines Simian Immunodeficiency Virus Load in Vaccinated Monkeys after Vaccine Breakthrough Infection

(2012) T. Yamamoto et al.   JOURNAL OF VIROLOGY

IL-12 family cytokines: immunological playmakers

(2012) Dario A A Vignali et al.   NATURE IMMUNOLOGY

Phase 1 Study in Malaria Naïve Adults of BSAM2/Alhydrogel®+CPG 7909, a Blood Stage Vaccine against P. falciparum Malaria

(2012) Ruth D. Ellis et al.   PLoS One

Demonstration of safety and enhanced seroprotection against hepatitis B with investigational HBsAg-1018 ISS vaccine compared to a licensed hepatitis B vaccine

(2012) Benjamin P. Sablan et al.   VACCINE

Comparison of safety and immunogenicity of two doses of investigational hepatitis B virus surface antigen co-administered with an immunostimulatory phosphorothioate oligodeoxyribonucleotide and three doses of a licensed hepatitis B vaccine in healthy adults 18–55 years of age

(2012) Scott A. Halperin et al.   VACCINE

A phase III randomized study of gemcitabine and cisplatin with or without PF-3512676 (TLR9 agonist) as first-line treatment of advanced non-small-cell lung cancer

(2011) C. Manegold et al.   ANNALS OF ONCOLOGY

Vaccination-induced functional competence of circulating human tumor-specific CD8 T-cells

(2011) Petra Baumgaertner et al.   INTERNATIONAL JOURNAL OF CANCER

Impact on Malaria Parasite Multiplication Rates in Infected Volunteers of the Protein-in-Adjuvant Vaccine AMA1-C1/Alhydrogel+CPG 7909

(2011) Christopher J. A. Duncan et al.   PLoS One

Monocyte trafficking in acute and chronic inflammation

(2011) Molly A. Ingersoll et al.   TRENDS IN IMMUNOLOGY

Efficient In vivo Priming by Vaccination with Recombinant NY-ESO-1 Protein and CpG in Antigen Naive Prostate Cancer Patients

(2010) J. Karbach et al.   CLINICAL CANCER RESEARCH

Vaccine Adjuvants: Putting Innate Immunity to Work

(2010) Robert L. Coffman et al.   IMMUNITY

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

TLR-based immune adjuvants

(2010) Folkert Steinhagen et al.   VACCINE

Immunotherapeutic applications of CpG oligodeoxynucleotide TLR9 agonists

(2009) Jörg Vollmer et al.   ADVANCED DRUG DELIVERY REVIEWS

The TLR9 Ligand CpG Promotes the Acquisition of Plasmodium falciparum-Specific Memory B Cells in Malaria-Naive Individuals

(2009) P. D. Crompton et al.   JOURNAL OF IMMUNOLOGY

A Phase 1 study of the blood-stage malaria vaccine candidate AMA1-C1/Alhydrogel® with CPG 7909, using two different formulations and dosing intervals

(2009) Ruth D. Ellis et al.   VACCINE

Dendritic Cells In Vivo: A Key Target for a New Vaccine Science

(2008) Ralph M. Steinman   IMMUNITY