NOD-like receptor X1 functions as a tumor suppressor by inhibiting epithelial-mesenchymal transition and inducing aging in hepatocellular carcinoma cells

Actin cytoskeleton remodeling drives epithelial-mesenchymal transition for hepatoma invasion and metastasis in mice

(2018) Jei-Ming Peng et al.   HEPATOLOGY

Cytoplasmic localization of the cell polarity factor scribble supports liver tumor formation and tumor cell invasiveness

(2018) Shan Wan et al.   HEPATOLOGY

Telomere length and reactive oxygen species levels are positively associated with a high risk of mortality and recurrence in hepatocellular carcinoma

(2018) Eunkyong Ko et al.   HEPATOLOGY

β-catenin deficiency in hepatocytes aggravates hepatocarcinogenesis driven by oncogenic β-catenin and MET

(2018) Yan Liang et al.   HEPATOLOGY

Percutaneous treatment of hepatocellular carcinoma: State of the art and innovations

(2018) Jean-Charles Nault et al.   JOURNAL OF HEPATOLOGY

Gut roundtable meeting paper: selected recent advances in hepatocellular carcinoma

(2017) Alexander Gerbes et al.   GUT

Patients with early recurrence of hepatocellular carcinoma have poor prognosis

(2017) Tomoki Kobayashi et al.   Hepatobiliary & Pancreatic Diseases International

Human hepatocellular carcinomas with a periportal phenotype have the lowest potential for early recurrence after curative resection

(2017) Romain Désert et al.   HEPATOLOGY

Calcium-binding protein 39 promotes hepatocellular carcinoma growth and metastasis by activating extracellular signal-regulated kinase signaling pathway

(2017) Lingxi Jiang et al.   HEPATOLOGY

MicroRNA-206 prevents the pathogenesis of hepatocellular carcinoma by modulating expression of met proto-oncogene and cyclin-dependent kinase 6 in mice

(2017) Heng Wu et al.   HEPATOLOGY

Therapies for advanced stage hepatocellular carcinoma with macrovascular invasion or metastatic disease: A systematic review and meta-analysis

(2017) Richard S. Finn et al.   HEPATOLOGY

Substance P increases liver fibrosis by differential changes in senescence of cholangiocytes and hepatic stellate cells

(2017) Ying Wan et al.   HEPATOLOGY

Sodium glucose cotransporter 2 inhibitor canagliflozin attenuates liver cancer cell growth and angiogenic activity by inhibiting glucose uptake

(2017) Kosuke Kaji et al.   INTERNATIONAL JOURNAL OF CANCER

Hepatocellular carcinoma recurrence after direct antiviral agent treatment: A European multicentre study

(2017) Philippe Kolly et al.   JOURNAL OF HEPATOLOGY

NLRX1 Regulates Effector and Metabolic Functions of CD4+T Cells

(2017) Andrew Leber et al.   JOURNAL OF IMMUNOLOGY

NLRC and NLRX gene family mRNA expression and prognostic value in hepatocellular carcinoma

(2017) Xiangkun Wang et al.   Cancer Medicine

Evidence-Based Diagnosis, Staging, and Treatment of Patients With Hepatocellular Carcinoma

(2016) Jordi Bruix et al.   GASTROENTEROLOGY

Hepatocellular carcinoma repression by TNFα-mediated synergistic lethal effect of mitosis defect-induced senescence and cell death sensitization

(2016) Dan Li et al.   HEPATOLOGY

Hippocalcin-like 1 suppresses hepatocellular carcinoma progression by promoting p21Waf/Cip1 stabilization by activating the ERK1/2-MAPK pathway

(2016) Yonglong Zhang et al.   HEPATOLOGY

Epithelial-to-mesenchymal plasticity of cancer stem cells: therapeutic targets in hepatocellular carcinoma

(2016) Aparna Jayachandran et al.   Journal of Hematology & Oncology

NLRX1 attenuates apoptosis and inflammatory responses in myocardial ischemia by inhibiting MAVS-dependent NLRP3 inflammasome activation

(2016) Hongyan Li et al.   MOLECULAR IMMUNOLOGY

EGFR-targeted mAb therapy modulates autophagy in head and neck squamous cell carcinoma through NLRX1–TUFM protein complex

(2016) Y Lei et al.   ONCOGENE

NLRX1 suppresses tumorigenesis and attenuates histiocytic sarcoma through the negative regulation of NF-κB signaling

(2016) Sheryl Coutermarsh-Ott et al.   Oncotarget

NLRX1 Acts as an Epithelial-Intrinsic Tumor Suppressor through the Modulation of TNF-Mediated Proliferation

(2016) Ivan Tattoli et al.   Cell Reports

The Innate Immune Receptor NLRX1 Functions as a Tumor Suppressor by Reducing Colon Tumorigenesis and Key Tumor-Promoting Signals

(2016) A. Alicia Koblansky et al.   Cell Reports

CXCR2/CXCL5 axis contributes to epithelial–mesenchymal transition of HCC cells through activating PI3K/Akt/GSK-3β/Snail signaling

(2015) Shao-Lai Zhou et al.   CANCER LETTERS

microRNA-26a suppresses recruitment of macrophages by down-regulating macrophage colony-stimulating factor expression through the PI3K/Akt pathway in hepatocellular carcinoma

(2015) Zong-Tao Chai et al.   Journal of Hematology & Oncology

The expanding role of NLRs in antiviral immunity

(2013) Christopher Lupfer et al.   IMMUNOLOGICAL REVIEWS

The Nucleotide-binding Leucine-rich Repeat (NLR) Family Member NLRX1 Mediates Protection against Experimental Autoimmune Encephalomyelitis and Represses Macrophage/Microglia-induced Inflammation

(2013) Timothy K. Eitas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Mitochondrial Proteins NLRX1 and TUFM Form a Complex that Regulates Type I Interferon and Autophagy

(2012) Yu Lei et al.   IMMUNITY

Focused Examination of the Intestinal lamina Propria Yields Greater Molecular Insight into Mechanisms Underlying SIV Induced Immune Dysfunction

(2012) Mahesh Mohan et al.   PLoS One

NLRX1 Negatively Regulates TLR-Induced NF-κB Signaling by Targeting TRAF6 and IKK

(2011) Xiaojun Xia et al.   IMMUNITY

NLRX1 Protein Attenuates Inflammatory Responses to Infection by Interfering with the RIG-I-MAVS and TRAF6-NF-κB Signaling Pathways

(2011) Irving C. Allen et al.   IMMUNITY