MicroRNA-206 prevents the pathogenesis of hepatocellular carcinoma by modulating expression of met proto-oncogene and cyclin-dependent kinase 6 in mice

MicroRNA-206 prevents hepatosteatosis and hyperglycemia by facilitating insulin signaling and impairing lipogenesis

(2017) Heng Wu et al.   JOURNAL OF HEPATOLOGY

Regulation of the T-box transcription factor Tbx3 by the tumour suppressor microRNA-206 in breast cancer

(2016) Sumaira Amir et al.   BRITISH JOURNAL OF CANCER

Future of Hepatocellular Carcinoma Incidence in the United States Forecast Through 2030

(2016) Jessica L. Petrick et al.   JOURNAL OF CLINICAL ONCOLOGY

Co-activation of AKT and c-Met triggers rapid hepatocellular carcinoma development via the mTORC1/FASN pathway in mice

(2016) Junjie Hu et al.   Scientific Reports

microRNA-206 attenuates tumor proliferation and migration involving the downregulation of NOTCH3 in colorectal cancer

(2015) XIAO-WEI WANG et al.   ONCOLOGY REPORTS

Distinct anti-oncogenic effect of various microRNAs in different mouse models of liver cancer

(2015) Junyan Tao et al.   Oncotarget

Inhibition of microRNA-24 expression in liver prevents hepatic lipid accumulation and hyperlipidemia

(2014) Raymond Ng et al.   HEPATOLOGY

Tumor-suppressive microRNA-206 as a dual inhibitor of MET and EGFR oncogenic signaling in lung squamous cell carcinoma

(2014) HIROKO MATAKI et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

MicroRNAs in cancer: biomarkers, functions and therapy

(2014) Josie Hayes et al.   TRENDS IN MOLECULAR MEDICINE

Targeting the HGF/c-MET Pathway in Hepatocellular Carcinoma

(2013) L. Goyal et al.   CLINICAL CANCER RESEARCH

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Hepatocellular carcinoma in non-alcoholic fatty liver disease: An emerging menace

(2012) György Baffy et al.   JOURNAL OF HEPATOLOGY

Tivantinib for second-line treatment of advanced hepatocellular carcinoma: a randomised, placebo-controlled phase 2 study

(2012) Armando Santoro et al.   LANCET ONCOLOGY

Targeted Therapies for Hepatocellular Carcinoma

(2011) Augusto Villanueva et al.   GASTROENTEROLOGY

AKT (v-akt murine thymoma viral oncogene homolog 1) and N-Ras (neuroblastoma ras viral oncogene homolog) coactivation in the mouse liver promotes rapid carcinogenesis by way of mTOR (mammalian target of rapamycin complex 1), FOXM1 (forkhead box M1)/SKP2,

(2011) Coral Ho et al.   HEPATOLOGY

Use of target protector morpholinos to analyze the physiological roles of specific miRNA-mRNA pairs in vivo

(2011) Alison A Staton et al.   Nature Protocols

Prognostic markers and putative therapeutic targets for hepatocellular carcinoma

(2010) Maddalena Frau et al.   MOLECULAR ASPECTS OF MEDICINE

Hepatocellular carcinoma: a global view

(2010) Ju Dong Yang et al.   Nature Reviews Gastroenterology & Hepatology

starBase: a database for exploring microRNA–mRNA interaction maps from Argonaute CLIP-Seq and Degradome-Seq data

(2010) Jian-Hua Yang et al.   NUCLEIC ACIDS RESEARCH

Optimized Adeno-Associated Virus (AAV)–Protein Phosphatase-5 Helper Viruses for Efficient Liver Transduction by Single-Stranded AAV Vectors: Therapeutic Expression of Factor IX at Reduced Vector Doses

(2009) Giridhara R. Jayandharan et al.   HUMAN GENE THERAPY

MicroRNA-1/206 Targets c-Metand Inhibits Rhabdomyosarcoma Development

(2009) Dongsheng Yan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-206 Targetsnotch3, Activates Apoptosis, and Inhibits Tumor Cell Migration and Focus Formation

(2009) Guisheng Song et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

miR-206 Expression Is Down-regulated in Estrogen Receptor  -Positive Human Breast Cancer

(2008) N. Kondo et al.   CANCER RESEARCH

Role of Cyclin D1 as a Mediator of c-Met- and  -Catenin-Induced Hepatocarcinogenesis

(2008) M. A. Patil et al.   CANCER RESEARCH

Association of MicroRNA Expression in Hepatocellular Carcinomas with Hepatitis Infection, Cirrhosis, and Patient Survival

(2008) J. Jiang et al.   CLINICAL CANCER RESEARCH

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations

(2008) Yannick Ladeiro et al.   HEPATOLOGY

Molecular targeted therapies in hepatocellular carcinoma

(2008) Josep M. Llovet et al.   HEPATOLOGY