The ins and outs of vesicular monoamine transporters

Shared Molecular Mechanisms of Membrane Transporters

(2016) David Drew et al.   Annual Review of Biochemistry

Emulating proton-induced conformational changes in the vesicular monoamine transporter VMAT2 by mutagenesis

(2016) Dana Yaffe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structure of a LacY–nanobody complex in a periplasmic-open conformation

(2016) Xin Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Relocation of active site carboxylates in major facilitator superfamily multidrug transporter LmrP reveals plasticity in proton interactions

(2016) Asha V. Nair et al.   Scientific Reports

Structural Symmetry in Membrane Proteins

(2015) Lucy R. Forrest   Annual Review of Biophysics

Structural Biology of the Major Facilitator Superfamily Transporters

(2015) Nieng Yan   Annual Review of Biophysics

Molecular insights into proton coupled peptide transport in the PTR family of oligopeptide transporters

(2015) Simon Newstead   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Molecular basis of ligand recognition and transport by glucose transporters

(2015) Dong Deng et al.   NATURE

Structure and mechanism of the mammalian fructose transporter GLUT5

(2015) Norimichi Nomura et al.   NATURE

A chemiosmotic mechanism of symport

(2015) H. Ronald Kaback   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gating Topology of the Proton-Coupled Oligopeptide Symporters

(2015) Philip W. Fowler et al.   STRUCTURE

Outward- and inward-facing structures of a putative bacterial transition-metal transporter with homology to ferroportin

(2015) Reiya Taniguchi et al.   Nature Communications

Functionally Important Carboxyls in a Bacterial Homologue of the Vesicular Monoamine Transporter (VMAT)

(2014) Dana Yaffe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Competition as a Way of Life for H+-Coupled Antiporters

(2014) Shimon Schuldiner   JOURNAL OF MOLECULAR BIOLOGY

Crystal structure of the human glucose transporter GLUT1

(2014) Dong Deng et al.   NATURE

Structure-based mechanism for Na+/melibiose symport by MelB

(2014) Abdul S. Ethayathulla et al.   Nature Communications

Proton-coupled sugar transport in the prototypical major facilitator superfamily protein XylE

(2014) Goragot Wisedchaisri et al.   Nature Communications

Identification of a mammalian vesicular polyamine transporter

(2014) Miki Hiasa et al.   Scientific Reports

Coupling of remote alternating-access transport mechanisms for protons and substrates in the multidrug efflux pump AcrB

(2014) Thomas Eicher et al.   eLife

Relation between sequence and structure in membrane proteins

(2013) Mireia Olivella et al.   BIOINFORMATICS

Identification of Conformationally Sensitive Residues Essential for Inhibition of Vesicular Monoamine Transport by the Noncompetitive Inhibitor Tetrabenazine

(2013) Yelena Ugolev et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural basis for alternating access of a eukaryotic calcium/proton exchanger

(2013) Andrew B. Waight et al.   NATURE

Crystal structure of a nitrate/nitrite exchanger

(2013) Hongjin Zheng et al.   NATURE

Structural basis for the drug extrusion mechanism by a MATE multidrug transporter

(2013) Yoshiki Tanaka et al.   NATURE

Structural insights into H+-coupled multidrug extrusion by a MATE transporter

(2013) Min Lu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Identification of molecular hinge points mediating alternating access in the vesicular monoamine transporter VMAT2

(2013) D. Yaffe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the YajR transporter suggests a transport mechanism based on the conserved motif A

(2013) Daohua Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

(Pseudo-)Symmetrical Transport

(2013) L. R. Forrest   SCIENCE

Structural Basis for the Counter-Transport Mechanism of a H+/Ca2+ Exchanger

(2013) T. Nishizawa et al.   SCIENCE

A Substrate Binding Hinge Domain Is Critical for Transport-related Structural Changes of Organic Cation Transporter 1

(2012) Brigitte Egenberger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Mechanistic Basis for Noncompetitive Ibogaine Inhibition of Serotonin and Dopamine Transporters

(2012) Simon Bulling et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dissection of Mechanistic Principles of a Secondary Multidrug Efflux Protein

(2012) Nir Fluman et al.   MOLECULAR CELL

Crystal structure of a bacterial homologue of glucose transporters GLUT1–4

(2012) Linfeng Sun et al.   NATURE

Dynamics of the L-fucose/H+ symporter revealed by fluorescence spectroscopy

(2012) J. Sugihara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Alternating-Access Mechanism of MFS Transporters Arises from Inverted-Topology Repeats

(2011) Sebastian Radestock et al.   JOURNAL OF MOLECULAR BIOLOGY

SLC6 Neurotransmitter Transporters: Structure, Function, and Regulation

(2011) A. S. Kristensen et al.   PHARMACOLOGICAL REVIEWS

Opening the periplasmic cavity in lactose permease is the limiting step for sugar binding

(2011) I. Smirnova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The structural basis of secondary active transport mechanisms

(2010) Lucy R. Forrest et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Model quality assessment for membrane proteins

(2010) Arjun Ray et al.   BIOINFORMATICS

Directed Evolution Reveals Hidden Properties of VMAT, a Neurotransmitter Transporter

(2009) Yael Gros et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Secondary Multidrug/Proton Antiporter MdfA Tolerates Displacements of an Essential Negatively Charged Side Chain

(2009) Nadejda Sigal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Residues Gating the Periplasmic Pathway of LacY

(2009) Yonggang Zhou et al.   JOURNAL OF MOLECULAR BIOLOGY

The Rocking Bundle: A Mechanism for Ion-Coupled Solute Flux by Symmetrical Transporters

(2009) Lucy R. Forrest et al.   PHYSIOLOGY

Inward-facing conformation of glutamate transporters as revealed by their inverted-topology structural repeats

(2009) T. J. Crisman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ins and Outs of Major Facilitator Superfamily Antiporters

(2008) Christopher J. Law et al.   Annual Review of Microbiology

Mechanism for alternating access in neurotransmitter transporters

(2008) L. R. Forrest et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Opening and closing of the periplasmic gate in lactose permease

(2008) Y. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA