Insights into brown adipose tissue evolution and function from non-model organisms

Uncoupling protein 1 controls reactive oxygen species in brown adipose tissue

(2017) Martin Jastroch   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genomic evidence reveals a radiation of placental mammals uninterrupted by the KPg boundary

(2017) Liang Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cold adaptation in pigs depends on UCP3 in beige adipocytes

(2017) Jun Lin et al.   Journal of Molecular Cell Biology

Evolution of UCP1 Transcriptional Regulatory Elements Across the Mammalian Phylogeny

(2017) Michael J. Gaudry et al.   Frontiers in Physiology

Inactivation of thermogenic UCP1 as a historical contingency in multiple placental mammal clades

(2017) Michael J. Gaudry et al.   Science Advances

Seasonal changes in brown adipose tissue mitochondria in a mammalian hibernator: from gene expression to function

(2016) Mallory A. Ballinger et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Brown adipose tissue: physiological function and evolutionary significance

(2015) R. Oelkrug et al.   JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMIC AND ENVIRONMENTAL PHYSIOLOGY

Enhanced stability and polyadenylation of select mRNAs support rapid thermogenesis in the brown fat of a hibernator

(2015) Katharine R Grabek et al.   eLife

Genetic disruption of uncoupling protein 1 in mice renders brown adipose tissue a significant source of FGF21 secretion

(2015) Susanne Keipert et al.   Molecular Metabolism

When pigs fly, UCP1 makes heat

(2015) Martin Jastroch et al.   Molecular Metabolism

Brite/beige fat and UCP1 — is it thermogenesis?

(2014) Susanne Keipert et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Effects of reproductive status and high ambient temperatures on the body temperature of a free-ranging basoendotherm

(2014) Danielle L. Levesque et al.   JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMIC AND ENVIRONMENTAL PHYSIOLOGY

Increased homeothermy during reproduction in a basal placental mammal

(2014) D. L. Levesque et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Mammal survival at the Cretaceous-Palaeogene boundary: metabolic homeostasis in prolonged tropical hibernation in tenrecs

(2014) B. G. Lovegrove et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Adaptive thermogenesis in adipocytes: Is beige the new brown?

(2013) J. Wu et al.   GENES & DEVELOPMENT

Mitochondrial uncoupling prevents cold-induced oxidative stress: a case study using UCP1 knockout mice

(2013) A. Stier et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Adipose tissue browning and metabolic health

(2013) Alexander Bartelt et al.   Nature Reviews Endocrinology

Transcriptomic Analysis of Brown Adipose Tissue across the Physiological Extremes of Natural Hibernation

(2013) Marshall Hampton et al.   PLoS One

The Placental Mammal Ancestor and the Post-K-Pg Radiation of Placentals

(2013) M. A. O'Leary et al.   SCIENCE

Brown fat in a protoendothermic mammal fuels eutherian evolution

(2013) Rebecca Oelkrug et al.   Nature Communications

UCP1 in Brite/Beige Adipose Tissue Mitochondria Is Functionally Thermogenic

(2013) Irina G. Shabalina et al.   Cell Reports

Pharmacological and nutritional agents promoting browning of white adipose tissue

(2012) M. Luisa Bonet et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Absence of adaptive nonshivering thermogenesis in a marsupial, the fat-tailed dunnart (Sminthopsis crassicaudata)

(2011) E. T. Polymeropoulos et al.   JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMIC AND ENVIRONMENTAL PHYSIOLOGY

The Regulation and Physiology of Mitochondrial Proton Leak

(2011) Ajit S. Divakaruni et al.   PHYSIOLOGY

Impacts of the Cretaceous Terrestrial Revolution and KPg Extinction on Mammal Diversification

(2011) R. W. Meredith et al.   SCIENCE

Adaptive thermogenesis and thermal conductance in wild-type and UCP1-KO mice

(2010) Carola W. Meyer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Sympathetic and sensory innervation of brown adipose tissue

(2010) T J Bartness et al.   INTERNATIONAL JOURNAL OF OBESITY

Torpor patterns, arousal rates, and temporal organization of torpor entry in wildtype and UCP1-ablated mice

(2010) R. Oelkrug et al.   JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMIC AND ENVIRONMENTAL PHYSIOLOGY

Beige Can Be Slimming

(2010) J. Ishibashi et al.   SCIENCE

Molecular evolution of UCP1 and the evolutionary history of mammalian non-shivering thermogenesis

(2009) David A Hughes et al.   BMC EVOLUTIONARY BIOLOGY

UCP1 Ablation Induces Obesity and Abolishes Diet-Induced Thermogenesis in Mice Exempt from Thermal Stress by Living at Thermoneutrality

(2009) Helena M. Feldmann et al.   Cell Metabolism

Chronic Peroxisome Proliferator-activated Receptor γ (PPARγ) Activation of Epididymally Derived White Adipocyte Cultures Reveals a Population of Thermogenically Competent, UCP1-containing Adipocytes Molecularly Distinct from Classic Brown Adipocytes

(2009) Natasa Petrovic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial uncoupling protein 1 expression in thymocytes

(2008) Alison E. Adams et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Nonshivering thermogenesis protects against defective calcium handling in muscle

(2008) Jan Aydin et al.   FASEB JOURNAL

The effects of fasting and cold exposure on metabolic rate and mitochondrial proton leak in liver and skeletal muscle of an amphibian, the cane toad Bufo marinus

(2008) M. Trzcionka et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

PRDM16 controls a brown fat/skeletal muscle switch

(2008) Patrick Seale et al.   NATURE

Novel reptilian uncoupling proteins: molecular evolution and gene expression during cold acclimation

(2008) T. S Schwartz et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Images of mitochondrial UCP 1 in mouse thymocytes using confocal microscopy

(2007) Alison E. Adams et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Marsupial uncoupling protein 1 sheds light on the evolution of mammalian nonshivering thermogenesis

(2007) M. Jastroch et al.   PHYSIOLOGICAL GENOMICS