Chemerin: a multifaceted adipokine involved in metabolic disorders

Six weeks of combined aerobic and resistance exercise using outdoor exercise machines improves fitness, insulin resistance, and chemerin in the Korean elderly: A pilot randomized controlled trial

(2018) Dong-Il Kim et al.   ARCHIVES OF GERONTOLOGY AND GERIATRICS

The Chemerin Receptor CMKLR1 is a Functional Receptor for Amyloid-β Peptide

(2018) Lei Peng et al.   JOURNAL OF ALZHEIMERS DISEASE

Serum chemerin level during the first trimester of pregnancy and the risk of gestational diabetes mellitus

(2017) Xuezhou Yang et al.   GYNECOLOGICAL ENDOCRINOLOGY

Gax suppresses chemerin/CMKLR1-induced preadipocyte biofunctions through the inhibition of Akt/mTOR and ERK signaling pathways

(2017) Yunqi Jiang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Maternal circulating adipokine profile and insulin resistance in women at high risk of developing gestational diabetes mellitus

(2017) Kym J. Guelfi et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

International Union of Basic and Clinical Pharmacology CIII: Chemerin Receptors CMKLR1 (Chemerin1) and GPR1 (Chemerin2) Nomenclature, Pharmacology, and Function

(2017) Amanda J. Kennedy et al.   PHARMACOLOGICAL REVIEWS

Resolvin E1/E2 ameliorate lipopolysaccharide-induced depression-like behaviors via ChemR23

(2017) Satoshi Deyama et al.   PSYCHOPHARMACOLOGY

Inflammation and the Metabolic Syndrome: The Tissue-Specific Functions of NF-κB

(2017) Leen Catrysse et al.   TRENDS IN CELL BIOLOGY

Chemerin-induced arterial contraction is Gi- and calcium-dependent

(2017) David J. Ferland et al.   VASCULAR PHARMACOLOGY

LDL receptor (LDLR) expression and function in human pancreatic beta cells

(2016) A. Thedrez et al.   ATHEROSCLEROSIS

CMKLR1 deficiency influences glucose tolerance and thermogenesis in mice on high fat diet

(2016) Chen Huang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Adipose Recruitment and Activation of Plasmacytoid Dendritic Cells Fuel Metaflammation

(2016) Amrit Raj Ghosh et al.   DIABETES

Crosstalk between skin inflammation and adipose tissue-derived products: pathogenic evidence linking psoriasis to increased adiposity

(2016) Andrea Chiricozzi et al.   Expert Review of Clinical Immunology

Chemerin activation in human obesity

(2016) Shwu-Shin Chang et al.   Obesity

Chemokine-Like Receptor 1 Is a Novel Wnt Target Gene that Regulates Mesenchymal Stem Cell Differentiation

(2016) Shanmugam Muruganandan et al.   STEM CELLS

Chemerin Elicits Potent Constrictor Actions via Chemokine‐Like Receptor 1 (CMKLR1), not G‐Protein‐Coupled Receptor 1 (GPR1), in Human and Rat Vasculature

(2016) Amanda J. Kennedy et al.   Journal of the American Heart Association

Association of Chemerin and Vascular Endothelial Growth Factor (VEGF) with Diabetic Nephropathy

(2016) Shuhua Lin et al.   MEDICAL SCIENCE MONITOR

Chemerin as an independent predictor of cardiovascular event risk

(2016) Sinan İnci et al.   Therapeutic Advances in Endocrinology and Metabolism

Elevated Plasma Levels of Chemerin in Newly Diagnosed Type 2 Diabetes Mellitus With Hypertension

(2016) Mengliu Yang et al.   JOURNAL OF INVESTIGATIVE MEDICINE

Signaling Properties of Chemerin Receptors CMKLR1, GPR1 and CCRL2

(2016) Olivier De Henau et al.   PLoS One

A neuroendocrine role for chemerin in hypothalamic remodelling and photoperiodic control of energy balance

(2016) Gisela Helfer et al.   Scientific Reports

Chemerin promotes proliferation and migration of vascular smooth muscle and increases mouse blood pressure

(2015) Hidemizu Kunimoto et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Chemerin and prediction of Diabetes mellitus type 2

(2015) Thomas Bobbert et al.   CLINICAL ENDOCRINOLOGY

Chemerin Regulates Crosstalk Between Adipocytes and Vascular Cells Through NoxNovelty and Significance

(2015) Karla Bianca Neves et al.   HYPERTENSION

Exercise-Induced Weight Loss Is More Effective than Dieting for Improving Adipokine Profile, Insulin Resistance, and Inflammation in Obese Men

(2015) Joan Khoo et al.   INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM

Photoperiodic Effects on Seasonal Physiology, Reproductive Status and Hypothalamic Gene Expression in Young Male F344 Rats

(2015) F. M. Tavolaro et al.   JOURNAL OF NEUROENDOCRINOLOGY

CMKLR1 and GPR1 mediate chemerin signaling through the RhoA/ROCK pathway

(2015) Jillian L. Rourke et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Chemerin inhibition of myogenesis and induction of adipogenesis in C2C12 myoblasts

(2015) Hui-Xia Li et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Immunological contributions to adipose tissue homeostasis

(2015) Joanna R. DiSpirito et al.   SEMINARS IN IMMUNOLOGY

Evidence from studies in rodents and in isolated adipocytes that agonists of the chemerin receptor CMKLR1 may be beneficial in the treatment of type 2 diabetes

(2015) Edward T. Wargent et al.   PeerJ

The Expression and Regulation of Chemerin in the Epidermis

(2015) Magdalena Banas et al.   PLoS One

Contrasting effects of cold acclimation versus obesogenic diets on chemerin gene expression in brown and brite adipose tissues

(2014) Ida R. Hansen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Loss of White Adipose Hyperplastic Potential Is Associated with Enhanced Susceptibility to Insulin Resistance

(2014) Soo M. Kim et al.   Cell Metabolism

Activation of SIRT3 by the NAD+ Precursor Nicotinamide Riboside Protects from Noise-Induced Hearing Loss

(2014) Kevin D. Brown et al.   Cell Metabolism

Decreased plasma chemerin levels in women with gestational diabetes mellitus

(2014) K. J. Hare et al.   DIABETIC MEDICINE

On the value of seasonal mammals for identifying mechanisms underlying the control of food intake and body weight

(2014) Francis J.P. Ebling   HORMONES AND BEHAVIOR

Processing, signaling, and physiological function of chemerin

(2014) Andreas Mattern et al.   IUBMB LIFE

The role of adipose tissue immune cells in obesity and low-grade inflammation

(2014) Milos Mraz et al.   JOURNAL OF ENDOCRINOLOGY

Gpr1 is an active chemerin receptor influencing glucose homeostasis in obese mice

(2014) Jillian L Rourke et al.   JOURNAL OF ENDOCRINOLOGY

Endothelial Cell-Derived Chemerin Promotes Dendritic Cell Transmigration

(2014) S. Gonzalvo-Feo et al.   JOURNAL OF IMMUNOLOGY

Chemokine-Like Receptor 1 Deficiency Does Not Affect the Development of Insulin Resistance and Nonalcoholic Fatty Liver Disease in Mice

(2014) Nanda Gruben et al.   PLoS One

Identification of an Adipogenic Niche for Adipose Tissue Remodeling and Restoration

(2013) Yun-Hee Lee et al.   Cell Metabolism

Stat3 Activation Links a C/EBPδ to Myostatin Pathway to Stimulate Loss of Muscle Mass

(2013) Liping Zhang et al.   Cell Metabolism

Chemerin is associated with inflammatory markers and metabolic syndrome phenotypes in hypertension patients

(2013) Ping Gu et al.   CLINICAL AND EXPERIMENTAL HYPERTENSION

Overexpression of chemerin was associated with tumor angiogenesis and poor clinical outcome in squamous cell carcinoma of the oral tongue

(2013) Ning Wang et al.   Clinical Oral Investigations

The hypothalamus and metabolism: integrating signals to control energy and glucose homeostasis

(2013) Anthony P Coll et al.   CURRENT OPINION IN PHARMACOLOGY

Raxregulates hypothalamic tanycyte differentiation and barrier function in mice

(2013) Ana L. Miranda-Angulo et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Expression of chemerin and its receptors in rat testes and its action on testosterone secretion

(2013) Lei Li et al.   JOURNAL OF ENDOCRINOLOGY

ChemR23 knockout mice display mild obesity but no deficit in adipocyte differentiation

(2013) Laurie Rouger et al.   JOURNAL OF ENDOCRINOLOGY

Peripheral chemerin administration modulates hypothalamic control of feeding

(2013) Luigi Brunetti et al.   PEPTIDES

Chemerin gene expression is regulated by food restriction and food restriction–refeeding in rat adipose tissue but not in liver

(2013) Ewa Stelmanska et al.   REGULATORY PEPTIDES

Pioglitazone and metformin are equally effective in reduction of chemerin in patients with type 2 diabetes

(2013) Alireza Esteghamati et al.   Journal of Diabetes Investigation

Diabetes as a complication of adipose tissue dysfunction. Is there a role for potential new biomarkers?

(2012) Katarzyna Bergmann et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Decreased serum chemerin levels in male Japanese patients with type 2 diabetes: sex dimorphism

(2012) Michiko Takahashi et al.   ENDOCRINE JOURNAL

Chemerin inhibits IGF-1-induced progesterone and estradiol secretion in human granulosa cells

(2012) M. Reverchon et al.   HUMAN REPRODUCTION

Chemerin as a Mediator between Obesity and Vascular Inflammation in Children

(2012) Kathrin Landgraf et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Chronic mild restraint stress rats decreased CMKLR1 expression in distinct brain region

(2012) Xiaoyun Guo et al.   NEUROSCIENCE LETTERS

Towards an integrative approach to understanding the role of chemerin in human health and disease

(2012) J. L. Rourke et al.   Obesity Reviews

Inhibitor of Differentiation-3 Mediates High Fat Diet-Induced Visceral Fat Expansion

(2011) Alexis Cutchins et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Chemerin levels are positively correlated with abdominal visceral fat accumulation

(2011) Hyun-Young Shin et al.   CLINICAL ENDOCRINOLOGY

Disruption of the Chemokine-Like Receptor-1 (CMKLR1) Gene Is Associated with Reduced Adiposity and Glucose Intolerance

(2011) Matthew C. Ernst et al.   ENDOCRINOLOGY

Chemerin158K Protein Is the Dominant Chemerin Isoform in Synovial and Cerebrospinal Fluids but Not in Plasma

(2011) Lei Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Chemerin, a Novel Peroxisome Proliferator-activated Receptor γ (PPARγ) Target Gene That Promotes Mesenchymal Stem Cell Adipogenesis

(2011) Shanmugam Muruganandan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adipose tissue remodeling and obesity

(2011) Kai Sun et al.   JOURNAL OF CLINICAL INVESTIGATION

Effects of weight loss and exercise on chemerin serum concentrations and adipose tissue expression in human obesity

(2011) Rima Chakaroun et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

A Better Index of Body Adiposity

(2011) Richard N. Bergman et al.   Obesity

Effects of vaspin, chemerin and omentin-1 on feeding behavior and hypothalamic peptide gene expression in the rat

(2011) Luigi Brunetti et al.   PEPTIDES

Thyroid Hormone Signalling Genes Are Regulated by Photoperiod in the Hypothalamus of F344 Rats

(2011) Alexander W. Ross et al.   PLoS One

Chemerin regulates β-cell function in mice

(2011) Michiko Takahashi et al.   Scientific Reports

Identification of chemerin receptor (ChemR23) in human endothelial cells: Chemerin-induced endothelial angiogenesis

(2010) Jaspreet Kaur et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Expression of Human Chemerin Induces Insulin Resistance in the Skeletal Muscle but Does Not Affect Weight, Lipid Levels, and Atherosclerosis in LDL Receptor Knockout Mice on High-Fat Diet

(2010) M. Becker et al.   DIABETES

Chemerin Exacerbates Glucose Intolerance in Mouse Models of Obesity and Diabetes

(2010) Matthew C. Ernst et al.   ENDOCRINOLOGY

Chemerin Correlates with Markers for Fatty Liver in Morbidly Obese Patients and Strongly Decreases after Weight Loss Induced by Bariatric Surgery

(2010) Henrike Sell et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Chemerin, a Novel Adipokine in the Regulation of Angiogenesis

(2010) Kiymet Bozaoglu et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Chemerin: at the crossroads of inflammation and obesity

(2010) Matthew C. Ernst et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Systemic chemerin is related to inflammation rather than obesity in type 2 diabetes

(2009) Johanna Weigert et al.   CLINICAL ENDOCRINOLOGY

Chemerin Is a Novel Adipocyte-Derived Factor Inducing Insulin Resistance in Primary Human Skeletal Muscle Cells

(2009) Henrike Sell et al.   DIABETES

Chemerin Is Associated with Metabolic Syndrome Phenotypes in a Mexican-American Population

(2009) Kiymet Bozaoglu et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Mouse ChemR23 Is Expressed in Dendritic Cell Subsets and Macrophages, and Mediates an Anti-Inflammatory Activity of Chemerin in a Lung Disease Model

(2009) S. Luangsay et al.   JOURNAL OF IMMUNOLOGY

Obesity and low-grade inflammation: a paediatric perspective

(2009) C. S. Tam et al.   Obesity Reviews

Interleukin-1ß induces the novel adipokine chemerin in adipocytes in vitro

(2009) Susan Kralisch et al.   REGULATORY PEPTIDES

Chemerin enhances insulin signaling and potentiates insulin-stimulated glucose uptake in 3T3-L1 adipocytes

(2008) Michiko Takahashi et al.   FEBS LETTERS

Synthetic chemerin-derived peptides suppress inflammation through ChemR23

(2008) Jenna L. Cash et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mast cell–expressed orphan receptor CCRL2 binds chemerin and is required for optimal induction of IgE-mediated passive cutaneous anaphylaxis

(2008) Brian A. Zabel et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Macrophage-Secreted Factors Promote a Profibrotic Phenotype in Human Preadipocytes

(2008) Mayoura Keophiphath et al.   MOLECULAR ENDOCRINOLOGY

Angiogenesis and obesity

(2007) H. R. Lijnen   CARDIOVASCULAR RESEARCH