Hyaluronan impairs the barrier integrity of brain microvascular endothelial cells through a CD44-dependent pathway

CD44 Transmembrane Receptor and Hyaluronan Regulate Adult Hippocampal Neural Stem Cell Quiescence and Differentiation

(2017) Weiping Su et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Isogenic blood-brain barrier models based on patient-derived stem cells display inter-individual differences in cell maturation and functionality

(2017) Ronak Patel et al.   JOURNAL OF NEUROCHEMISTRY

An isogenic blood-brain barrier model comprising brain endothelial cells, astrocytes, and neurons derived from human induced pluripotent stem cells

(2017) Scott G. Canfield et al.   JOURNAL OF NEUROCHEMISTRY

Huntington’s Disease iPSC-Derived Brain Microvascular Endothelial Cells Reveal WNT-Mediated Angiogenic and Blood-Brain Barrier Deficits

(2017) Ryan G. Lim et al.   Cell Reports

The CD44 ligand hyaluronic acid is elevated in the cerebrospinal fluid of suicide attempters and is associated with increased blood–brain barrier permeability

(2016) F. Ventorp et al.   JOURNAL OF AFFECTIVE DISORDERS

bFGF Protects Against Blood-Brain Barrier Damage Through Junction Protein Regulation via PI3K-Akt-Rac1 Pathway Following Traumatic Brain Injury

(2015) Zhou-Guang Wang et al.   MOLECULAR NEUROBIOLOGY

Increased expression of surface CD44 in hypoxia-DCs skews helper T cells toward a Th2 polarization

(2015) Meixiang Yang et al.   Scientific Reports

Association between plasma levels of hyaluronic acid and functional outcome in acute stroke patients

(2014) Sung-Chun Tang et al.   Journal of Neuroinflammation

A retinoic acid-enhanced, multicellular human blood-brain barrier model derived from stem cell sources

(2014) Ethan S. Lippmann et al.   Scientific Reports

CD44 Deficiency Contributes to Enhanced Experimental Autoimmune Encephalomyelitis

(2013) Kelly M. Flynn et al.   AMERICAN JOURNAL OF PATHOLOGY

CD44 regulates vascular endothelial barrier integrity via a PECAM-1 dependent mechanism

(2013) Kelly M. Flynn et al.   ANGIOGENESIS

Paclitaxel–Hyaluronic NanoConjugates Prolong Overall Survival in a Preclinical Brain Metastases of Breast Cancer Model

(2013) Rajendar K. Mittapalli et al.   MOLECULAR CANCER THERAPEUTICS

Hyaluronan Anchored to Activated CD44 on Central Nervous System Vascular Endothelial Cells Promotes Lymphocyte Extravasation in Experimental Autoimmune Encephalomyelitis

(2012) Clayton W. Winkler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hyaluronic Acid Receptor CD44 Deficiency Is Associated with Decreased Cryptococcus neoformansBrain Infection

(2012) Ambrose Jong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells

(2012) Ethan S Lippmann et al.   NATURE BIOTECHNOLOGY

Blood-brain barrier modeling with co-cultured neural progenitor cell-derived astrocytes and neurons

(2011) Ethan S. Lippmann et al.   JOURNAL OF NEUROCHEMISTRY

Co-expression of CD147 (EMMPRIN), CD44v3-10, MDR1 and monocarboxylate transporters is associated with prostate cancer drug resistance and progression

(2010) J Hao et al.   BRITISH JOURNAL OF CANCER

Hyaluronan blocks oligodendrocyte progenitor maturation and remyelination through TLR2

(2010) J. A. Sloane et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coexpression of invasive markers (uPA, CD44) and multiple drug-resistance proteins (MDR1, MRP2) is correlated with epithelial ovarian cancer progression

(2009) H Chen et al.   BRITISH JOURNAL OF CANCER

Engagement of CD44 by hyaluronan suppresses TLR4 signaling and the septic response to LPS

(2009) Jun Muto et al.   MOLECULAR IMMUNOLOGY

Involvement of human CD44 during Cryptococcus neoformans infection of brain microvascular endothelial cells

(2008) Ambrose Jong et al.   CELLULAR MICROBIOLOGY