Targeting glypican-4 overcomes 5-FU resistance and attenuates stem cell-like properties via suppression of Wnt/β-catenin pathway in pancreatic cancer cells

Early detection of pancreatic cancer: Where are we now and where are we going?

(2017) Bin Zhou et al.   INTERNATIONAL JOURNAL OF CANCER

Breast cancer stem cells as last soldiers eluding therapeutic burn: A hard nut to crack

(2017) Pritish Nilendu et al.   INTERNATIONAL JOURNAL OF CANCER

The epithelial to mesenchymal transition (EMT) and cancer stem cells: implication for treatment resistance in pancreatic cancer

(2017) Pingting Zhou et al.   Molecular Cancer

GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses

(2017) Zefang Tang et al.   NUCLEIC ACIDS RESEARCH

Molecular alterations contributing to pancreatic cancer chemoresistance

(2017) Azam Rajabpour et al.   PANCREATOLOGY

Up-regulation of lncRNA SNHG1 indicates poor prognosis and promotes cell proliferation and metastasis of colorectal cancer by activation of the Wnt/β-catenin signaling pathway

(2017) Yuping Zhu et al.   Oncotarget

KLF4-Mediated Suppression of CD44 Signaling Negatively Impacts Pancreatic Cancer Stemness and Metastasis

(2016) Yongmin Yan et al.   CANCER RESEARCH

A positive feedback loop involving the Wnt/β-catenin/MYC/Sox2 axis defines a highly tumorigenic cell subpopulation in ALK-positive anaplastic large cell lymphoma

(2016) Chengsheng Wu et al.   Journal of Hematology & Oncology

Pancreatic cancer

(2016) Terumi Kamisawa et al.   LANCET

Cell surface heparan sulfate proteoglycans as novel markers of human neural stem cell fate determination

(2016) Lotta E. Oikari et al.   Stem Cell Research

Glypican-4 gene polymorphism (rs1048369) and susceptibility to Epstein-Barr virus-associated and -negative gastric carcinoma

(2016) Danrui Zhao et al.   VIRUS RESEARCH

Tumour-derived exosomes as a signature of pancreatic cancer - liquid biopsies as indicators of tumour progression

(2016) Zarin Nuzhat et al.   Oncotarget

Cancer Stem Cell-Based Models of Colorectal Cancer Reveal Molecular Determinants of Therapy Resistance

(2016) Maria Laura De Angelis et al.   Stem Cells Translational Medicine

Comparative genetic screens in human cells reveal new regulatory mechanisms in WNT signaling

(2016) Andres M Lebensohn et al.   eLife

Pancreatic cancer stem cells: New insight into a stubborn disease

(2015) Han-xiang Zhan et al.   CANCER LETTERS

Glypican4 promotes cardiac specification and differentiation by attenuating canonical Wnt and Bmp signaling

(2015) I. Strate et al.   DEVELOPMENT

A role of glypican4 and wnt5b in chondrocyte stacking underlying craniofacial cartilage morphogenesis

(2015) Barbara E. Sisson et al.   MECHANISMS OF DEVELOPMENT

Novel Holistic Approaches for Overcoming Therapy Resistance in Pancreatic and Colon Cancers

(2015) Fazlul H. Sarkar   MEDICAL PRINCIPLES AND PRACTICE

Glypican-1 identifies cancer exosomes and detects early pancreatic cancer

(2015) Sonia A. Melo et al.   NATURE

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

miR-33a suppresses the nuclear translocation of β-catenin to enhance gemcitabine sensitivity in human pancreatic cancer cells

(2015) Chen Liang et al.   TUMOR BIOLOGY

Slug-Dependent Upregulation of L1CAM Is Responsible for the Increased Invasion Potential of Pancreatic Cancer Cells following Long-Term 5-FU Treatment

(2015) Kaja Lund et al.   PLoS One

Pancreatic Cancer Stem-like Cells Display Aggressive Behavior Mediated via Activation of FoxQ1

(2014) Bin Bao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of glypicans in Hedgehog signaling

(2014) Jorge Filmus et al.   MATRIX BIOLOGY

Biology and Clinical Applications of Pancreatic Cancer Stem Cells

(2013) Ethan V. Abel et al.   GASTROENTEROLOGY

Heparan Sulfate Proteoglycans and Human Breast Cancer Epithelial Cell Tumorigenicity

(2013) Rachel K. Okolicsanyi et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Epigenetic Regulation of SOX9 by the NF-κB Signaling Pathway in Pancreatic Cancer Stem Cells

(2013) Lei Sun et al.   STEM CELLS

Dynamic regulation of cancer stem cells and clinical challenges

(2012) Chao Ni et al.   Clinical & Translational Oncology

Localization of glypican-4 in different membrane microdomains is involved in the regulation of Wnt signaling

(2012) H. Sakane et al.   JOURNAL OF CELL SCIENCE

Modulating Glypican4 Suppresses Tumorigenicity of Embryonic Stem Cells While Preserving Self-Renewal and Pluripotency

(2012) Annalisa Fico et al.   STEM CELLS

Pancreatic cancer: Overview of descriptive epidemiology

(2011) Cristina Bosetti et al.   MOLECULAR CARCINOGENESIS

Novel duplication in glypican-4 as an apparent cause of Simpson-Golabi-Behmel syndrome

(2010) John Waterson et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Glucosylceramide synthase upregulates MDR1 expression in the regulation of cancer drug resistance through cSrc and β-catenin signaling

(2010) Yong-Yu Liu et al.   Molecular Cancer

Pancreatic Cancer Stem Cells

(2008) Cheong J. Lee et al.   JOURNAL OF CLINICAL ONCOLOGY

Fine-tuning of cell signaling by glypicans

(2007) A. Fico et al.   CELLULAR AND MOLECULAR LIFE SCIENCES