Emerging role of Twist1 in fibrotic diseases

Celastrol protects TGF-β1-induced endothelial-mesenchymal transition

(2017) Fei Gong et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

Loss of Twist1 in the Mesenchymal Compartment Promotes Increased Fibrosis in Experimental Lung Injury by Enhanced Expression of CXCL12

(2017) Jiangning Tan et al.   JOURNAL OF IMMUNOLOGY

Epithelial-to-mesenchymal transition in tumor progression

(2017) Elena Prieto-García et al.   MEDICAL ONCOLOGY

The epithelial to mesenchymal transition (EMT) and cancer stem cells: implication for treatment resistance in pancreatic cancer

(2017) Pingting Zhou et al.   Molecular Cancer

BRD4 mediates NF-κB-dependent epithelial-mesenchymal transition and pulmonary fibrosis via transcriptional elongation

(2016) Bing Tian et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Role of Twist1 Phosphorylation in Angiogenesis and Pulmonary Fibrosis

(2016) Tadanori Mammoto et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Composition of TWIST1 dimers regulates fibroblast activation and tissue fibrosis

(2016) Katrin Palumbo-Zerr et al.   ANNALS OF THE RHEUMATIC DISEASES

AKT1 Inhibits Epithelial-to-Mesenchymal Transition in Breast Cancer through Phosphorylation-Dependent Twist1 Degradation

(2016) Chia-Wei Li et al.   CANCER RESEARCH

Epithelial-mesenchymal transition in tissue repair and fibrosis

(2016) Rivka C. Stone et al.   CELL AND TISSUE RESEARCH

Expanding roles of the hypoxia-response network in chronic kidney disease

(2016) Tetsuhiro Tanaka   Clinical and Experimental Nephrology

Statin pretreatment inhibits the lipopolysaccharide-induced epithelial-mesenchymal transition via the downregulation of toll-like receptor 4 and nuclear factor-κB in human biliary epithelial cells

(2016) Yangmi Kim et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Elevation of Twist expression by arecoline contributes to the pathogenesis of oral submucous fibrosis

(2016) Yu-Hsien Lee et al.   JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION

Partial Epithelial-to-Mesenchymal Transition and Other New Mechanisms of Kidney Fibrosis

(2016) Sara Lovisa et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

MicroRNA-130b improves renal tubulointerstitial fibrosis via repression of Snail-induced epithelial-mesenchymal transition in diabetic nephropathy

(2016) Xiaoyan Bai et al.   Scientific Reports

Overexpression of Inhibitor of DNA-Binding 2 Attenuates Pulmonary Fibrosis through Regulation of c-Abl and Twist

(2015) Jibing Yang et al.   AMERICAN JOURNAL OF PATHOLOGY

Twist Contributes to Proliferation and Epithelial-to-Mesenchymal Transition–Induced Fibrosis by Regulating YB-1 in Human Peritoneal Mesothelial Cells

(2015) Lijie He et al.   AMERICAN JOURNAL OF PATHOLOGY

Suppression of fibrogenic signaling in hepatic stellate cells by Twist1-dependent microRNA-214 expression: Role of exosomes in horizontal transfer of Twist1

(2015) Li Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Epigenetic Activation of TWIST1 by MTDH Promotes Cancer Stem-like Cell Traits in Breast Cancer

(2015) Y. Liang et al.   CANCER RESEARCH

Epithelial-mesenchymal transition: An emerging target in tissue fibrosis

(2015) Meirong Li et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Macrophage-derived vascular endothelial growth factor and angiogenesis within the hepatic scar-new pathways unmasked in the resolution of fibrosis

(2015) Jonathan Fallowfield   HEPATOLOGY

Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established disease

(2015) M Teresa Grande et al.   NATURE MEDICINE

Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis

(2015) Sara Lovisa et al.   NATURE MEDICINE

Imipramine blue halts head and neck cancer invasion through promoting F-box and leucine-rich repeat protein 14-mediated Twist1 degradation

(2015) W-H Yang et al.   ONCOGENE

Twist1 and Snail Link Hedgehog Signaling to Tumor-Initiating Cell-Like Properties and Acquired Chemoresistance Independently of ABC Transporters

(2015) Ying Kong et al.   STEM CELLS

The role of TWIST1 in epithelial-mesenchymal transition and cancers

(2015) Qing-Qing Zhu et al.   TUMOR BIOLOGY

Hypoxia-induced Bmi1 promotes renal tubular epithelial cell–mesenchymal transition and renal fibrosis via PI3K/Akt signal

(2014) Rui Du et al.   MOLECULAR BIOLOGY OF THE CELL

Epithelio-mesenchymal transitional attributes in oral sub-mucous fibrosis

(2013) Raunak Kumar Das et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Molecular basis of organ fibrosis: Potential therapeutic approaches

(2013) Asish K Ghosh et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

TWIST1 promoter methylation is associated with prognosis in tonsillar squamous cell carcinoma

(2013) Mi Jung Kwon et al.   HUMAN PATHOLOGY

All-transretinoic acid ameliorates bleomycin-induced lung fibrosis by downregulating the TGF-β1/Smad3 signaling pathway in rats

(2013) Xiaodong Song et al.   LABORATORY INVESTIGATION

Twist Is a New Prognostic Marker for Renal Survival in Patients with Chronic Kidney Disease

(2012) Shiren Sun et al.   AMERICAN JOURNAL OF NEPHROLOGY

Differential modulation of surfactant protein D under acute and persistent hypoxia in acute lung injury

(2012) Koji Sakamoto et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Sphingosine-1-phosphate as a mediator involved in development of fibrotic diseases

(2012) Yoh Takuwa et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Activation of the Notch1/STAT3/Twist signaling axis promotes gastric cancer progression

(2012) Kai-Wen Hsu et al.   CARCINOGENESIS

Novel evidence demonstrates that epithelial-mesenchymal transition contributes to nephrolithiasis-induced renal fibrosis

(2012) Min Liu et al.   JOURNAL OF SURGICAL RESEARCH

Epigenetic reprogramming and post-transcriptional regulation during the epithelial–mesenchymal transition

(2012) Chung-Yin Wu et al.   TRENDS IN GENETICS

Phosphorylation of Serine 68 of Twist1 by MAPKs Stabilizes Twist1 Protein and Promotes Breast Cancer Cell Invasiveness

(2011) J. Hong et al.   CANCER RESEARCH

The role of EMT in renal fibrosis

(2011) Rosemarie M. Carew et al.   CELL AND TISSUE RESEARCH

Normal and disease-related biological functions of Twist1 and underlying molecular mechanisms

(2011) Qian Qin et al.   CELL RESEARCH

IL-6 Stabilizes Twist and Enhances Tumor Cell Motility in Head and Neck Cancer Cells through Activation of Casein Kinase 2

(2011) Ying-Wen Su et al.   PLoS One

Betel-derived alkaloid up-regulates keratinocyte alphavbeta6 integrin expression and promotes oral submucous fibrosis

(2010) Karwan A Moutasim et al.   JOURNAL OF PATHOLOGY

Bmi1 is essential in Twist1-induced epithelial–mesenchymal transition

(2010) Muh-Hwa Yang et al.   NATURE CELL BIOLOGY

miR-200b Precursor Can Ameliorate Renal Tubulointerstitial Fibrosis

(2010) Shigeyoshi Oba et al.   PLoS One

Chronic cadmium exposure induces transcriptional activation of the Wnt pathway and upregulation of epithelial-to-mesenchymal transition markers in mouse kidney

(2010) Prabir K. Chakraborty et al.   TOXICOLOGY LETTERS

Gene Expression Profiling of Pulmonary Fibrosis Identifies Twist1 as an Antiapoptotic Molecular “Rectifier” of Growth Factor Signaling

(2009) Robert S. Bridges et al.   AMERICAN JOURNAL OF PATHOLOGY

Characterization of sequences in human TWIST required for nuclear localization

(2009) Shalini Singh et al.   BMC CELL BIOLOGY

Complete reversal of epithelial to mesenchymal transition requires inhibition of both ZEB expression and the Rho pathway

(2009) Shreyas Das et al.   BMC CELL BIOLOGY

A twist of insight - the role of Twist-family bHLH factors in development

(2009) Ralston M. Barnes et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

RGC-32 Mediates Transforming Growth Factor-β-induced Epithelial-Mesenchymal Transition in Human Renal Proximal Tubular Cells

(2009) Wen-Yan Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

Wnt/ -Catenin Signaling Promotes Renal Interstitial Fibrosis

(2009) W. He et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Hypoxia-inducible factor-1α induces Twist expression in tubular epithelial cells subjected to hypoxia, leading to epithelial-to-mesenchymal transition

(2009) Shiren Sun et al.   KIDNEY INTERNATIONAL

Twist: a new link from hypoxia to fibrosis

(2009) Wibke Bechtel et al.   KIDNEY INTERNATIONAL

Twist: A Regulator of Epithelial-Mesenchymal Transition in Lung Fibrosis

(2009) Veronika Pozharskaya et al.   PLoS One

Methylation of the TWIST1 Promoter, TWIST1 mRNA Levels, and Immunohistochemical Expression of TWIST1 in Breast Cancer

(2008) E. H. Gort et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Twist1 homodimers enhance FGF responsiveness of the cranial sutures and promote suture closure

(2008) Jeannette Connerney et al.   DEVELOPMENTAL BIOLOGY