Primary cilia sensitize endothelial cells to BMP and prevent excessive vascular regression

Endoglin prevents vascular malformation by regulating flow-induced cell migration and specification through VEGFR2 signalling

(2017) Yi Jin et al.   NATURE CELL BIOLOGY

IFT proteins spatially control the geometry of cleavage furrow ingression and lumen positioning

(2017) Nicolas Taulet et al.   Nature Communications

Endothelial Mechanosignaling: Does One Sensor Fit All?

(2016) Chris Givens et al.   ANTIOXIDANTS & REDOX SIGNALING

Alk1 controls arterial endothelial cell migration in lumenized vessels

(2016) Elizabeth R. Rochon et al.   DEVELOPMENT

Endothelial primary cilia inhibit atherosclerosis

(2016) Colin Dinsmore et al.   EMBO REPORTS

Defective fluid shear stress mechanotransduction mediates hereditary hemorrhagic telangiectasia

(2016) Nicolas Baeyens et al.   JOURNAL OF CELL BIOLOGY

Endothelial fluid shear stress sensing in vascular health and disease

(2016) Nicolas Baeyens et al.   JOURNAL OF CLINICAL INVESTIGATION

Endocytic Control of Cellular Signaling at the Primary Cilium

(2016) Lotte B. Pedersen et al.   TRENDS IN BIOCHEMICAL SCIENCES

Non-canonical Wnt signalling modulates the endothelial shear stress flow sensor in vascular remodelling

(2016) Claudio A Franco et al.   eLife

TGFβ1 – induced recruitment of human bone mesenchymal stem cells is mediated by the primary cilium in a SMAD3-dependent manner

(2016) Marie-Noëlle Labour et al.   Scientific Reports

Dynamic Endothelial Cell Rearrangements Drive Developmental Vessel Regression

(2015) Claudio A. Franco et al.   PLOS BIOLOGY

Vascular remodeling is governed by a VEGFR3-dependent fluid shear stress set point

(2015) Nicolas Baeyens et al.   eLife

A Cilia Independent Role of Ift88/Polaris during Cell Migration

(2015) Christopher Boehlke et al.   PLoS One

Microvascular Endothelial Cells Migrate Upstream and Align Against the Shear Stress Field Created by Impinging Flow

(2014) Maggie A. Ostrowski et al.   BIOPHYSICAL JOURNAL

Endothelial Cilia Are Essential for Developmental Vascular Integrity in Zebrafish

(2014) S. Kallakuri et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Computer simulations reveal complex distribution of haemodynamic forces in a mouse retina model of angiogenesis

(2014) M. O. Bernabeu et al.   Journal of the Royal Society Interface

Endothelial Cilia Mediate Low Flow Sensing during Zebrafish Vascular Development

(2014) Jacky G. Goetz et al.   Cell Reports

Endothelial Cell Sensing of Flow Direction

(2013) Chong Wang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

SRF selectively controls tip cell invasive behavior in angiogenesis

(2013) C. A. Franco et al.   DEVELOPMENT

Circulating Bmp10 acts through endothelial Alk1 to mediate flow-dependent arterial quiescence

(2013) D. W. Laux et al.   DEVELOPMENT

Filopodia are dispensable for endothelial tip cell guidance

(2013) Li-Kun Phng et al.   DEVELOPMENT

Dynamic responses of endothelial cells to changes in blood flow during vascular remodeling of the mouse yolk sac

(2013) Ryan S. Udan et al.   DEVELOPMENT

Kif3a Guides Microtubular Dynamics, Migration and Lumen Formation of MDCK Cells

(2013) Christopher Boehlke et al.   PLoS One

Vascular remodeling after ischemic stroke: Mechanisms and therapeutic potentials

(2013) Jialing Liu et al.   PROGRESS IN NEUROBIOLOGY

IFT88 Plays a Cilia- and PCP-Independent Role in Controlling Oriented Cell Divisions during Vertebrate Embryonic Development

(2013) Antonia Borovina et al.   Cell Reports

High Wall Shear Stress and Spatial Gradients in Vascular Pathology: A Review

(2012) Jennifer M. Dolan et al.   ANNALS OF BIOMEDICAL ENGINEERING

Kinesin motors and primary cilia

(2012) Kristen J. Verhey et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

ALK1 Signaling Inhibits Angiogenesis by Cooperating with the Notch Pathway

(2012) Bruno Larrivée et al.   DEVELOPMENTAL CELL

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Force-specific activation of Smad1/5 regulates vascular endothelial cell cycle progression in response to disturbed flow

(2012) J. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TGF-  Signaling in Endothelial-to-Mesenchymal Transition: The Role of Shear Stress and Primary Cilia

(2012) P. ten Dijke et al.   Science Signaling

Haemodynamics-Driven Developmental Pruning of Brain Vasculature in Zebrafish

(2012) Qi Chen et al.   PLOS BIOLOGY

Basic and Therapeutic Aspects of Angiogenesis

(2011) Michael Potente et al.   CELL

Lack of Primary Cilia Primes Shear-Induced Endothelial-to-Mesenchymal Transition

(2011) Anastasia D. Egorova et al.   CIRCULATION RESEARCH

The cilia protein IFT88 is required for spindle orientation in mitosis

(2011) Benedicte Delaval et al.   NATURE CELL BIOLOGY

Mechanism and Regulation of Nucleocytoplasmic Trafficking of Smad

(2011) Xiaochu Chen et al.   Cell and Bioscience

The primary cilium at a glance

(2010) P. Satir et al.   JOURNAL OF CELL SCIENCE

The Effects of Hemodynamic Force on Embryonic Development

(2010) JAMES C. CULVER et al.   MICROCIRCULATION

Vangl2 directs the posterior tilting and asymmetric localization of motile primary cilia

(2010) Antonia Borovina et al.   NATURE CELL BIOLOGY

The primary cilium: a signalling centre during vertebrate development

(2010) Sarah C. Goetz et al.   NATURE REVIEWS GENETICS

Domain architecture of the atypical Arf-family GTPase Arl13b involved in cilia formation

(2008) Yuji Hori et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Signaling cross-talk between TGF-β/BMP and other pathways

(2008) Xing Guo et al.   CELL RESEARCH

Endothelial Cilia Are Fluid Shear Sensors That Regulate Calcium Signaling and Nitric Oxide Production Through Polycystin-1

(2008) Surya M. Nauli et al.   CIRCULATION

Efficient, inducible Cre-recombinase activation in vascular endothelium

(2008) Suzanne Claxton et al.   GENESIS