Unraveling the molecular mechanism of interactions of the Rho GTPases Cdc42 and Rac1 with the scaffolding protein IQGAP2

Global treadmilling coordinates actin turnover and controls the size of actin networks

(2017) Marie-France Carlier et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Membrane-associated Ras dimers are isoform-specific: K-Ras dimers differ from H-Ras dimers

(2016) H. Jang et al.   BIOCHEMICAL JOURNAL

IQGAP1 Interaction with RHO Family Proteins Revisited

(2016) Kazem Nouri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rho GTPases: Anti- or pro-neoplastic targets?

(2016) I Zandvakili et al.   ONCOGENE

The Structural Basis for Cdc42-Induced Dimerization of IQGAPs

(2016) Louis LeCour et al.   STRUCTURE

IQGAPs as Key Regulators of Actin-cytoskeleton Dynamics

(2015) Takashi Watanabe et al.   CELL STRUCTURE AND FUNCTION

IQGAPs choreograph cellular signaling from the membrane to the nucleus

(2015) Jessica M. Smith et al.   TRENDS IN CELL BIOLOGY

IQGAP1 Binds to Estrogen Receptor-α and Modulates Its Function

(2014) Huseyin H. Erdemir et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Weighted Implementation of Suboptimal Paths (WISP): An Optimized Algorithm and Tool for Dynamical Network Analysis

(2014) Adam T. Van Wart et al.   Journal of Chemical Theory and Computation

PRISM: a web server and repository for prediction of protein–protein interactions and modeling their 3D complexes

(2014) Alper Baspinar et al.   NUCLEIC ACIDS RESEARCH

Assessing the performance of MM/PBSA and MM/GBSA methods. 4. Accuracies of MM/PBSA and MM/GBSA methodologies evaluated by various simulation protocols using PDBbind data set

(2014) Huiyong Sun et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Dynamic multiprotein assemblies shape the spatial structure of cell signaling

(2014) Ruth Nussinov et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

A broad view of scaffolding suggests that scaffolding proteins can actively control regulation and signaling of multienzyme complexes through allostery

(2013) Ruth Nussinov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

The Ras GTPase-activating-like Protein IQGAP1 Mediates Nrf2 Protein Activation via the Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase (ERK) Kinase (MEK)-ERK Pathway

(2013) Ka Lung Cheung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IQGAP1 scaffold-kinase interaction blockade selectively targets RAS-MAP kinase–driven tumors

(2013) Katherine L Jameson et al.   NATURE MEDICINE

Rho Isoform-specific Interaction with IQGAP1 Promotes Breast Cancer Cell Proliferation and Migration

(2012) Darren E. Casteel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Ras protein superfamily: Evolutionary tree and role of conserved amino acids

(2012) Ana Maria Rojas et al.   JOURNAL OF CELL BIOLOGY

Role of Rho GTPases and their regulators in cancer progression

(2011) Rajamani Rathinam   Frontiers in Bioscience-Landmark

HotRegion: a database of predicted hot spot clusters

(2011) E. Cukuroglu et al.   NUCLEIC ACIDS RESEARCH

CHARMM: The biomolecular simulation program

(2009) B. R. Brooks et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

ras oncogenes: their role in neoplasia

(2008) M. BARBACID   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Mammalian Rho GTPases: new insights into their functions from in vivo studies

(2008) Sarah J. Heasman et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY