Phosphorylation-mediated structural changes within the SOAR domain of stromal interaction molecule 1 enable specific activation of distinct Orai channels

Molecular anatomy of the early events in STIM1 activation – oligomerization or conformational change?

(2017) Marek K. Korzeniowski et al.   JOURNAL OF CELL SCIENCE

Molecular mechanisms of STIM/Orai communication

(2016) Isabella Derler et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Anchoring protein AKAP79-mediated PKA phosphorylation of STIM1 determines selective activation of the ARC channel, a store-independent Orai channel

(2015) Jill L. Thompson et al.   JOURNAL OF PHYSIOLOGY-LONDON

STIM1 dimers undergo unimolecular coupling to activate Orai1 channels

(2015) Yandong Zhou et al.   Nature Communications

Lightweight object oriented structure analysis: Tools for building tools to analyze molecular dynamics simulations

(2014) Tod D. Romo et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Effects of pseudophosphorylation mutants on the structural dynamics of smooth muscle myosin regulatory light chain

(2014) L. Michel Espinoza-Fonseca et al.   Molecular BioSystems

Distinct Orai-coupling domains in STIM1 and STIM2 define the Orai-activating site

(2014) Xizhuo Wang et al.   Nature Communications

CHARMM36 all-atom additive protein force field: Validation based on comparison to NMR data

(2013) Jing Huang et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Molecular basis of activation of the arachidonate-regulated Ca2+(ARC) channel, a store-independent Orai channel, by plasma membrane STIM1

(2013) Jill L. Thompson et al.   JOURNAL OF PHYSIOLOGY-LONDON

Initial activation of STIM1, the regulator of store-operated calcium entry

(2013) Yubin Zhou et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Maximum Allowed Solvent Accessibilites of Residues in Proteins

(2013) Matthew Z. Tien et al.   PLoS One

STIM1/Orai1 coiled-coil interplay in the regulation of store-operated calcium entry

(2013) Peter B. Stathopulos et al.   Nature Communications

A plasma membrane-targeted cytosolic domain of STIM1 selectively activates ARC channels, an arachidonate-regulated store-independent Orai channel

(2012) Jill L. Thompson et al.   Channels

Optimization of the Additive CHARMM All-Atom Protein Force Field Targeting Improved Sampling of the Backbone ϕ, ψ and Side-Chain χ1 and χ2 Dihedral Angles

(2012) Robert B. Best et al.   Journal of Chemical Theory and Computation

Structural and mechanistic insights into the activation of Stromal interaction molecule 1 (STIM1)

(2012) X. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

STIM1 couples to ORAI1 via an intramolecular transition into an extended conformation

(2011) Martin Muik et al.   EMBO JOURNAL

Orai channel-dependent activation of phospholipase C-δ: a novel mechanism for the effects of calcium entry on calcium oscillations

(2011) Jill L. Thompson et al.   JOURNAL OF PHYSIOLOGY-LONDON

A Basic Sequence in STIM1 Promotes Ca2+Influx by Interacting with the C-Terminal Acidic Coiled Coil of Orai1

(2010) Nathaniel Calloway et al.   BIOCHEMISTRY

Essential Role for the CRAC Activation Domain in Store-dependent Oligomerization of STIM1

(2010) Elizabeth D. Covington et al.   MOLECULAR BIOLOGY OF THE CELL

Pore architecture of the ORAI1 store-operated calcium channel

(2010) Y. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of STIM1-Orai1 Involves an Intramolecular Switching Mechanism

(2010) M. K. Korzeniowski et al.   Science Signaling

A minimal regulatory domain in the C terminus of STIM1 binds to and activates ORAI1 CRAC channels

(2009) Takumi Kawasaki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

STIM1 Clusters and Activates CRAC Channels via Direct Binding of a Cytosolic Domain to Orai1

(2009) Chan Young Park et al.   CELL

Arachidonic acid stimulates extracellular Ca2+ entry in rat pancreatic β cells via activation of the noncapacitative arachidonate-regulated Ca2+ (ARC) channels

(2009) Valerie Yeung-Yam-Wah et al.   CELL CALCIUM

A Cytosolic Homomerization and a Modulatory Domain within STIM1 C Terminus Determine Coupling to ORAI1 Channels

(2009) Martin Muik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Determinants of the Coupling between STIM1 and Orai Channels

(2009) Irene Frischauf et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SOAR and the polybasic STIM1 domains gate and regulate Orai channels

(2009) Joseph P. Yuan et al.   NATURE CELL BIOLOGY

Formyl-peptide receptor like 1: A potent mediator of the Ca2+ release-activated Ca2+ current ICRAC

(2008) Yong-Sheng Li et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS