Anchoring protein AKAP79-mediated PKA phosphorylation of STIM1 determines selective activation of the ARC channel, a store-independent Orai channel

Dynamic Assembly of a Membrane Signaling Complex Enables Selective Activation of NFAT by Orai1

(2014) Pulak Kar et al.   CURRENT BIOLOGY

Characterization of selective Calcium-Release Activated Calcium channel blockers in mast cells and T-cells from human, rat, mouse and guinea-pig preparations

(2013) Louise V. Rice et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

17β-Estradiol Inhibits Phosphorylation of Stromal Interaction Molecule 1 (STIM1) Protein

(2013) John T. Sheridan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular basis of activation of the arachidonate-regulated Ca2+(ARC) channel, a store-independent Orai channel, by plasma membrane STIM1

(2013) Jill L. Thompson et al.   JOURNAL OF PHYSIOLOGY-LONDON

Characterization of a novel CRAC inhibitor that potently blocks human T cell activation and effector functions

(2013) Gang Chen et al.   MOLECULAR IMMUNOLOGY

Antibody-Mediated Targeting of the Orai1 Calcium Channel Inhibits T Cell Function

(2013) Jennifer H. Cox et al.   PLoS One

STIM1/Orai1 coiled-coil interplay in the regulation of store-operated calcium entry

(2013) Peter B. Stathopulos et al.   Nature Communications

STIM1 tyrosine-phosphorylation is required for STIM1-Orai1 association in human platelets

(2012) Esther Lopez et al.   CELLULAR SIGNALLING

A plasma membrane-targeted cytosolic domain of STIM1 selectively activates ARC channels, an arachidonate-regulated store-independent Orai channel

(2012) Jill L. Thompson et al.   Channels

Structural and mechanistic insights into the activation of Stromal interaction molecule 1 (STIM1)

(2012) X. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Orai channel-dependent activation of phospholipase C-δ: a novel mechanism for the effects of calcium entry on calcium oscillations

(2011) Jill L. Thompson et al.   JOURNAL OF PHYSIOLOGY-LONDON

A Basic Sequence in STIM1 Promotes Ca2+Influx by Interacting with the C-Terminal Acidic Coiled Coil of Orai1

(2010) Nathaniel Calloway et al.   BIOCHEMISTRY

Phosphorylation of STIM1 at ERK1/2 target sites modulates store-operated calcium entry

(2010) E. Pozo-Guisado et al.   JOURNAL OF CELL SCIENCE

Activation of STIM1-Orai1 Involves an Intramolecular Switching Mechanism

(2010) M. K. Korzeniowski et al.   Science Signaling

STIM1 Clusters and Activates CRAC Channels via Direct Binding of a Cytosolic Domain to Orai1

(2009) Chan Young Park et al.   CELL

Molecular Determinants of the Coupling between STIM1 and Orai Channels

(2009) Irene Frischauf et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting Gut T Cell Ca2+ Release-Activated Ca2+ Channels Inhibits T Cell Cytokine Production and T-Box Transcription Factor T-Bet in Inflammatory Bowel Disease

(2009) A. Di Sabatino et al.   JOURNAL OF IMMUNOLOGY

Phosphorylation of STIM1 underlies suppression of store-operated calcium entry during mitosis

(2009) Jeremy T. Smyth et al.   NATURE CELL BIOLOGY

Orai1 internalization and STIM1 clustering inhibition modulate SOCE inactivation during meiosis

(2009) F. Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CRAC inhibitors: identification and potential

(2008) Isabella Derler et al.   Expert Opinion on Drug Discovery

Oligomerization of STIM1 couples ER calcium depletion to CRAC channel activation

(2008) Riina M. Luik et al.   NATURE

Both Orai1 and Orai3 are essential components of the arachidonate-regulated Ca2+-selective (ARC) channels

(2007) Olivier Mignen et al.   JOURNAL OF PHYSIOLOGY-LONDON